Dr Danielle Anderson, the Wuhan Institute of Virology's last foreign scientist, left in November 2019 just before #COVID19 pandemic. For the first time, she shares her story.
2) Anderson began collaborating with Wuhan researchers in 2016, when she was scientific director of the biosafety lab at Singapore’s Duke-NUS Medical School.
3) Her research—which focuses on why lethal viruses like Ebola and Nipah cause no disease in the bats in which they perpetually circulate—complemented studies underway at the Chinese institute, which offered funding to encourage international collaboration.
4) A rising star in the virology community, Anderson, 42, says her work on Ebola in Wuhan was the realization of a life-long career goal. Her favorite movie is “Outbreak,” 1995 film in which disease experts respond to a dangerous new virus—a job Anderson said she wanted to do.
5) Anderson was on the ground in Wuhan when experts believe the virus, now known as SARS-CoV-2, was beginning to spread. Daily visits for a period in late 2019 put her in close proximity to many others working at the 65-year-old research center.
6) She was part of a group that gathered each morning at the Chinese Academy of Sciences to catch a bus that shuttled them to the institute about 20 miles away.
As the sole foreigner, Anderson stood out, and she said the other researchers there looked out for her.
7) “We went to dinners together, lunches, we saw each other outside of the lab,” she said.
From her first visit before it formally opened in 2018, Anderson was impressed with the institute’s maximum biocontainment lab.
8) The concrete, bunker-style building has the highest biosafety designation, and requires air, water and waste to be filtered and sterilized before it leaves the facility. There were strict protocols and requirements aimed at containing the pathogens being studied, Anderson said
9) researchers underwent 45 hours of training to be certified to work independently in the lab.
The induction process required scientists to demonstrate their knowledge of containment procedures and their competency in wearing air-pressured suits.
10) “It’s very, very extensive,” Anderson said.
Entering & exiting the facility was a carefully choreographed endeavor. Departures were made especially intricate by a requirement to take both a chemical shower & a personal shower—the timings of which were precisely planned.
11) “These rules are mandatory across BSL-4 labs, though Anderson noted differences compared with similar facilities in Europe, 🇸🇬 and 🇦🇺. The Wuhan lab uses a bespoke method to make and monitor its disinfectants daily, a system Anderson was inspired to introduce in her own lab.
13) “She was connected via a headset to colleagues in the lab’s command center to enable constant communication and safety vigilance—steps designed to ensure nothing went awry.
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NEED MORE NUANCE—“Vaccines work” against the #DeltaVariant, yes—100% true. But it hides a lot of nuance—while vaccines protect YOU a lot if you get it, it will still allow virus to transmit & affect other susceptible—until hit higher vaxxed herd threshold (~85% for Delta)—Mask!🧵
2) key issue is that while you’re personally protected if 2-dose vaccinated (60% AZ & 79-88% Pfizer efficacy, 94% hospitalization), the much higher transmission (2x faster transmissibility than old) means a higher herd level needed to stop #DeltaVariant from hitting others.
3) Singapore Delta outbreak proves it—vaccinated still transmitted. In this #DeltaVariant cluster alone, among 29 vaccinated who were infected, 21 transmissions events were between vaccinated-to-vaccinated or vaccinated-to-unvaccinated. That is a lot!
Shocker—school mask mandates were rescinded for early teens in UK🇬🇧 on May 17th—#COVID19 cases rise. More shocker—schools close for holidays—cases fall. Even more shocking—cases rise again when schools reopen (with no masks). In other news, the sun☀️ also rises when 🌍 rotates.
2) Do we see this pattern with UK 🇬🇧 school #COVID19 absenteeism? Hell yes. Cases fall after holidays and soar again as school duration goes on.
3) Wearing masks should not be that hard especially to protect vulnerable kids who can’t get vaccines yet.
Fully vaccinated are recommended to wear masks indoors again (WHO & LA County). ➡️"The reason you're hearing about masks coming back is basically still to try and slow down the spread of what is clearly a more transmissible #DeltaVariant.” @drsanjaygupta🧵
2) This follows the move by WHO Senior scientists to recommend masks again to contain the spread of #DeltaVariant
3) Los Angeles county soon followed with their strong recommendation to mask indoors even if fully vaccinated. LA is now almost 50% #DeltaVariant#COVID19
All-time record high #COVID19 cases in Scotland 🏴—more than even this past winter surge. Furthermore, *hospitalizations and ICUs on the rise*. The #DeltaVariant is dominant in Scotland of course. Thread 🧵
2) Most of the surge in Scotland is among younger age groups. But it is increasing in the elderly as well, albeit more slowly. But most people over 45 are vaccinated yet cases still rising. It’s because of the #DeltaVariant
3) Scotland is slightly ahead of England in vaccinations. 🏴 is 49% fully vaccinated. Yet it still hit a record high #COVID19 caseload. Don’t anyone dare say that is near herd immunity threshold. It’s not even close damnit, especially with a higher R0 for #DeltaVariant of 6-8.
📍BREAKING—with #DeltaVariant now surging almost 50% of all #COVID19, Los Angeles County now "strongly recommends" everyone, **including folks fully vaccinated**, to wear masks indoors to curb the #Delta variant, especially when “you don’t know everyone’s vaccination status”.
2) This comes on the heels of the WHO recommending the same - that vaccinated people should still mask given then incredibly fast transmission of the #DeltaVariant and its unique severity.
3) In the UK, the #DeltaVariant is now nearly all cases, it is causing a 69% increase in cases in one week (just yesterday it was 58%), along with increasing hospitalizations and deaths.
A third dose of the AstraZeneca vaccine can boost immune protection. In new trial, 3rd dose of AZ vaccine nearly seven months after first two shots—participants reported higher antibody levels after the third dose than a month after the second. #COVID19 🧵 nytimes.com/2021/06/28/wor…
2) The finding indicates that the AstraZeneca vaccine could be an option should third shots end up being needed, for example, to extend immunity. To date, the vaccine has been given as two doses, typically between four and 12 weeks apart.
3) The new data, detailed in a preprint manuscript that has not yet been peer reviewed, came from 90 study volunteers in 🇬🇧 who were among the earliest to receive the shots in a clinical trial. This past March, they were given a third dose, roughly 30 weeks after their second.