Thread on the yawning gap between vaccine procurement and production
1. This is in the light of the Govt announcement on June 8 (VK Paul, head, Group on Vaccination) that the Govt is set to procure 770 million doses b/w Aug and Dec 2021.
2. To place the numbers in context: India has so far delivered about 235 m doses, of which about 90 % are Covishield. In April, the avg daily vaccination rate was 2.935 m, which dipped to 1.928 m/day in May - fall of 34% . Things improved in June, but not convincingly enough.
3. In the first 4 days of June the daily strike rate was almost 4 m doses but yesterday it was just 2.740, a drop of almost one-third. IOW, things look up but not convincingly enough.
4. The daily vaccination rate can be treated as a fairly accurate proxy of actual production of the two vaccine companies SII and BBIL. This is mainly because the Govt’s output numbers are neither reliable nor accurate.
5. So, while the massive procurement planned by the Govt in Aug-Dec is welcome, this by no means ensures supplies, especially for the quantities contracted for which the Govt says it has paid a 30% advance.
6. First, wrt SII. The Govt says it has contracted supplies of 250 m doses of Covishield. Incidentally @ of 50 m doses/month, this is what SII is supposed to be producing now. Hence, there is no sig expansion, unless its output is going to be exported in the days ahead.
7. 2nd, supplies of BBIL’s Covaxin are to amount to 190 m doses - @ of 38 m doses/month. We are expected that Covaxin supplies are to increase almost 4 times within 2-3 months. This is highly suspect.
8. Covaxin has been THE weak link in the Indian vaccine drive. BBIL has struggled to increase capacity and the NaMo Govt has failed to expand Covaxin production at more sites and by more producers.
9. 3rd, 300 m doses are to come from Biological E’s protein subunit vaccine, Corbevax. The Govt is reported to have paid an advance of Rs. 1500 crores, about Rs. 50 per shot. The technology is exciting because of the high immunity response it is reported to draw.
10. But not a single vaccine of this platform has been approved for use by major regulators anywhere in the world. Novavax (US) is the leading candidate in this race. Countries across the world have signed up for delivery of millions of its doses even before approval.
11. Corbevax is reported to be undergoing Phase 3 trials but between trials and initial production to scaled up full-tilt production is likely to be significantly longer than the window the Govt appears to want us believe. The problems of scaling capacity are too well known.
12. It thus appears that the flurry of announcements in last few days is aimed at lulling a restless population. The Govt’s moves suggest that it has attempted to counter one set of criticisms - that the NaMo Govt did not order enough vaccines from suppliers soon enough.
13. But ordering vaccines in a vaccine-starved world is meaningless if vaccine production is not going to actually increase. On that front, the NaMo Govt is still in slumber.
14. It has neither expanded Covaxin prod to other companies - private and PSUs - nor has it shown an urgency in putting an ecosystem for vaccine manufacturing.
15. We will have to wait till the end of June to see whether there is any meaningful, sustained and reliable increase in vaccine output. Until then NaMo’s vaccine strategy rests on a wing and a prayer. So will millions of Indians hoping to get vaccinated before Wave 3. (END)
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1. Most important takeaway: This is not a course correction. It is a mere amendment to the disastrous vaccine policy. Why do I say this?
2. The decision to provide “free” vaccines to states for 18-44 is welcome, but it comes with no intent to streamline vaccine distribution by making it dependent on objective, normative and verifiable standards. The arbitrary allocations to states will continue.
3. The only difference is that instead of a three-tiered pricing regime, there will be a two-tier pricing regime as 25 % of vaccine allocations will be to private sector. Already, how this is happening, and what prices are being charged is shrouded in opacity. This won’t change.
THREAD on BBIL’s saga of an incredibly spun yarn, based on its most recent release, today. 1. Starts with a treatise on vaccine making for the intellectually-challenged journalists - “complex and multifactorial process” with 100s of steps, it says.
2. Explains how the regulatory pathway is complex and takes time, effort, coordination with supply chains, etc. Generally, more fluff
3. Now comes to the real deal - that scaling production is a "step-by-step process". (BTW, what manufacturing process isn’t?). But here’s the innocently-couched punch: “There is a four-month lag time for COVAXIN to translate into actual vaccination.”
THREAD - on how companies mislead, and the media obliges obediently or unwittingly — the case of the elusive Covaxin shot. 1. As vaccine shortages, especially of Covaxin, mount across the country, BBIL issued a release y’day announcing a 200 m dose/annum expansion in capacity.
2. The benefit of the expanded capacity will become available by “Q4 2021”, it said. Preposterously, BBIL claimed that its capacity volumes would now exceed 1 billion doses. Now that is a lot of vaccines.
3. In comparison, Oxford-AZ’s entire planned planned global doses (incl from SII) for 2021 is 2.1 billion doses. Pfizer-BioNTech’s capacity is 3 billion, of which only 2.96 m doses remain available for the rest of 2021.
THREAD
On why the argument that India ought to have vaccinated its "own" people before supplying other countries is misplaced for several reasons. First, the vaccine manufactured by SII is subject to conditions from original funders (not GoI), Covax, the multilateral facility.
2. These orders pre-date the GoI's orders both in time and qty. The Covax facility provided funding to AstraZeneca/SII conditional on supplies, so there are contractual obligations. It is another matter that the NaMo Govt tried use it to fly the Vishwaguru flag.
3. There is simply no way SII’s obligations could have been avoided. So far, about 180 million doses have been delivered in India; about 66 m doses have been exported. Significantly, this 1/3 ratio (roughly) may be the division of supplies between domestic and exports in future
THREAD 1. On Serum Institute of India, which is among the highest profit margins in India, among companies with a turnover of over Rs. 5,000 crores (h/t @AnilKSood5 )
SII’s operating margin (operating profit/turnover) has NEVER fallen below 50 per cent ever since fiscal 2012!
2. SII is not a very large company - its total sales (2020) was just a little less than Rs. 6,000 crores. In comparison Tata Steel’s turnover was 1.4 lakh crores! But what is striking is its strike rate — its profit/turnover ratio.
3. In fact its average net profit margin (net profit/turnover) in the last decade has been about 44 %. Now, having enjoyed that kind of normal profit, one can sympathise with Poonawala when says he would like to make super profits!
THREAD 1. Here is an example of an external agency providing damage limitation services to the NaMo regime, which is struggling to explain its disastrous vaccination policy. orfonline.org/expert-speak/n…
2. Essentially, it ticks all the right boxes by extolling the virtues of the “largest” vaccination drive without neither respect for facts on the ground nor for the scale of the task at the hand of the Govt.
3. Instead, it asks that public “expectations” of a quick and comprehensive rollout should be “managed” and “toned down”. Now, that sounds sinister, doesn’t it? Basically, it says universal rollout of the vaccine is off the table.