Dr. Stephanie J. Galla 🦜🧬 Profile picture
Jul 20, 2021 11 tweets 10 min read Read on X
Check out our latest preprint: the relevance of pedigrees in the conservation genomics era bit.ly/3wCO7DH. TLDR: it’s not either/or when it comes to #pedigrees & #genomics. Having both helps researchers address more conservation questions than one data set alone. 🧵 1/10
Conservation #genetics 🧬 has developed a substantive toolbox 🔧 to inform species management. While much discussion has been dedicated towards genomic advances, there remains one long-standing tool in #ConGen that is often overlooked: the pedigree. 2/10
Pedigrees have been used to understand and manage diversity in threatened populations for decades. But, caveats like assumed founder relatedness, missing data, and errors can make them tricky to use. See Forsdick et al (ecoevorxiv.org/7bnjw/) for more. 3/10
Molecular data can address these caveats, and genomic data can provide similar estimates of relatedness to robust pedigrees, as explored in Galla et al. 2020 (bit.ly/2UuRizL). 4/10
But now that we can estimate relatedness with genomic data, some have asked whether pedigree data is worthwhile in the conservation genomics era. Here, we say YES. 5/10
In our paper (bit.ly/3wCO7DH), we describe how 🧬 data can reconstruct, complete, & validate pedigrees. Pedigrees can help with 🧬 study design & provide important life history, ecological & demographic context for quantitative genetic and genomic analyses. 6/10
Through perspectives from our practitioner & Indigenous coauthors conserving critically #endangered species in #Aotearoa NZ 🇳🇿, we contend that the act of building & sharing pedigrees can bridge gaps between researchers, practitioners, Indigenous Peoples & local communities. 7/10
Thanks to the team that contributed to this piece: @NamesAreHard89, Liz Brown, Yvette Couch-Lewis, Daryl Eason, @DrRebeccaMae, @jilla_hamilton, @JLEHeath, @SamanthaSHauser, Emily Latch, Marjorie Matocq, Anne Richardson, @birds_py, @HoggCarolyn, @ASanture, @testeeves. 8/10
We thank members of the Kākāpō, Kakī, and Kākāriki Karaka Recovery Programmes–incl the tribal representatives on the Recovery Groups for each of these taonga (treasured) species for their support. Thanks to @MBIEsci @docgovtnz @UCNZ #BrianMasonTrust #MohuaTrust for funding. 9/10
@threadreaderapp unroll, please!

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Dr. Stephanie J. Galla 🦜🧬

Dr. Stephanie J. Galla 🦜🧬 Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @sgalla32

Dec 13, 2021
Keen to hear more about the #SecretSauce to codeveloped #ConsGen DNA research/practitioner success? Check out our @SCBConGen symposium & roundtable @ICCB2021 🌍, 15 Dec 12-2PM EST. Presentations are already available online, for early viewing, and are fantastic! 1/n
Our six symposium speakers and roundtable panelists are representative of >6 countries 🇵🇹/🇺🇸,🇨🇱,🇦🇺,🇬🇧,🏴󠁧󠁢󠁳󠁣󠁴󠁿,🇿🇦,🇳🇿. Keen to learn more? check out their talks titles below. 2/n
Dr. Soraia Barbosa @soraiambarbosa from @CIBIO_InBIO will kick off the symposium with her talk "The importance of research-management partnerships to advance conservation practice and policy." 3/n Image
Read 8 tweets
Feb 4, 2020
We are excited to share our pub in #EvolutionaryApplications bit.ly/2GH3tzr comparing relatedness estimates for pairing recommendations in critically #endangered #birds from #Aotearoa #NZ 🇳🇿. See this #SciComm 🧵 for more! #Conservation #Genomics #ConGen #ConSERTeam 1/13
Around the 🌏, #conservation breeding programmes strategically pair the least related individuals to enhance recovery. This is like #Tinder for threatened species, only more information goes into pairing than swiping ⬅️ or ➡️. See my #3MT for more! 2/13

It’s important to get the relatedness value right for pairing, because mating between close relatives can result in negative fitness consequences, like ⬇️ hatching success 🐣(see bit.ly/3b4IILO). 3/13
Read 13 tweets
Jan 15, 2019
Exciting #ConSERTeam news! Our paper demonstrating the utility of closely-related reference genomes 🧬 for #conservation (Galla & Forsdick et al. 2019 @sgalla32 @NatForsdick @testeeves bit.ly/2Hj72z1) was published in @Genes_MDPI @MDPIOpenAccess. #ConGen 1/13
No longer just a promise (bit.ly/2SMXehV), the #ConservationGenomics revolution is here: #genomics is adding awesome tools to the #conservation tool box to inform the management of some of the world’s most threatened species. 2/13
One such tool is a reference #genome. Think of it as the picture of a completed puzzle on a puzzle box. Having a picture means genomic reads (puzzle pieces 🧩) can be placed correctly, allowing effective ID of SNPs (single nucleotide polymorphisms). 3/13
Read 13 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

:(