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Kevin K. Chung, MD

24 Apr, 10 tweets, 5 min read

A Multicenter Evaluation of Blood Purification with Seraph 100 Microbind Affinity Blood Filter for the Treatment of Severe COVID-19: A Preliminary Report

medrxiv.org/content/10.110…

#COVID19 #PURIFY #MedTwitter

After adjusting for covariates, treatment with Seraph 100 decreased the Odds of death [OR 0.27, 95% CI 0.09-0.79, p=0.016].

#COVID19

Of the 53 Seraph 100 patients included in the analysis, 1 patient experienced transient hypotension at the start of the treatment which required a brief period of vasopressor support.

#COVID19

These data suggest that broad spectrum, pathogen agnostic, extracorporeal blood purification therapies can be safely and effectively deployed to meet new pathogen threats as an adjunct to standard treatments while awaiting pharmacologic therapies and/or vaccines.

#COVID19

Final report of entire #PURIFY Seraph 100 cohort (n > 150) along with additional 30 prospective patients with viral load data coming in a few months.

#COVID19

@USUhealthsci

#Feasibility RCT for non-COVID for the indication of septic shock (with and identifiable pathogen) coming soon.

#COVID19
@USUhealthsci
@HJFMilMed

@60Minutes

This was featured in @60Minutes last week.

@SamHornblower

https://twitter.com/DrEricDing/status/1381456817595822081

@DARPA

Thanks to @DARPA for funding #DLT program that got this concept off the ground.

Supplementary files found here. 👇🏼

medrxiv.org/content/10.110…

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More from @chungk1031

Kevin K. Chung, MD

@chungk1031

22 Apr

@USUhealthsci

Looking forward to welcoming Dr. Kari Nadeau to our next #USUMEDSeminar!

Feel free to Join us as always.

ZOOM Webinar: usuhs.zoom.us/j/92051022987

@USUhealthsci
@pwhickey

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Kevin K. Chung, MD

@chungk1031

23 Dec 20

Dealing with dying patients.

#MedTwitter

A 🧵

I was prepping for a panel discussion with medical students on death and dying. Had to get some thoughts together based on my experience as a military intensivist so I thought I would share.

I’ve experienced my share of death. Of course the typical “taking terminal patients through the dying process” kind of stuff that every internist and intensivist deals with…

Read 13 tweets

Kevin K. Chung, MD

@chungk1031

22 May 20

How to get #verified.

A thread/

I am not an expert by any means.

But it took me 4 tries.

Each time I adjusted something that I think got me closer.

I thought I would share a few insights about how I think I got #verified so you can also.

2/

@verified

Why?

The power of this platform is undeniable.

Now more than ever, the voices of our collective expert medical community needs amplification.

Too many out there remain #notverified who should be.

⬆️ @verified science/medical experts = defeat misinformation

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Kevin K. Chung, MD

@chungk1031

12 May 20

I am giving a talk on "SARS-CoV-2 testing and Immunity" this week. Thought it would make a good #Tweetorial.

Thread/

First testing.

You can categorize testing as follows:

✅Pathogen based (test for presence of virus)

✅Host based (test for patient's response)

There have been a LOT of Emergency Use Authorizations granted by the FDA. For a variety of tests.

Read 18 tweets

Kevin K. Chung, MD

@chungk1031

2 May 20

@MarkHoofnagle

I just saw this thread by @MarkHoofnagle and feel compelled to respond to clarify some things.

Disclaimers: I am not an ID expert. I am a Medical Intensivist in the Military. These are not the official views of the DoD. Just my personal opinions. No financial COIs.

1/

https://twitter.com/MarkHoofnagle/status/1256242036015063042

I have participated only as a site-AI but I have participated in investigator meetings since the inception of this trial so I have *some* inside knowledge.

2/

First off, this trial was conceived and protocol approved before our very first US case back in February. It is funded by NIAID. Not Gilead. Remdesivir was chosen because of its potential. Not financially motivated.

Full info here. 👇

clinicaltrials.gov/ct2/show/NCT04…

Read 19 tweets

Kevin K. Chung, MD

@chungk1031

3 Apr 20

Dear Healthcare Leader (at every level),

The longer this drags on, the tougher it is going to get and the more people will need you.

People have asked, what can I do to maintain morale through this difficult time?

1/

You know what every great commanding general does in the midst of battle to help boost morale?

They show up.

On the front line.

Despite the danger, bullets flying, etc.

2/

Take a page out of the military leadership playbook.

Show up to the COVID units.

Show that you are willing to face the same dangers that everyone else is facing daily.

3/

Read 6 tweets

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