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I'm not a Doctor & this is unverified but worth appreciating

#DRDO & their wonder drug for #COVID19

The Chemistry of Corona drug developed by DRDO is said to be a big game changer. It is 2-Deoxy-D+Glucose (2-DG) which is likely to be marketed very soon.

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The hero behind this discovery is said to be Dr Anil Kumar Mishra who hails from Balia (UP), obtained his MSc (Chemsitry) degree from Gorakhpur University in 1984 & PhD in 1988 from Banaras Hindu University. His research is based on Molecular Biology & Organic synthesis.

2/
After doing post doctoral research, he has worked as visiting Professor in different countries like France, California (USA) & Max Plank, Germany.

He joined DRDO as Sr Scientist in 1997.

2-DG is a mimic of D-Glucose prepared by replacing -OH group at C2 by H-atom.

3/
Hence, the name 2-Deoxy-D-Glucose meaning removal of oxygen from 2nd carbon. Being a mimic of D- Glucose, it gets easy passage into cells where Corona virus is present. Glucose breaks down into two 3-carbon compounds, 1 being pyruvate anion (CH3COCOO-) with release of energy.
4/
It is a metabolic process called Glycolysis. It is this energy on which all living organism survive. Corona virus also survives on this energy.

Unlike D-Glucose, 2-DG is unfit for glycolysis.No energy is evolved. The sustaining of life becomes difficult and as such

5/
Corona virus dies within a week for want of energy. Basically, the #ChineseVirus is fooled & then starved to death

This manifests as lowered oxygen dependence of patients.This drug is also antitumour/anticancer by the same mechanism.

6/
If it is able to destroy the killer Corona virus, precious lives will be saved.

Thank you DRDO!

Hopefully, mass-scale production is ramping up!

The principle of operation is simple: "Cheat the Cheater"! You know that any virus, once inside the body, makes its own copies by

7/
cheating our human cells & takes the body's own protein to multiply itself!

The brilliant thought process by Indian scientists was simple! For every doubling of virus cell, it needs energy (glucose!). So, the medicine is simply a "Pseudo" Glucose which the multiplying

8/
Virus intakes but actually, this glucose neuters it (unable to multiply!)

Thus, by "Cheating the cheater", the once rapidly multiplying virus is halted. Then, our own antibodies can readily combat it and overpower within hours!

Simple & elegantly effective.

Kudos DRDO 🙏

9/9

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