Indiana University Infectious Diseases Fellowship
10 May,
5 tweets, 3 min read
#idboardreview 18 M altered mental status, difficulty walking, urinary retention, sx progressive x4d. He had parotitis/orchitis 2wks ago. CSF150 wbc 100%mono ⬆️protein, gram stain/culture neg. mri leptomeningeal enhancement. Dx? #medEd #idmedEd #IDtwitter 
#mumps encephalitis nature.com/articles/31017…
In unimmunized pts: mumps is one of the most common causes of aseptic meningitis & encephalitis (cns involvement 10-30% of all mumps cases). 40-50% mumps meningitis have no parotitis. Males are affected 2-5x more than females. Peak age 5-9 yrs
#mumpss meningitis Defervescence usually accompanied by clinical recovery & in uncomplicated cases illness is 7-10d. Rarely, mumps may cause encephalitis, seizures, polyradiculitis, polyneuritis, cranial nerve palsies, myelitis, Guillain-Barré syndrome, and fatality.
#mumps meningitis csf wbc <500, >80% mono, normal protein half of pts, dec glucose in 25%. Complement fixation & hemagglutination inhibition in serum is reliable serology Dx.
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