Dear governments dealing with #DeltaVariant: Please heed these words by @DrMikeRyan from March 2020. ➡️ "Be fast, have no regrets. If you need to be right before you move, you will never win. the greatest error is not to move" & "speed trumps perfection".
2) With #DeltaVariant that can spread in just 5-10 seconds, can we honestly move slowly? I don’t think so. To twiddle our fingers and indecisively sit is to allow #DeltaVariant to build critical mass in the community. And once critical mass is established, hard to stop.
3) Low vaccination areas is a “time bomb waiting to happen” with #DeltaVariant says Dr @mtosterholm.

This #DeltaVariant surge will not end well for low vaccinations areas unless masks + other mitigation imposed. #COVID19

4) sometimes the precautionary principle is critical. Especially for the #DeltaVariant that spreads just so quickly. And vaccinated can still spread it, even if 2 dose vaccinated are protected.
5) This is what happens when you don’t react quickly to the #DeltaVariant. Infestation is hard to unroot once established. I’m starting to feel the #DeltaVariant spreads faster and insidiously like a Zerg swarm invasion.
6) wouldn’t it be wise for the CDC and MOHs of each country to take the precautionary principle and require masks again among the vaccinated when there are these kinds of data for 1 and 2 dose efficacy? Until 2x vaccinations over 85%, I’m not sure we can drop other mitigation.
7) Govts need to act quickly to contain #DeltaVariant — because it transmits very quickly according to Australia contract tracing investigations. Precautionary principle is critical.

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More from @DrEricDing

29 Jun
📍BREAKING—with #DeltaVariant now surging almost 50% of all #COVID19, Los Angeles County now "strongly recommends" everyone, **including folks fully vaccinated**, to wear masks indoors to curb the #Delta variant, especially when “you don’t know everyone’s vaccination status”. Image
2) This comes on the heels of the WHO recommending the same - that vaccinated people should still mask given then incredibly fast transmission of the #DeltaVariant and its unique severity.
3) In the UK, the #DeltaVariant is now nearly all cases, it is causing a 69% increase in cases in one week (just yesterday it was 58%), along with increasing hospitalizations and deaths.
Read 17 tweets
29 Jun
A third dose of the AstraZeneca vaccine can boost immune protection. In new trial, 3rd dose of AZ vaccine nearly seven months after first two shots—participants reported higher antibody levels after the third dose than a month after the second. #COVID19 🧵 nytimes.com/2021/06/28/wor…
2) The finding indicates that the AstraZeneca vaccine could be an option should third shots end up being needed, for example, to extend immunity. To date, the vaccine has been given as two doses, typically between four and 12 weeks apart.
3) The new data, detailed in a preprint manuscript that has not yet been peer reviewed, came from 90 study volunteers in 🇬🇧 who were among the earliest to receive the shots in a clinical trial. This past March, they were given a third dose, roughly 30 weeks after their second.
Read 4 tweets
28 Jun
A mixed schedule of vaccines where a shot of Pfizer #COVID19 vaccine is given four weeks after an AstraZeneca shot will produce better immune responses than giving another dose of AstraZeneca, an Oxford study said on Monday. 🧵 reuters.com/world/uk/immun…
2) study compared mixed two-dose schedules of Pfizer and AstraZeneca vaccines, and found they produced high concentrations of antibodies against the spike protein. The data provides support for the decision of some countries offering alternatives to AstraZeneca as a second shot
3) The highest antibody response was seen in people receiving two doses of Pfizer vaccine, with both mixed schedules producing better responses than two doses of AstraZeneca vaccine.
Read 6 tweets
28 Jun
Vaccines for pregnant women—@JohnsHopkins new dashboard reports 91 countries have policies that allow for at least some pregnant people to receive #COVID19 vaccines—45 of which broadly permit or recommend vaccines in pregnancy. But policies vary. 🧵 hub.jhu.edu/2021/06/28/tra… Image
2) "Data about COVID vaccines' safety for pregnant people and their offspring have generally been reassuring. But countries around the world have taken a variety of positions on COVID vaccination and pregnancy—ranging from highly restrictive policies that bar access to vaccines
3) “to permissive positions in which all pregnant or lactating people can receive vaccine and, in some cases, are recommended and encouraged to do so," said Ruth Karron, director of the Center for Immunization Research at the Johns Hopkins Bloomberg School of Public Health
Read 9 tweets
28 Jun
“I do not believe the virus was manmade.”

Dr Danielle Anderson, the Wuhan Institute of Virology's last foreign scientist, left in November 2019 just before #COVID19 pandemic. For the first time, she shares her story.
2) Anderson began collaborating with Wuhan researchers in 2016, when she was scientific director of the biosafety lab at Singapore’s Duke-NUS Medical School.

bloomberg.com/news/features/…
3) Her research—which focuses on why lethal viruses like Ebola and Nipah cause no disease in the bats in which they perpetually circulate—complemented studies underway at the Chinese institute, which offered funding to encourage international collaboration.
Read 12 tweets
28 Jun
📍New phase—“we're entering a new phase of this pandemic, with the more contagious #DeltaVariant” says AUS experts. First multi-region epidemic in 🇦🇺 in months. The escalation in #COVID19 has prompted lockdowns in Sydney and Darwin. Mask mandates too.
bbc.com/news/world-aus…
2) the #DeltaVariant is 2x more transmissible and 2.5-4x greater risk of hospitalization, and it is 1 dose vaccine evading. Australia 🇦🇺 is desperately trying to avoid a future fate of UK… where hospitalizations and deaths rapidly rising.
3) One dose is simply not enough. 18-30% is pretty darn low efficacy for #DeltaVariant infection. 2 dose please. Minimum. But even then with Delta, Pfizer drops to 79% and AZ to 60%. We need masks and mitigation on top.
Read 6 tweets

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