Tweet

This Thread may be Removed Anytime!

Twitter may remove this content at anytime! Save it as PDF for later use!

More from @ck_eternity_

CK Eternity

@ck_eternity_

3 May

The idea that cultures that use entheogens for the purpose of religious experience or enlightenment are not practicing "real spirituality" couldn't be further from the truth

All religion has roots in shamanism, it's only in more recent history that other religions have replaced shamanism with non-psychoactive sacraments

This is an excellent lecture that expands on this point:

There's nothing wrong with any religion, with or without the use of substances, all can provide genuine religious experience

The issue we're seeing in Western society is that because the experience of shamanism isn't available, it has been co-opted out as a tourist attraction

Read 5 tweets

CK Eternity

@ck_eternity_

3 May

Ultra low dose naltrexone (ULDN)

(thread)

For a few months now I've been experimenting with microdoses of naltrexone, an opioid receptor antagonist

I'd like to unpack some of the benefits I've noticed and the most likely mechanisms through which it works

Naltrexone works through two primary mechanisms

1. antagonizing (inhibiting) the opioid receptors, most potently the mu opioid receptors which are responsible for the euphoria and pain relief from opiates and endorphins

Read 19 tweets

CK Eternity

@ck_eternity_

1 May

https://twitter.com/DrJackKruse/status/1388115204286844934

This is also why algae oil DHA isn't a proper replacement for omega-3 from seafood

DHA from seafood is already preformed in the SN-2 position, which impacts both its bioavailability and use in the brain and eyes

https://twitter.com/DrJackKruse/status/1388115204286844934

Make sure to opt for fresh or frozen seafood over canned, and stick to lower temp cooking over things like frying

High temps or poor storage can oxidize DHA causing it to lose the symmetrical electron configuration that allows it to act as a quantum semiconductor

I'd avoid fish oil for the same reason, it's mostly low quality and a marketing gimmick

All the same omega-3 fats are found in fish and shellfish, with loads of added nutrient content as well

Read 5 tweets

CK Eternity

@ck_eternity_

28 Apr

There's an interesting divergence between what allows humans to function better in the short term vs. the long term

We see decreased longevity with increase calorie consumption and more animal products, but better exercise performance and nutrient status at the same time

From an evolutionary fitness perspective optimal health only needs to extend up to or slightly beyond reproductive age, so even an ancestral diet isn't guaranteed to provide benefit far beyond that point

That said, there do seem to be some principles that overlap

For example, nutrient deficiency has been robustly linked to a variety of short and long term health issues and symptoms

I think it's best to target the basics like this first, then progress toward the goal of longevity/disease prevention from there

Read 4 tweets

CK Eternity

@ck_eternity_

28 Apr

Carbohydrates aren't converted into fat unless they're consumed far above maintenance calories

That said, loading up glycogen stores can make it less likely that dietary fat will be used for energy as glycogen is the priority energy source

To put it simply: carbs and fat can both contribute to a caloric surplus which can result in weight gain either way, but of the two it is the dietary fat that's stored as it requires the least conversion

Processed carbs do still have several characteristics that make them more likely to cause caloric surplus in many cases

They are often found in overly palatable foods that are designed to be addictive, though in some cases (ie donuts) they are also combined with fat

Read 5 tweets

CK Eternity

@ck_eternity_

28 Apr

Methyl-B12, betaine, and SAMe all increase methylation by providing methyl groups for reactions, with methyl-B12 being the least potent, and SAMe being the most

Niacin decreases methylation by depleting methyl groups from the liver during metabolism, and increases acetylation

Folate is especially interesting as it dynamically regulates methylation, acting as a cofactor for methylation reactions in normal concentrations, while decreasing methylation downstream of its activity at the folate receptor when taken at higher doses

B6 is required to clear methyl waste, aka homocysteine, allowing it to be metabolized into useful cysteine, sulfate, and taurine

B2 is a cofactor for the metabolism synthetic folic/folinic acid from plant foods and supplements

Read 5 tweets

Share this page!

CK Eternity

Try unrolling a thread yourself!

More from @ck_eternity_

CK Eternity

CK Eternity

CK Eternity

CK Eternity

CK Eternity

CK Eternity

Did Thread Reader help you today?

Like this author's thread?