It’s gonna be a slow crawl to 70% vaccinated. But we can get there. Let’s do this. 💪🏼 #COVID19 #vaccinate
2) Thank you @BillBramhall for the excellent cartoon!
3) Tucker Carlson is NOT helping damnit. But @iamjohnoliver is.
5) Here is where vaccine uptake is the highest and lowest per capita. We have a lot further to go in many places.
6) Vaccine hesitancy is a real problem. In the Deep South and in Idaho and Montana.
7) the reason we are worried now about uptake is that vaccines administered per day is dropping fast. We will soon be below 2 million shots per day again.
8) That J&J pause… ouch.
9) Seriously, that J&J pause was a serious factor. But the drop overall even in the other vaccines a problem now too. nytimes.com/interactive/20…
10) Vaccine conversion is now the key.
11) that said, it’s hard to get past 65%… Israel having trouble now too.
12) Bring on the financial incentives if necessary. It might be. But there will be a fairness issue to address for those already vaccinated.
15) Good story with lessons how to convince a vaccine skeptic friend.
16) we might need to require vaccines for super high risk / high exposure occupations.
17) listen to one of the most renowned epidemic experts in the word, @rajpanjabi, who has run global health programs for decades, when it comes to mass vaccination programs.
18) We have so much vaccine privilege in America— the rest of the world 🌍 is begging for the vaccine supply that we have. Let’s be grateful.

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More from @DrEricDing

6 May
I cry for India: “Those who are lucky will survive—whoever has to die will die”.

Hidden camera of 🇮🇳 hospital: horrible ICU conditions, shortages, long lines of sick. @BBC follows a family that lost a 35-year old mother of 2.

HT @yogital @NicolaCareem
2) Rundown hospital “conditions the government doesn’t want people to see. So we filmed secretly. Covid patients being treated amid other illnesses, cared for by their own family.” With toilets overrun in ICU. Image
3) “the people here are angry. The PM @narendramodi makes announcements on TV, but nothing reaches us”. Image
Read 9 tweets
6 May
⚠️Don’t ignore—

"Ignoring variants today, suggesting they aren't important, leads us to ignore variants tomorrow.

Ignoring the variants of tomorrow is potentially a f***ing big mistake!"

…says Dr. @michaelmina_lab,
Harvard immunologist & epidemiologist
#COVID19 #vaccinate #P1 ImageImage
2) “variants are extremely concerning. Most data at this point shows anywhere from a 10-fold to a 30-fold reduction in nAb against the variants”
3) “When we mix these variants with elderly immune systems that will wane - we will see new cases emerge amongst fully vaccinated vulnerable in our communities this year. it will be bad in this fall and it will lead to outbreaks and deaths again.” 🔥
Read 5 tweets
6 May
Insulin was invented ~100 years ago, and its patent sold for $1.

“Do you know the reason why [insulin is] $1,000 with insurance?” ~@AOC

There is no reason for insulin to cost $21 in Canada for a 10 ml bottle, while it costs a mortgage payment in the US.
2) atrocious amount of big pharma price gouging on insulin. Absolutely atrocious. Heartbreaking atrocious. Shamefully atrocious.
3) Let this sink in:

In 2018:
J&J CEO made $30M
Pfizer CEO made $28M
Merck CEO made $18M
Eli Lilly CEO made $16M
Gilead CEO made $16M

While:

📌Americans spent $535B on Rx drugs

📌1/4 of diabetics rationed insulin to survive

📌500K Americans went bankrupt from medical bills.
Read 10 tweets
6 May
📍GET BOTH DOSES! Great variants & #COVID19 vaccine news—Pfizer/BioNTech vaccine had great efficacy of 89.5% vs #B117 🇬🇧 variant & 75% vs #B1351 🇿🇦 variant for infection—but only with 2 doses. The 1 dose efficacy was just ~29% vs #B117 & ~17% vs #B1351. 🧵
nejm.org/doi/full/10.10… Image
2) “Viral genome sequencing conducted from February 23 through March 18 indicated that 50.0% of cases of Covid-19 in Qatar were caused by B.1.351 and 44.5% were caused by B.1.1.7. Nearly all cases in which virus was sequenced after March 7 were caused by either #B1351 or #B117.”
3) To be clear—this was not a trial, but an observational case-control study. “Vaccine effectiveness was estimated with a test-negative case–control study design, a preferred design for assessing vaccine effectiveness against influenza (see the Supplementary Appendix).”
Read 7 tweets
5 May
Joe Biden waived the vaccine patents in the 4th month of his presidency. Donald Trump would not have waived the patents if he was President for another 4 years, 4 decades, or 4 centuries. Elections matter.
2) Biden’s trade ambassador has begun the process of waiving the patents. It will take time, but it’s coming.
3) Let this sink in—Trump WH actually moved to block efforts to waive the vaccine patents in October 2020!!! So damn straight Trump would have kept blocking it. washingtonpost.com/health/2021/05…
Read 4 tweets
5 May
📍VARIANT TAILORED VACCINE—Moderna announced that a variant-tailored 3rd dose of the NIH-Moderna vaccine greatly boosted antibody levels in volunteers in a new study. The updated vaccine, tailored against the #B1351 variant from 🇿🇦, worked best.🧵 #COVID19 businessinsider.com/modernas-boost… Image
2) Earlier research, done in petri dishes, suggested the B.1.351 variant was able to partially reduce the effectiveness of leading vaccines, including from Pfizer and Moderna. businessinsider.com/coronavirus-va…
3) How much did the #B1351 variant decrease neutralization from Pfizer and Moderna vaccines? A lot. 20-30x fold drop for Moderna. And 30-40x fold drop for Pfizer - akin to a completely unrelated distant bat coronavirus. While not equal to efficacy, this is a big drop. See 🧵
Read 9 tweets

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