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Eric Feigl-Ding Profile picture
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15 Apr, 4 tweets, 2 min read
💡GOOD NEWS—Moderna expects to have a #COVID19 vaccine booster shot available by the fall adapted for likely the #B1351 🇿🇦 variant. For the past month, NIH has been testing 3rd vaccine doses to enhance Moderna’s efficacy against emerging variants. 🧵 cnbc.com/2021/04/14/cov…
2) Experts hope the new booster shots will help protect against B.1.351, which has been shown to reduce the efficacy of vaccines. Moderna anticipates that annual COVID booster shots will become commonplace, and develop a combination flu and COVID vaccine in the future.
3) The Massachusetts-based biotech firm expects to submit booster shot data to U.S. regulators within a few months, Bancel told CNBC on Wednesday
4) “Bancel's comments came one day after Moderna announced its existing vaccine was more than 90% effective at protecting against Covid up to 6 months after the second dose. It was more than 95% effective against severe disease within that same time frame. cnbc.com/2021/04/13/cov…

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Eric Feigl-Ding Profile picture
17 Apr
SEQUENCING CLUES—#COVID19 spread on an international flight, in a hotel corridor and then to household contacts despite efforts to isolate & quarantine patients, New Zealand reports. Careful genomic tracing confirmed the spread among 9 patients.
cnn.com/travel/article…
2) “One of those infected had spent 14 days in quarantine after being evacuated on a chartered 747 jet from India to New Zealand last August and had tested negative twice.
Others were infected on flight, even though 1/3 full and passengers were spaced apart from one another.”
3) in Singapore, some travelers tested negative during quarantine and then through routine tests they were found to be positive—serological (antibody) test results were positive too. moh.gov.sg/news-highlight…
Read 6 tweets
Eric Feigl-Ding Profile picture
17 Apr
Wow—$1.7 billion investment in fighting #COVID19 variants just announced by Biden Administration to help states and other jurisdictions more effectively fight these mutations—including $1 billion for ramping up gene sequencing! That’s 🇺🇸 leadership. 🧵
whitehouse.gov/briefing-room/… Image
2) “An essential component of the response to the emerging COVID-19 variants is increasing the country’s genomic sequencing — process by which COVID DNA is decoded and potentially deadly mutations in the virus are detected.”

Hear that BC 🇨🇦 health Chief @DrBonnieHenry? #bcpoli Image
3) Many places not sequencing enough. But some places like BC 🇨🇦 is refusing outright to sequence new cases regularly. Instead they will only do sparse background sequencing. Here was BC’s final sequencing report before regular sequencing stopped.
Read 9 tweets
Eric Feigl-Ding Profile picture
17 Apr
CONFIRMED—the very infectious #P1 variant is cause of @Canucks outbreak, team’s general manager confirmed. He also said P1 variant is why its hockey players were hit harder than other NHL—the virus “buckled” & sickened many of the players #COVID19. 🧵 cbc.ca/news/canada/br… Image
2) “What was different with our situation is with the regular COVID it seemed that after 10 days players were ready to get back on the ice and start working out and performing," he said. "But we had players that when they did that, they still had symptoms."
3) Benning said the virus "buckled" some of the players, and that three or four regulars likely won't be ready when games resume.

Head coach Travis Green, who also contracted COVID-19, has yet to return to practices.
Read 9 tweets
Eric Feigl-Ding Profile picture
17 Apr
HOTEL ROOM CROSS-INFECTION: Australia 🇦🇺 hotel outbreak suggests #COVID19 jumped between hotel rooms—7 returned travellers cases arriving from different countries at different times have same genetic sequence—likely jumped between neighboring hotel rooms.
theguardian.com/world/2021/apr… Image
2) “The seven cases came from two family groups who arrived from different countries on different days. They stayed in adjacent rooms on the 12th floor of the Adina Apartments Hotel at Sydney’s Town Hall.
3) “Staff who worked on the floor when the original case was believed to have been infectious – between 8 and 11 April – are self-isolating.”

It’s possible it was either transmitted via hotel staff or via the air.
Read 10 tweets
Eric Feigl-Ding Profile picture
17 Apr
LEAKY BORDER—Despite pandemic “closing” the US/Canada border, 30,000 truck drivers continue to travel between 🇺🇸 & 🇨🇦 daily—and with **no mandatory #COVID19 testing** and **no quarantine requirements**. Let that sink in—30,000 truckers per day! Not safe.🧵 vpr.org/post/most-us-c… Image
2) On an average day, about 30,000 trucks roll across the U.S.-Canada border, carrying more than $1 billion in trade.

Truckers are exempt from any COVID testing rules. And the industry’s trucking association opposes any mandatory COVID test restrictions.🔥google.com/amp/s/cdllife.…
3) If we know air travelers brings #COVID19 cases between countries, why don’t truck drivers?!?! It makes no sense.

I get they are essential, but cmon, allowing 30,000 truckers to cross 🇺🇸 & 🇨🇦 border unfettered by no mandatory testing or quarantine is BEGGING FOR OUTBREAKS!
Read 7 tweets
Eric Feigl-Ding Profile picture
16 Apr
Oh boy. “some scientists are increasingly concerned that, because of a quirk of our own biology, future iterations of vaccines might not always be quite as effective as they are today”—due to **imprinting**. And maybe worse if you had natural infection. 🧵
statnews.com/2021/04/16/nex…
2) “The concerns stem from a phenomenon that is known as imprinting, sometimes called original antigenic sin, which is believed to affect how we respond to some pathogens.”
3) “In short, when your body is introduced to a particular threat for the first time — either through infection or a vaccine — that encounter sets your immune system’s definition of that virus and what immune weapons it needs to detect and protect against it in the future.”
Read 12 tweets

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