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Kai Kupferschmidt Profile picture
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13 Apr, 4 tweets, 3 min read
Gerade etwas verdutzt festgestellt, dass wir @pandemiapodcast jetzt schon seit mehr als einem Jahr machen. Am 13.4.2020 kam unsere zweite Folge raus, in der wir über Ebola in Liberia sprechen.
Was war eure Lieblingsfolge? Was würdet ihr gern noch hören?

viertausendhertz.de/pan02/
Und unsere aktuelle Folge zur Situation auf den Intensivstationen liegt @nsemak, @SalmLaura und mir besondes am Herzen.
Falls ihr sie noch nicht gehört habt, hier entlang:
viertausendhertz.de/pan22/
Und an dieser Stelle etwas verspätet ein riesiges Dankeschön an alle, die uns im ersten Jahr unterstützt haben!
@pandemiapodcast ist ein Herzensprojekt, aber die Finanzierung ist nach wie vor schwierig und wir hätten es nicht bis hierhin geschafft ohne großartige Unterstützung:
Darum Dank an @riffreporter und @wpk_daily!
Dank an all die Forscher, Ärzte, Betroffene und Bewegte, die mit uns gesprochen haben.
Und vor allem Danke an die Hörer für all das wichtige Feedback, die netten Bewertungen und die Unterstützung im Klub Pandemia
steadyhq.com/de/pandemia/ab…

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More from @kakape

Kai Kupferschmidt Profile picture
14 Apr
Most fascinating bit of ACIP meeting so far is a detail on the 25-year old male in J&J trial, who developed CVST with hemorrhage after 8 days.
J&J representative says it was retrospectively determined that he was negative for anti-PF4 antibodies before vaccination, positive after
Case reports are fascinating.
Here are some details on the case from previous tweet.
(Short sentence on anti-PF4 antibodies is a bit misleading here: he was negative at baseline, positive post-vaccination according to the presentation) Image
Helpful timeline here: Image
Read 32 tweets
Kai Kupferschmidt Profile picture
14 Apr
Denmark just announced they will not restart vaccinations with AstraZeneca’s #covid19 shots and instead rely on the other vaccines.

“Danish-Norwegian registry studies have revealed a higher than expected frequency in the number of specific side effects”

sst.dk/en/english/new…
As I have said before these decisions depend a lot on context. In this case:
- infections are low
- other vaccines available and
- oldest people largely vaccinated (so future vaccinees would be younger)

Different places will come to different conclusions and that’s reasonable.
"In the midst of an epidemic, it has been a difficult decision to continue our vaccination programme without an effective and readily available vaccine against COVID-19. However, we have other vaccines at our disposal, and the epidemic is currently under control.”
Read 4 tweets
Kai Kupferschmidt Profile picture
13 Apr
“While these events are very rare, we’re recommending a pause in the use of the J&J #COVID19 vaccine in order to prepare the healthcare system to recognize and treat patients appropriately and to report severe events they may be seeing in people”, says @CDCgov’s Anne Schuchat.
@CDCgov Q how long the pause may be
“The timeframe will depend obviously on what we learn in the next few days. However, we expect it to be a matter of days for this pause”, says @DrWoodcockFDA.
@CDCgov @DrWoodcockFDA "The issue here with these types of blood clots, is that if one administers the standard treatments that we as doctors have learned to give for blood clots, one can actually cause tremendous harm or the outcome can be fatal”, says Peter Marks.
Read 9 tweets
Kai Kupferschmidt Profile picture
13 Apr
I just don’t get it, @NateSilver538. I admire your work on polling and you clearly appreciate the complexity there.
You can argue about the FDA decision for sure, but pretending it is blindingly obvious that they are wrong, simply isn’t true or fair to this situation.
As so often in this pandemic, I agree with @angie_rasmussen here.
I don’t think vaccinated individuals need to lose sleep over this, but I certainly want people at the agency tasked with ensuring the safety of vaccines to lose a little sleep over this.
Another good voice of reason when it comes to vaccines is @nataliexdean
Read 4 tweets
Kai Kupferschmidt Profile picture
13 Apr
US FDA is recommending a pause in the use of the J&J #covid19 vaccine while they investigate 6 reported cases of the kind of rare clotting disorder seen after AZ vaccine too.
Should not come as a huge surprise to those of you who have been following the reporting on this.
As @GretchenVogel1 and I wrote last week, EMA is already investigating this safety signal.
Given that this vaccine (like AZ one) too uses an adenovirus to deliver the genetic instructions for #SARSCoV2 spike protein, there were worries about this.

sciencemag.org/news/2021/04/h…
@GretchenVogel1 There will be a press conference at 10am ET that may have more information.
But for now, think of this as a cautious approach to a safety signal, similar to what, for instance, PEI in Germany did when reports of AZ side effects emerged almost exactly a month ago.
Read 4 tweets
Kai Kupferschmidt Profile picture
12 Apr
“We have now seen seven consecutive weeks of increasing cases and four weeks of increasing deaths”, says @DrTedros at @WHO presser on #covid19. “Last week was the fourth highest number of cases in a single week so far."
@DrTedros @WHO "This is despite the fact that more than 780 million doses of vaccine have now been administered globally”, says @DrTedros.
"Make no mistake, vaccines are a vital and powerful tool, but they are not the only tool."
@DrTedros @WHO “Confusion, complacency and inconsistency in public health measures, and their application are driving transmission and costing lives”, says @DrTedros.
"It takes a consistent, coordinated and comprehensive approach."
Read 15 tweets

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