A very good look at how #Vaccination reduces mutation in #SARSCoV2 , the causative agent of #COVID19 !! .. 1/n
medrxiv.org/content/10.110…
Research was done on 2 prongs: First was by comparing data, analyzing over 1.8 million #SARSCoV2 genomes from 183 countries.. comparing to vaccination rates.. 2/n
medrxiv.org/content/10.110…
Results were remarkable !!
Definitely a decline in diversity of #SARSCoV2 lineage, coinciding with onset of mass #vaccination in countries !! .. 3/n
medrxiv.org/content/10.110…
Then a detailed look at how mutation is quantified.. by looking at Spike glycoprotein.. 4/n
medrxiv.org/content/10.110…
Now a very detailed genetic mapping of mutational frequency in known B-cell epitopes..

Note for Alpha, Beta, Gamma & Delta.. 5/n
medrxiv.org/content/10.110…
Remember the 2 prong approach of this study ? So after macro analysis of data.. now a micro level; comparing vaccinated & unvaccinated individuals..
Results validate the conclusion
But sample size is small:
vaccinated, n = 23
unvaccinated, n = 30 .. 6/n
medrxiv.org/content/10.110…
To cut a long story short..
Vaccinated individuals have LESS mutation of the virus, compared to unvaccinated ones !! .. 7/n
medrxiv.org/content/10.110…
So what take homes can we gather ?
1) For sure, with vaccination reducing mutation.. this will definitely reduce chance of future emergence of VOCs ..
2) Reducing mutation may make virus more susceptible to antibodies & reduce breakthrough infection in vaccinated individuals ..
@threadreaderapp .. unroll .. Tq

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More from @BooSoonYew67

22 Jul
New FFPP (Free Food for the People Project) today !! Image
Today #GrabBoo on duty .. Image
New FFPP (Free Food for the People Project) today, 23/7/2021.. delivery coming up !! 😁🚙 Image
Read 4 tweets
21 Jul
It tugs on your heart-strings.. 😢
The homeless..
who spend the night here..
Targetted Free Food for the Needy @ #Komtar #Penang ImageImage
This evening, those at #Komtar have Nasi Campur for dinner !! .. Targetted Free Food for the Needy.. #Penang .. 22/7/2021 Image
Morning 🌄 !!
Today from #Komtar .. refreshing sandwiches 🥪 !! Targetted Free Food for the Needy .. #Penang .. 23/7/2021.. 👍🏻👍🏻 ImageImage
Read 4 tweets
17 Jul
This is a very good & objective study showing that waning antibody levels in vaccinated individuals will be inevitable.. 1/n
thelancet.com/journals/lance…
The sample size is good.. n = 605, from participants in England & Wales.. 2/n
thelancet.com/journals/lance…
And the results..
A significant trend of declining S-antibody levels seen in BOTH ChAdOx1 & BNT162b2 #vaccines or the #AstraZeneca & #PfizerBiontech respectively.. 3/n
thelancet.com/journals/lance…
Read 10 tweets
17 Jul
Today's #FoodPack for Needy Families @ Cyberjaya .. 15 families .. #BenderaPutih #whiteflag .. Sat, 17th July 2021 .. Again those who wish to contribute can DM me. This project runs for a few days ahead ..
1/n
And #FoodPacks for Needy Families @ Cyberjaya .. ready to roll !!
#FoodPack packing done !!
.. #BenderaPutih for Needy Families @ Cyberjaya ..
Read 5 tweets
17 Jul
New FFPP today !!
Free Food for the People Project !! .. 😊🌞 #Penang
Food & Drinks on the road !!
🍛🥤 .. FFPP for Sat, 17th July 2021 ..
Another different preparation here.. for delivery to another location !! FFPP in #Penang on this Sat, 17th July 2021 .. 😁🤗😋
Read 4 tweets
16 Jul
It was a bright & sunny 🌞 Stage 19 of #TDF2021 .. and good commanding win by @matmohoric !! 👏🏻👏🏻👏🏻
The Yellow Jersey is firmly on @TamauPogi !! 👏🏻👏🏻
TQ @MaillotjauneLCL
Read 6 tweets

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