thelancet.com/journals/lance…
SARS-CoV-2 elimination, not mitigation, creates best outcomes for health, the economy, and civil liberties.
Public health, economic growth, democratic solidarity, and civil liberties are important factors when evaluating pandemic responses. There is mounting evidence that these objectives do not need to be in conflict in the COVID-19 response.
Countries that consistently aim for elimination—ie, maximum action to control SARS-CoV-2 and stop community transmission —have fared better than countries that opt for mitigation. (ie, action increased in a stepwise way to reduce cases so as not to overwhelm health-care systems)
There is also increasing consensus that elimination is preferable to mitigation in relation to a country's economic performance.
Elimination is superior to mitigation for GDP growth on average and at almost all time periods.
Despite advantages, elimination strategy has been criticised for restricting civil liberties. This claim can be challenged by analysing the stringency index developed Oxford. The index measures the strictness of lockdown-style policies that primarily restrict people's behaviour.
Among OECD countries, liberties were most severely impacted in those that chose mitigation, whereas swift lockdown measures were less strict and of shorter duration.
Evidence suggests that countries that opt for rapid action to eliminate SARS-CoV-2—with the strong support of their inhabitants—also better protect their economies and minimise restrictions on civil liberties compared with those that strive for mitigation.
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Scientific consensus on the #COVID19 pandemic: we need to act now.
One look at the authors list, and you'll see thought leaders in their fields; working diligently and with scientific evidence to make a difference.
"Just facts" in here, nothing else. thelancet.com/lancet/article…
The #herdimmunity approach is a dangerous fallacy unsupported by the scientific evidence
The Barrington Declaration for focussed protection towards herd immunity has no basis in science and evidence. Full stop. It is a misguided self-aggrandising document, similar to the one circulating with patient zero at the White House.
We have technical resources, we have scientific expertise, we have diversity in our experiences- @rivm and #OMT should consider using all the help they can. @C19RedTeam has offered their cross-functional expertise. A pandemic isn't just a medical issue, it is a societal issue.
Rather than rejecting any/all collaboration, @rivm and #OMT (for all their excellence) need to be inclusive, swallow their pride and open up.
All the evidence that they have made their recommendations on, needs to be in public domain.
Have we misjudged the role of children in spreading #COVID19?
COVID19 research in to kid, especially younger ones, is not perfect. It has gaps, it is evolving and we are learning more by the day.
A short summary of evolving role of children 👇 cmaj.ca/content/192/38…
Statement from Ontario’s science advisory table:
- Kids may play a bigger role in the spread of #SARSCoV2 than initially suspected.
- Early suggestions that children are considerably less important drivers of transmission are not confirmed by more recent research.
Children less susceptible? 1. Contact tracing studies reported that children<10 years old are less likely to test positive.
Limitations: Studies underestimate infection rate in children if infected children are more likely to be asymptomatic than infected adults.
@IHME_UW (Institute for Health Metrics and Evaluation) and @UWMedicine (University of Washington’s School of Medicine), no lightweights, have come out with
global projections of #COVID19 by nation.
Short summary 👇
They modelled 3 scenarios: 1. Worse case:
- mask usage stays at current rates, and,
- governments continue relaxing social distancing requirements.
This leads to 4.0 million total deaths by the end of the year.
Best case:
- mask usage is near-universal, and,
- governments impose social distancing requirements when their daily death rate exceeds 8 per million.
This leads to 2.0 million total deaths if by the end of the year.
Huge respect for Aura but some of her responses are contentious. I thank her for the work that she and her team are doing in this ever developing #covid19 pandemic. But one didn't need to understand #coronavirus to implement certain rules. volkskrant.nl/ts-b73f5cef
Question: Maar anderzijds had u ook best kunnen adviseren: bescherm jezelf nou maar, voor de zekerheid.
Aura: Zeker. Maar dat is met de kennis van nu. Wat we in maart, april dachten te weten over het virus is achterhaald door de snelheid waarmee het zich bleek te verspreiden.
Has any of the field epidemiologists been involved in the decision making, they would have insisted on PPE/masks in healthcare/nursing homes.
Crisis management experts would have insisted it is better safe than sorry.
A descriptive analysis of existing literature presented a #SARSCoV2 risk-chart from asymptomatic people in different settings and for different occupation times.
Lead authors (@trishgreenhalgh) noted that this is an indicative table; and not quantitative or predictive.
Great overview of occupancy (indoors/outdoors), ventilation (well/poorly), type and level of group activity (silent, speaking, shouting), time duration and face coverings --> and risk of #SARSCoV2 transmission.
Variation in susceptibility, viral shedding rates were not looked at.
An indicative, traffic-light like chart for an overview of transmission risk. Other take home messages: 1. Distribution of viral particles affected by air flow too. 2. #SARSCoV2 may travel >2m through coughing,shouting. 3. Rules should reflect ventilation,occupancy,exposure time.