Higher blood clot risk due to COVID—People who have recovered from #COVID19, regardless of the severity of their disease, may be at risk of developing blood clots due to an overactive immune system. Thread 🧵
straitstimes.com/singapore/heal…
2) “Blood samples from 30 patients who had recovered from mild, moderate and severe Covid-19 were collected a month after they had been discharged from the hospital.
3) “All of them were found to have blood vessel damage, possibly arising from a lingering immune response, which could trigger the formation of blood clots.
Around half of the patients had pre-existing cardiovascular risks, such as diabetes and hypertension.
4) “Speaking at a virtual media briefing, she noted that these patients also had more pronounced blood vessel dysfunction compared with the group who had no cardiovascular risks.
5) “the Sars-CoV-2 virus may attack the linings of blood vessels, causing inflammation and damage. This could result in leakage from these damaged vessels, triggering the formation of blood clots, she added.
6) “However, the researchers discovered that even after patients had recovered from Covid-19, they continued to have high levels of an inflammatory protein known as cytokines - produced by immune cells to activate an immune response against pathogens - even in absence of virus.
7) “An unusually high number of immune cells, known as T-cells, were also present in the blood of recovered patients, thus suggesting that their immune response remains activated even after the virus is gone.
8) “Patients who have recovered from Covid-19 often have virus-specific T-cells in their bloodstream.

However, the heightened immune response could trigger the cytokines to attack the blood vessels, increasing the risk of blood clot formation.

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Eric Feigl-Ding

Eric Feigl-Ding Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @DrEricDing

17 Apr
SEQUENCING CLUES—#COVID19 spread on an international flight, in a hotel corridor and then to household contacts despite efforts to isolate & quarantine patients, New Zealand reports. Careful genomic tracing confirmed the spread among 9 patients.
cnn.com/travel/article…
2) “One of those infected had spent 14 days in quarantine after being evacuated on a chartered 747 jet from India to New Zealand last August and had tested negative twice.
Others were infected on flight, even though 1/3 full and passengers were spaced apart from one another.”
3) in Singapore, some travelers tested negative during quarantine and then through routine tests they were found to be positive—serological (antibody) test results were positive too. moh.gov.sg/news-highlight…
Read 6 tweets
17 Apr
Wow—$1.7 billion investment in fighting #COVID19 variants just announced by Biden Administration to help states and other jurisdictions more effectively fight these mutations—including $1 billion for ramping up gene sequencing! That’s 🇺🇸 leadership. 🧵
whitehouse.gov/briefing-room/… Image
2) “An essential component of the response to the emerging COVID-19 variants is increasing the country’s genomic sequencing — process by which COVID DNA is decoded and potentially deadly mutations in the virus are detected.”

Hear that BC 🇨🇦 health Chief @DrBonnieHenry? #bcpoli Image
3) Many places not sequencing enough. But some places like BC 🇨🇦 is refusing outright to sequence new cases regularly. Instead they will only do sparse background sequencing. Here was BC’s final sequencing report before regular sequencing stopped.
Read 9 tweets
17 Apr
CONFIRMED—the very infectious #P1 variant is cause of @Canucks outbreak, team’s general manager confirmed. He also said P1 variant is why its hockey players were hit harder than other NHL—the virus “buckled” & sickened many of the players #COVID19. 🧵 cbc.ca/news/canada/br… Image
2) “What was different with our situation is with the regular COVID it seemed that after 10 days players were ready to get back on the ice and start working out and performing," he said. "But we had players that when they did that, they still had symptoms."
3) Benning said the virus "buckled" some of the players, and that three or four regulars likely won't be ready when games resume.

Head coach Travis Green, who also contracted COVID-19, has yet to return to practices.
Read 9 tweets
17 Apr
HOTEL ROOM CROSS-INFECTION: Australia 🇦🇺 hotel outbreak suggests #COVID19 jumped between hotel rooms—7 returned travellers cases arriving from different countries at different times have same genetic sequence—likely jumped between neighboring hotel rooms.
theguardian.com/world/2021/apr… Image
2) “The seven cases came from two family groups who arrived from different countries on different days. They stayed in adjacent rooms on the 12th floor of the Adina Apartments Hotel at Sydney’s Town Hall.
3) “Staff who worked on the floor when the original case was believed to have been infectious – between 8 and 11 April – are self-isolating.”

It’s possible it was either transmitted via hotel staff or via the air.
Read 10 tweets
17 Apr
LEAKY BORDER—Despite pandemic “closing” the US/Canada border, 30,000 truck drivers continue to travel between 🇺🇸 & 🇨🇦 daily—and with **no mandatory #COVID19 testing** and **no quarantine requirements**. Let that sink in—30,000 truckers per day! Not safe.🧵 vpr.org/post/most-us-c… Image
2) On an average day, about 30,000 trucks roll across the U.S.-Canada border, carrying more than $1 billion in trade.

Truckers are exempt from any COVID testing rules. And the industry’s trucking association opposes any mandatory COVID test restrictions.🔥google.com/amp/s/cdllife.…
3) If we know air travelers brings #COVID19 cases between countries, why don’t truck drivers?!?! It makes no sense.

I get they are essential, but cmon, allowing 30,000 truckers to cross 🇺🇸 & 🇨🇦 border unfettered by no mandatory testing or quarantine is BEGGING FOR OUTBREAKS!
Read 7 tweets
16 Apr
Oh boy. “some scientists are increasingly concerned that, because of a quirk of our own biology, future iterations of vaccines might not always be quite as effective as they are today”—due to **imprinting**. And maybe worse if you had natural infection. 🧵
statnews.com/2021/04/16/nex…
2) “The concerns stem from a phenomenon that is known as imprinting, sometimes called original antigenic sin, which is believed to affect how we respond to some pathogens.”
3) “In short, when your body is introduced to a particular threat for the first time — either through infection or a vaccine — that encounter sets your immune system’s definition of that virus and what immune weapons it needs to detect and protect against it in the future.”
Read 12 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!

Follow Us on Twitter!