[Thread] 1. Just in from Wednesday's cabinet briefing:
* The #CovidVaccine roll-out is still scheduled to start on May 17.
* There are now 3 338 vaccination sites (a list with the names hasn't been released).
2. When will can we start to use the 31 million #JohnsonandJohnson jabs that we've bought and will the first 1 million (from Aspen in SA) still land this week? We don't know. Neither @SAHPRA1 (our regulator; it needs to authorise use) nor @healthZA have made an announcement.
3. What do we know? Sahpra has recommended that the Sisonke trial (it uses J&J jabs) should resume. But before that can happen, Sahpra has to approve new docs submitted by the researchers (the study has to adhere to new rules set by Sahpra, e.g. better screening for blood clots).
4. So when will the Sisonke trial resume? In a press release of 20 April, the researchers and SA Medical Research Council said "within a few days". TimesLive reports co-lead researcher Glenda Gray said: "Next week": bit.ly/3xb7Dsp
5. If Sahpra approves the Sisonke study researchers' documents, does that mean it's okay for our wider #Covid19 vaccine roll-out to go ahead as well or is there another process for that? We don't know. Neither @SAHPRA1 nor @healthZA have issued an explanation.
6. People of 60+ have started to register on the EVDS. What should non-SAs without a passport/asylum /refugee nr do? @healthZA's Anban Pillay: I don't have a clear answer. Fwd to my colleagues as we haven't been presented with this ...previously where a person had no form of ID.
7. What jabs will SA be using? So far, J&J and Pfizer (the last announcement said we'll get the first batch of Pfizer jabs in the week of May 5). But you won't be able to choose which jab you get. J&J will mostly go to rural areas and Pfizer to urban areas.
8. Who above 60 (this is part of phase 2 of our roll-out) will get a jab first? The oldest people. So, in theory, the EVDS will give the oldest people appointments first (you won't get a date of appointment until we have jabs and we know we can use them).
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[Thread] 1. Stravos Nicolaou (from Aspen and SA's vaccine oversight committee): Phase 2a (people of 60 and older) and Phase 1b (health workers getting commercial vaccines) of our roll-out will run concurrently.
2. Stravos Nicolaou: Soon, SA will significantly ramp up the number of people vaccinated per day. We'll do two things: open up many more vaccination sites than what the Sisonke study had and have many more deliveries of #CovidVaccines.
3. Stravos Nicolaou: SA's #CovidVaccine pipeline: In total we've procured 61 million vaccine doses: 31million J&J, 30 million Pfizer - they will arrive over the course of 2021. We also have 500 000 Pfizer doses coming from COVAX.
[Thread] 1. People in South Africa who are 60 years and older can register on the government's electronic vaccination system from 4pm today (it was announced at a press briefing this morning). bit.ly/32h0Kar
2. At this stage, the system will only allow you to register and not yet allocate you a site or date to get vaccinated at (because a vaccination date depends on when our first batch of vaccines arrives and when Sahpra makes an announcement about the resuming of J&J's roll-out).
3. #ZweliMkhize: What do you need to register online? Internet access (smart phone, tablet, computer), an ID or passport, a cell phone number (so the system can send you text messages re appointments) and if you have a medical aid, your med aid number/card.
[Thread] 1. #ZweliMkhize says there is no evidence that J&J is linked to blood clots. SA is pausing its roll-out as a precautionary measure to find out if there is something to be concerned about before we proceed.
2. Helen Rees (Sahpra's chair): Vaccine safety is always at the top of our list. In the case J&J, the nr of blood clot cases is very low: 6 cases out of almost 7 million vaccinated people in the US. We need to find out if the cases are accidental or linked to the jab.
3. Helen Rees: This process is called a causality assessment. It's normal to do with new jabs. Why? In trials, jabs are tested on 1000s of people. When you roll them out, millions of people get them. So there's a chance for side effects you didn't see in the trial to occur.
[Thread] 1. VACCINE ARRIVAL UPDATES: According to #ZweliMkhize, J&J has confirmed that just over 1 mil #CovidVaccines will be delivered to SA between 22 + 24 April. They will all come from the local Aspen plant (previously we only knew they'd arrive in the 3rd/4th wk of April).
2. #ZweliMkhize: The 2nd and 3rd J&J #CovidVaccine batches in May and June (900 000 per month) will come from Belgium (the first batch will come from Aspen in SA), so delivery will be more complex. We'll get an exact delivery date within the next 2 weeks.
3. #Pfizer 1st batch of #CovidVaccines is likely to arrive in April. Next week, Pfizer will tell SA how many doses + also a specific delivery date (if there are no payment glitches). #ZweliMkhize previously said we'll get 5.5 million doses between April + June.
[Thread] 1. The two jabs — #JohnsonandJohnson and #Pfizer — that SA will (so far) use in its national #CovidVaccine roll-out have now both been approved for use by our regulator, @SAHPRA1. So what now — when will you get your jab?
2. The next batch of J&J jabs (200 000) will arrive on 10 April. But these #CovidVaccines are for use in SA's Sisonke trial (our implementation study) and only #HealthWorkers can be vaccinated with them. They can’t be used for our wider, national roll-out.
3. Our 1st commercial batch — 1 million J&J jabs — will land in the 3rd/4th wk of April. The diffs between this batch + the Sisonke jabs: we’re paying for this batch + can use it outside of a research setting. The Sisonke jabs came for free but we can only use them for the study.
[Thread] 1. SA’s commercial #CovidVaccine roll-out will start in April, the government says. Which jabs will we use? For now, J&J (the same jabs used in the Sisonke implementation study) and Pfizer. We will also consider Moderna, but no deals yet.
2. Why are we using J&J + Pfizer? SA trials showed J&J works well against the new variant, #501YV2. Pfizer hasn’t been tested in SA, but lab tests suggest it has reduced efficacy @ 501Y.V2. But because the efficacy is high (95%), even the reduced efficacy will provide protection.
3. Have the jabs been approved for commercial use in SA? Pfizer received emergency use authorisation (called Section 21 approval in SA) in March. J&J has not yet been approved (only for research), but on Monday @SAHPRA1 said an announcement will be made “within the next days”.