Every day, I get emails from people who have noticed changes to their periods following the COVID vaccine. But we don't yet have enough information to know if this is really linked to the vaccine and, if so, how common it is. 2/
Since March, I have been saying "I'm sure someone is doing the kind of study that will find this out." I contacted some of the period tracking apps to see if they wanted to work with me on the kind of study that would find this out, but they weren't keen. 3/
A couple of weeks ago, I decided that I had to do something. So I have got approval from the University to run my own study. It's nowhere near as flash as it would be if I had worked with an app developer. But the important thing is: it's getting done. 4/
🗝️ Anti-COVID antibodies are present in breastmilk and would be predicted to be protective.
🗝️ Minimal transfer of vaccine mRNA.
More detail below... 🧵
The finding that anti-COVID antibodies make it into breast milk after vaccination is in line with findings from at least six other studies. Too many to post one by one, but you can find links to them here, under question 7.
@RealNormalPod@lisadunn1978 Great question! What you've just described there is called a "challenge study" and is sometimes done, eg for malaria vaccines. But in the case of COVID, since it's potentially fatal and there's no cure it was considered unethical. 1/
@RealNormalPod@lisadunn1978 In the trials, what they did was vaccinate half the participants and give the other half a placebo (either salt water or a different vaccine). Then they regularly tested everyone to see if the people who got the vaccine were less likely to get a positive test than the rest. 2/
@RealNormalPod@lisadunn1978 In fact, not all the trials did this. AZ did and Moderna sorta did but Pfizer only tested people when they got sick. This is why we spent some time when the vaccines were new going "we know it stops you getting sick, but we don't know if it stops you getting infected." 3/
What can vaccines on older platforms tell us about the side effects we might expect to see on the newer mRNA and adenovirus vector platforms? 🧵
This is something I’m asked a lot at the moment, particularly because people want to know if it’s fair to compare the menstrual effects seen with HPV and flu vaccines with those seen with COVID19 vaccines, as I have in this (now oldish) thread. 2/
A lot of people are asking me if #COVID19 mRNA #vaccines build up in the ovaries. This is an idea that seems to have come from some data submitted by Pfizer to the Japanese government.
But is it true? Let’s dive in!
(But TLDR: no...) 🧵
Here’s a machine-translated version of the document, so we can all see what’s going on. The document describes the outcome of two kinds of experiments. 2/
First, they administered a version of the vaccine that encodes a glowing protein, luciferase, to mice. This allows us to see where the vaccine is making protein because… well... it glows! Please enjoy the glowing mice. 3/
@beverleyturner@toadmeister To tackle your first tweet first. I think you are talking about the data submitted by Pfizer to the Japanese regulator? That Bryan Brindle has recently had a lot to say about? It's here... 1/
@beverleyturner@toadmeister First, it's important to note that Bridle (oops, I gave him an "n" above!) is not the inventor of these vaccines. He is actually working on a rival vaccine.
But in any case, a lot of what he says just isn't true. I talk more about this here... 2/
@beverleyturner@toadmeister It's also worth noting that the biodistribution data we're talking about here is radiolabelled lipids, not (necessarily) vaccine. 3/
@toadmeister Morning Toby! I’m the reproductive immunologist that is quoted in that Sunday Times article, here to provide a bit of context... 1/
@toadmeister The first thing to say is that Yellow Card is very good at detecting serious side effects that don’t usually happen in the absence of vaccination. That’s what it’s designed for and it’s one of the ways we were able to pick up the rare clotting side effect associated with AZ. 2/
@toadmeister What Yellow Card is not so good at is detecting a change in the rate of non-serious events that sometimes happen anyway. People experiencing a heavy period post-vaccine is a good example of such an event. 3/