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Eric Feigl-Ding Profile picture
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17 Apr, 11 tweets, 4 min read
HOTEL ROOM CROSS-INFECTION: Australia 🇦🇺 hotel outbreak suggests #COVID19 jumped between hotel rooms—7 returned travellers cases arriving from different countries at different times have same genetic sequence—likely jumped between neighboring hotel rooms.
theguardian.com/world/2021/apr…
2) “The seven cases came from two family groups who arrived from different countries on different days. They stayed in adjacent rooms on the 12th floor of the Adina Apartments Hotel at Sydney’s Town Hall.
3) “Staff who worked on the floor when the original case was believed to have been infectious – between 8 and 11 April – are self-isolating.”

It’s possible it was either transmitted via hotel staff or via the air.
4) Recall, this outbreak was quite a shock to Australia in January. Because none shared the same hotel room. It’s thought to have been airborne - via either the cleaning staff, or the air currents in hallways, or via the air ventilation ducts.
5) this also shows the CRITICAL nature of genetic sequencing of the #SARSCoV2 infections. If it wasn’t for the genetic analysis, we would never know they were all the same source infection.

This is why B.C. 🇨🇦 needs to restart sequencing active cases damnit!
6) Furthermore, it doesn’t matter if air, sea, or land travelers.... we need likely good testing and safe quarantine so they don’t infect others when crossing borders. US and Canada is not truly closed - and 30k truckers crossing a day unsafely.
7) Good time to remind folks that #COVIDisAirborne.

VENTILATION is key. Both ventilation and masks needed to reduce risk indoors. But most buildings not ventilated well enough.

8) “Until we recognise that #COVID19 is airborne we are setting ourselves up for repeated failure”

9) as result of outbreak, quarantine hotels in Victoria, 🇦🇺 have reconfigured ventilation systems so that rooms have a negative pressure compared to corridors.

➡️ This means air does not move into the corridor and potentially infect hotel workers/guests. amp.theage.com.au/national/victo…
10) this is why we need sequencing on massive scale to track cases and variants.
11) damnit why do we repeat these hotel transmission cases?! If it weren’t for genome sequencing, we would never know.

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More from @DrEricDing

Eric Feigl-Ding Profile picture
18 Apr
VACCINE IRONY: "It's almost paradoxical, that on the one hand, they want to be relieved of the restrictions, but on the other hand, they don't want to be vaccinated."

"It just almost doesn't make any sense."

Vaccinate = *more freedom* to live safely.
2) The irony is incredibly insane. Trump-dominated voter districts are much less likely to be vaccinated.
3) And it’s indeed due to greater hesitancy. It’s even a strong correlation with Trump voting fraction.
Read 4 tweets
Eric Feigl-Ding Profile picture
18 Apr
Co-infection is bad news—Scientists in Brazil have identified two cases where people were simultaneously infected with two different variants of #COVID19. Co-infection raises the likelihood of *recombination* admixture that generates more variants. 🧵
cnn.com/2021/03/11/ame… Image
2) According to the study, co-infection raises the possibility of recombination of the genomes of the different strains, which can generate new variants of the coronavirus.
3) "Although there are a few reported cases of reinfection, the possibility of co-infection by E484K adds a new factor to the complex interaction between immune response systems and SARS-CoV-2 Spike mutations," wrote the authors.
Read 5 tweets
Eric Feigl-Ding Profile picture
18 Apr
So tragic—tweeting for his life. This could be anyone. I worry for all the places out there without enough vaccines and a robust healthcare system—which even then can be overwhelmed. This is no joke, and the world is now in it’s worse surge. Stay safe. #COVID19
2) Whatever is happening is India is just so damn tragic. India’s new #B1617 variant is also growing worrisome.
3) Pray for India 🇮🇳
Read 4 tweets
Eric Feigl-Ding Profile picture
17 Apr
SEQUENCING CLUES—#COVID19 spread on an international flight, in a hotel corridor and then to household contacts despite efforts to isolate & quarantine patients, New Zealand reports. Careful genomic tracing confirmed the spread among 9 patients.
cnn.com/travel/article…
2) “One of those infected had spent 14 days in quarantine after being evacuated on a chartered 747 jet from India to New Zealand last August and had tested negative twice.
Others were infected on flight, even though 1/3 full and passengers were spaced apart from one another.”
3) in Singapore, some travelers tested negative during quarantine and then through routine tests they were found to be positive—serological (antibody) test results were positive too. moh.gov.sg/news-highlight…
Read 6 tweets
Eric Feigl-Ding Profile picture
17 Apr
Wow—$1.7 billion investment in fighting #COVID19 variants just announced by Biden Administration to help states and other jurisdictions more effectively fight these mutations—including $1 billion for ramping up gene sequencing! That’s 🇺🇸 leadership. 🧵
whitehouse.gov/briefing-room/…
2) “An essential component of the response to the emerging COVID-19 variants is increasing the country’s genomic sequencing — process by which COVID DNA is decoded and potentially deadly mutations in the virus are detected.”

Hear that BC 🇨🇦 health Chief @DrBonnieHenry? #bcpoli
3) Many places not sequencing enough. But some places like BC 🇨🇦 is refusing outright to sequence new cases regularly. Instead they will only do sparse background sequencing. Here was BC’s final sequencing report before regular sequencing stopped.
Read 9 tweets
Eric Feigl-Ding Profile picture
17 Apr
CONFIRMED—the very infectious #P1 variant is cause of @Canucks outbreak, team’s general manager confirmed. He also said P1 variant is why its hockey players were hit harder than other NHL—the virus “buckled” & sickened many of the players #COVID19. 🧵 cbc.ca/news/canada/br…
2) “What was different with our situation is with the regular COVID it seemed that after 10 days players were ready to get back on the ice and start working out and performing," he said. "But we had players that when they did that, they still had symptoms."
3) Benning said the virus "buckled" some of the players, and that three or four regulars likely won't be ready when games resume.

Head coach Travis Green, who also contracted COVID-19, has yet to return to practices.
Read 13 tweets

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