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Eric Feigl-Ding Profile picture
@DrEricDing
May 13, 2021 • 14 tweets • 10 min read • Read on X
📍My god… the upgraded warning #B16172 variant (magenta) is surging so fast. Epidemiologists now estimate it is 60% faster than even #B117 UK/Kent variant, which is already 50% faster. If true, it could make it fastest transmission one to be found worldwide. Thread 🧵. #COVID19 Image
2) #B1672 has become quite dominant in India 🇮🇳 sequenced samples in @GISAID data. And it is projected to take over further by June. Figure from @TWenseleers.

Some say it could be due to sampling, but Tom doesn’t think so because #B16171 wouldn’t be selectively withheld. Image
3) @TWenseleers used his methods from earlier paper to estimate the new #B16172 transmission being 60% fast than the U.K. Kent #B117 variant.
4) the Brazilian #P1 variant m, despite being 2x faster than original strain, would be actually slower than the #B16172 if put into head to heads transmission competition.
5) And now #B16172 is surging in the UK too. Someone poke Boris Johnson to wake up.
6) the new UK data on #B16172 surge from @sangerinstitute is reliable because it excludes travel sequenced cases and excludes screening.

UK data even suggested #B16172 could even by 2x faster (not just 60% faster from India 🇮🇳 data above) than the #B117!! Wow. 👀
7) The World Health Organization said that the coronavirus variant first identified in India last year is being classified as a variant of global concern, with some preliminary studies showing that it spreads more easily

8) Its surging across UK. #B16172 is the new variant that we faced with in addition to #P1.
9) #B1617 lineages are surging worldwide.

Nobody is safe until we are all vaccinate.
10) surging even in wealthy Singapore
11) To be clear, we think the #B16172 Indian VOC may be ~2.6x as fast as original strain, and 60% faster than #B117 from UK/Kent. #P1 is thought to be 2-2.5, but we haven’t seen P1 and B16172 sufficiently together in same place yet in a head to head comparison to know for sure.
12) yes the US has more vaccines than India. But we are seeing #B16172 rise even with high vaccinations in the UK. And again, not all vaxxed.

also THINK OF THE KIDS… tens of millions of kids aren’t vaccinated or even eligible yet… cough… #LongCovid @LongCovidKids… cough.
13) India variant #B16172 in the UK. Anything out of the ordinary? No? Move along.

(Ht @Dr_D_Robertson ) Image
14) Bad news from UK 🇬🇧 SAGE govt report on the #B16172. It’s blazing fast. https://t.co/m36AINf9oO

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More from @DrEricDing

Eric Feigl-Ding Profile picture
May 6
Very worried—“The virus may soon develop the ability to transmit from one human to another… This is of great concern. Earlier birds… then it started affecting mammals and now the virus has evolved and developed the ability to infect humans…” @WHO Farrar
2) “We have to make sure that the H5N1 does not come across humans as it can easily develop the ability to transmit between humans.”
3) Last year, scientists warned of a key mutation that would help supercharge human transmission down the road — the critical “E627K” mutation in the virus’s RNA polymerase PB2 gene. ➡️Well, guess what effing appeared in a CDC report for the first time last month in an infected Texas man? ⚠️That very goddamn E627K mutation! This is mammalian adaptation. This is why WHO is warning we are maybe approaching the brink of human adaptation.

(Warning article about E627K from 2023).


(CDC report from April 2024).
science.org/content/articl…
cdc.gov/flu/avianflu/s…Image
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Read 7 tweets
Eric Feigl-Ding Profile picture
May 5
💔HEARTBREAKING—These twins need a $4.2 million one-time drug to save their lives (Spinal muscular atrophy). Their mother’s health insurance (and her employer) @Mosaic_LifeCare conveniently told the family the drug was cut from their coverage precisely one day after they were born. Total coincidence, my ass.

It’s also a race against the clock to get the treatment Zolgensma for the twins before it’s too late. If Zolgensma is given soon after birth, children may develop no significant disabilities. Children who receive the drug when they are a little older may avoid a feeding or breathing tube, and capable of some movement, rather than a life spent immobile, or death (<2 years usually), if not treated.

Zolgensma is sold by @Novartis. The drug sells for $1 million in Brazil, but $2.1 million in the U.S. Also in Brazil, if the child dies of SMA disease within 4 years, part of the $1 million payment is waived. But not in America. Many patients have had to sue health insurance to get the treatment covered—often at the expense of further disability of the untreated child.

All this is further enrage, when in fact, federally funded NIH research contributed to the development of Zolgensma. ➡️READ: Taxpayer dollars helped create the drug. Now the public is being shafted.



There is a GoFundme but this shouldn’t be the long term solution for other families. @Mosaic_LifeCare & @Novartis both need to be help accountable.


wbtv.com/2024/04/30/new…
gofundme.com/f/eli-easton-r…
durbin.senate.gov/newsroom/press…Image
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2) how can drug makers dare charge so much? Because they can - it is the only treatment and the only cure. I always remind people that healthcare is a NEED (like air and water) and not a “want” (like a fancy widget) If there is a monopoly, they can extort you if it’s a NEED.
3) Free market people will try to trick you into thinking it’s just the “supply and demand” / “free market” at work. But that’s only works for things in which there is no monopoly, and for things like iPhones and fancy gadgets “wants” that you can simply pass up if too costly. But if it’s a NEED—like lifesaving treatment—(eg you will pay anything to save your child / family member’s life)—then the supply & demand curve COMPLETELY BREAKS DOWN and is invalid. Big pharma and PBMs and your hospitals & health insurance premiums all exploit that in different ways. Don’t fall for “free market” bullshit that doesn’t apply to critical lifesaving healthcare.
Read 5 tweets
Eric Feigl-Ding Profile picture
May 2
Incredibly frustrating that the @USDA again failed to include basic information about H5N1 genetic sequences from cows. All data had dates and locations scrubbed out—only saying “USA” & “2024”, which is useless for scientists to analyze for mutation rates.
statnews.com/2024/05/02/bir…
Image
2) The fact that basic information — called metadata — isn’t being shared about the samples “hinders our efforts a lot,” said Gytis Dudas, a senior researcher in genomic epidemiology and metagenomics. Dudas is working with a group of U.S. and international researchers to try to make sense of what the genetic sequences say about the H5N1 outbreak in cows.
3) A number of scientists have openly questioned whether the USDA is deliberately withholding these data, or even removing more specific information. 🔥
Read 5 tweets
Eric Feigl-Ding Profile picture
Apr 27
⚠️CDC WARNING FOR ALL VETERINARIANS, POULTRY, DAIRY & CATTLE FARMWORKERS, SLAUGHTERHOUSE WORKERS—New CDC guidelines now released to use PPE for high risk bird flu exposure occupations (all recommended):

📌N95 respirators
📌Goggles 🥽 or face shield 🛡️
📌Coveralls or fluid-resistant aprons
📌Head covering
📌Rubber boots with sealed seams
📌Gloves

Furthermore:
📍Designated areas for changing PPEs
📍Do not eat, drink, chew gum, chew tobacco, smoke, vape, or use the bathroom while wearing above PPE
📍Shower after work shift
📍(see full list for more details).

Glad the @CDCgov is taking this seriously. You should too. And please don’t drink raw milk 🥛! #AvianFlu #BirdFlu #H5N1
cdc.gov/flu/avianflu/h…Image
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Don’t do raw milk 🥛 please, for the love of god. I know there are many raw milk enthusiasts out there. But just take a pause until this is over? Don’t try to be a macho man about this.
3) try to drink either vegan milks like oat or soy or almond milk, or ultra pasteurized milk.
Read 9 tweets
Eric Feigl-Ding Profile picture
Apr 27
Seriously. Raw milk drinkers… don’t do it. We scientists are pretty damn sure there will be some degree of active virus inside raw milk. Cats have been infected on farms—via likely raw milk. And all 6 cats with bird flu have died of rapid neurological declines, says CDC.
Raw milk drinkers… 1% of all milk being non pasteurized worries me. Too much virus to be potentially circulating.
3) I’m sticking with either vegan types of milk, or ultra pasteurized just to be safe.
Read 6 tweets
Eric Feigl-Ding Profile picture
Apr 26
⚠️Bad signal—CDC confirming—“cats having neurologic symptoms, rapid decline, and death” from H5N1 #birdflu. 3 more cases in cats 🐈 on dairy farms… now 6 total. ➡️The prior 3 bird flu positive cats? All dead now. Likely more. This is mammalian adaptation.
bnonews.com/index.php/2024…
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2) I suspect cats are drinking milk from the dairy cows on the dairy farms. This is why we shouldn’t drink raw milk 🥛 currently. Even pasteurized milk, some scientists are unsure of because of lack of safety data. See thread 🧵 below.
3) Not just cats — certain dog breeds (like beagles are highly susceptible to H5N1 avian flu too. And such dogs can facilitate their adaptation towards humans eventually (since more dogs are around people than dairy cows).

pubmed.ncbi.nlm.nih.gov/20580396/
Image
Read 10 tweets

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