The Chemistry of Corona drug developed by DRDO is said to be a big game changer. It is 2-Deoxy-D+Glucose (2-DG) which is likely to be marketed very soon.
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The hero behind this discovery is said to be Dr Anil Kumar Mishra who hails from Balia (UP), obtained his MSc (Chemsitry) degree from Gorakhpur University in 1984 & PhD in 1988 from Banaras Hindu University. His research is based on Molecular Biology & Organic synthesis.
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After doing post doctoral research, he has worked as visiting Professor in different countries like France, California (USA) & Max Plank, Germany.
He joined DRDO as Sr Scientist in 1997.
2-DG is a mimic of D-Glucose prepared by replacing -OH group at C2 by H-atom.
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Hence, the name 2-Deoxy-D-Glucose meaning removal of oxygen from 2nd carbon. Being a mimic of D- Glucose, it gets easy passage into cells where Corona virus is present. Glucose breaks down into two 3-carbon compounds, 1 being pyruvate anion (CH3COCOO-) with release of energy.
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It is a metabolic process called Glycolysis. It is this energy on which all living organism survive. Corona virus also survives on this energy.
Unlike D-Glucose, 2-DG is unfit for glycolysis.No energy is evolved. The sustaining of life becomes difficult and as such
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Corona virus dies within a week for want of energy. Basically, the #ChineseVirus is fooled & then starved to death
This manifests as lowered oxygen dependence of patients.This drug is also antitumour/anticancer by the same mechanism.
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If it is able to destroy the killer Corona virus, precious lives will be saved.
Thank you DRDO!
Hopefully, mass-scale production is ramping up!
The principle of operation is simple: "Cheat the Cheater"! You know that any virus, once inside the body, makes its own copies by
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cheating our human cells & takes the body's own protein to multiply itself!
The brilliant thought process by Indian scientists was simple! For every doubling of virus cell, it needs energy (glucose!). So, the medicine is simply a "Pseudo" Glucose which the multiplying
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Virus intakes but actually, this glucose neuters it (unable to multiply!)
Thus, by "Cheating the cheater", the once rapidly multiplying virus is halted. Then, our own antibodies can readily combat it and overpower within hours!
Simple & elegantly effective.
Kudos DRDO 🙏
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It was Christmas eve of 2013 & God was fed up with the way mankind was evolving.
He took the tough decision of ending the human race & decided to inform the leaders. In a puff, @BarackObama , Vladmir Putin @KremlinRussia_E & India's very own #manmohansinghji
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appeared before him
He told them
"Hi! I'm God & I wanted you top leaders to carry my message to humanity. I'm fed up with your lies & deceit, so I'm ending the world."
& puff . . . . they were gone.
Obama reappeared at the White House where @MichelleObama & the girls were
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were decorating the Christmas tree. They wondered were he was gone but he didn't utter a word. Instead, he went to the Press Office & went live on TV & addressed the American people. He said
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A Teacher asked her young students to get their parents to tell them a story with a moral at the end of it.
The next day, the kids came back and 1 by 1, began to tell their stories
There were all the regular type of stuff till Janie said
''My daddy told me a
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story about my Mom
My Mom was a Marine pilot in Operation Desert Storm in Iraq and her plane got hit
She had to bail out over enemy territory & all she had was a flask of whiskey, a pistol & a survival knife
She drank the whiskey on the way down so the bottle wouldn't break &
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then her parachute landed her right in the middle of 20 Iraqi troops
She shot 15 of them with the pistol, until she ran out of bullets, killed 4 more with the knife, till the blade broke & then she killed the last Iraqi with her bare hands."
Thread alert
IMHO
Biggest achievements of #ModiSarkarKe7Saal we take for granted:
1 Self-attestation: In 1-stroke, no need to hunt for "Gazetted Officers" who will inspect an original document before imperially affixing a signature on a duplicate. Your word wasn't good enough
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2 Digilocker: Single tamper-proof repository of all your important documents. Excellent Govt service, use it if you don't
3 Fuel price deregulation: No need to wonder how much subsidy GoI will release, for which product, how it'll be financed, how will the finance be repaid?
4 C-forms: Part of GST rollout but needs an honourable mention as it was a nightmare for MSMEs. Issued on security paper (the same secure printing as a cheque leaf), no need for maintaining a register, keeping stock, indenting from the Dept & then politely chasing them for a few.
A man driving on the highway was stopped by the highway patrol
Cop: Do you know why I stopped you?
Man: Coz you're a Brahmin & this is #BrahminicalPatriarchy at work?
C: No! My caste has nothing to do with this. You're driving on the wrong side of the road
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M: I work for @Twitter & our community standards guide tells us we have to drive on the right side of the road
C: That guide was written in USA. You're now in India. You need to drive on the left
M: Though it's not the international standard, I'll strive to drive on the left
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C: No, no. If you drive on the wrong side I'll have to write up a ticket
M: Ok. I'll strive to drive on the left & tie up with India's opposition & NGOs to advocate we drive on the right. Can I go now?
C: I'm done! I'm writing a ticket
M: Now you're intimidating me! Fascist!
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Think about this & connect the dots
1 There's a growing feeling the #CCPVirus leaked from the lab & didn't jump from animals in Wuhan wet market.
2. If it was a deliberate leak, it makes more sense to experiment with the smaller & hostile Vietnam or the puppet State of
North Korea or even Taiwan & bring them to their knees. Even their long-pending invasion of Taiwan would have been possible.
3. But Wuhan (China's industrial heartland & pharma manufacturing hub) being the epicentre, shows it has to be accidental
4. Also, if the leak had been deliberate, China would have known EXACTLY what the next steps would be & wouldn't have been caught off-guard. They were lost & confused in the initial days. And, no. They weren't pretending.
@Mahesh10816@JumbuTweeple Typing as it comes, please bear with me:
The Bretton Woods system was created in the aftermath of WW2 by the winning allies. IMF, World Bank and the framework for the international monetary system was set up (favourable to the US).
Under this system, countries could print as
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@Mahesh10816@JumbuTweeple currency as they needed provided it was backed by assets, typically Gold, for it easily liquid and a store of value
This was called the Gold Standard. It meant that if you return $1000 to the US Fed, they would have to give you $1000 worth of Gold
Till Nixon became President
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@Mahesh10816@JumbuTweeple Under Nixon, it was suspected that the US was printing currency but not putting an equivalent amount of Gold into their reserves
The French got wind of this and started returning US$. This meant, at one point of time, the US would run out of Gold