Thread by @BooSoonYew67

Now food for thought.. there is a #yorkshirevariant variant "under observation" in the UK.. for a host of reasons.. #COVID19 #Covid19UK .. 1/n

https://twitter.com/SkyNews/status/1396189443871150082

Ignoring aside the parody abounding for this #yorkshirevariant .. The Science of it tells us that it has triple mutations; of concern because they involve 3 locations which had been reputed for nasty effects individually.. 2/n
google.com/amp/s/www.inde…

We take #mutation 1 of the #yorkshirevariant .. E484K , a spike protein mutation found in the South African & Brazilian variants, said to impact immune response.. 3/n
google.com/amp/s/www.inde…

Then #mutation 2 of the #yorkshirevariant .. the N439K , linked with immune escape, of concern in Scotland briefly last year.. 4/n
google.com/amp/s/www.inde…

Lastly #mutation 3 of the #yorkshirevariant .. the P681H , found in the Kent variant responsible for the high number of deaths last Jan + linked to greater transmissibility.. 5/n
google.com/amp/s/www.inde…

Morning @Shin63714105 .. #yorkshirevariant .. looks like UK is keeping an eye on it ..

https://twitter.com/BooSoonYew67/status/1396206862102499329?s=19

Morning Dr @gracehwang1970 .. I don't think there is any sign of #yorkshirevariant in #Korea , right ?

https://twitter.com/BooSoonYew67/status/1396206862102499329?s=19

@threadreaderapp .. unroll. Tq

More info in the P681H #mutation on the #SARSCoV2 .. very much more prevalent then in early 2021
news-medical.net/news/20210110/…

This time more info on the P681H #mutation of #SARSCoV2 in #NewYork ..
medrxiv.org/content/10.110…

This particular journal publication on P681H shows high prevalence in California, New York & Hawaii ..
medrxiv.org/content/10.110…

Now as for E484K #mutation .. this is a nasty one, shown to develop immune escape capabilities for the #SARSCoV2 !!
bmj.com/content/372/bm…

Reading the journal report on E484K #mutation .. can make you hold your breath to wonder what can come up next !!
bmj.com/content/372/bm…