Mia Malan Profile picture
Jul 30, 2021 12 tweets 6 min read Read on X
[Thread] 1. How far are we behind with our original #VaccineRolloutSA targets? Dr Jabu Mtsweni from @CSIR has analysed this.

What is our target? To vaccinate 40 million adults in SA by March 2022.
2. How do we measure if we're reaching targets?
1. We can look at the nr of doses we administer in either a 5 (without weekends) or 7 day week
2. We can count how many people are fully vaccinated, but the nr of doses we count are different for JnJ (1 dose) and Pfizer (2 doses)
3. So how is SA doing?
1. Average nr of doses/day = 173 258
2. 80% of the doses = Pfizer (2 doses) and 20% = JnJ (Pfizer was up until recently, the only jab available to SA to roll out at sites)
3. Using more 2 dose jabs makes us move slower on targets for full vaccinations
4. Weekends show huge dips in vaccination numbers
* On weekends we've done an average of 26 000 jabs/day (compared to 173 258 on weekdays)
* Gauteng leads in terms of weekday numbers (66 000 per day)
* NC has done the fewest vaccinations (3 776 per day)
5. How many jabs do we need to do/day to reach targets (64.6 mil more jabs by March)?
1. To reach 40 mil people by 31 March (if we do vaccinations 7 days per week): 264 000 jabs/day
2. To reach 40 mil people by 31 March (if we do vaccinations 5 days per week): 369 000 jabs/day
6. If we assume that 15% of the 40 mil adults we'd like to vaccinate, will choose to not be vaccinated, then we'd have to administer another 54.9 mil doses by 31 March, so our targets would be lower:

1. 223k jabs per day (for a 7 day wk)
2. 313 k per day (for a 5 day wk)
7. So is 250 000+ jabs per day a realistic target? Yes, based on what countries with similar populations to SA (SA pop = 60 mil) do:
1. France does 500 000 jabs per day
2. South Korea does 200 000+ jabs per day (pop = 65 mil)
8. Are we behind with original targets? Yes.
1. How many doses has SA done? 7.3 mil
2. How many doses should we have done to be on target? 16.5 mil (7 days wk)
3. How far behind are we? 9.2 mil doses
4. How many doses are left to do (for a largely #Pfizer strategy)? 64.6 mil
9. This slide shows the original vaccination targets for each province + how far behind we are:

E.g., Gauteng
1. Original target = 4.2 mil doses
2. We've done: 1.7 mil doses
3. Shortfall = 2.5 mil doses

Main reason for delay: LACK of doses supplied to SA by drug companies
10. How many doses will we have administered by March if we keep going at our current pace?
- 40 mill (we need to do 54.9 mil if we work with a 15% vaccine hesitancy and a largely Pfizer campaign)
11. How is SA performing with #VaccineRollOutSA compared to other African countries?
We've done more vaccinations than most other African countries (only Morocco has done more than us, acc to @mediahackza's dashboard: bit.ly/3xcM5KK)
12. Weekends, public holidays and national events (e.g elections) may affect when SA reaches its #VaccineRollOutSA targets. We need to perform consistently for the entire vaccination period to reach our targets.

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More from @miamalan

Jul 24
🧵1. BREAKING: The peer-reviewed results of the study of a 6-monthly jab, #lenacapavir, in which not a single of the 2134 women between 16-25 years who received the jab contracted #HIV, were released at #Aids2024.

Find the full study here:

bhekisisa.org/wp-content/upl…
Image
2. Women often find it hard to adhere to daily #oralPrEP. In the Purpose 1 trial, 91.5% of women returned on time for their next #lenacapavir jab at 26 weeks and 92.8% at week 52. Image
3. Only 4 women out of 2134 (0.2%) who received #lenacapavir dropped out of the trial because of injection-site reactions. Image
Read 15 tweets
Jan 17
[Thread] 12 things to know about the the proportion of pregnant women infected with #HIV from SA’s latest antenatal HIV survey. The survey is conducted by the @nicd_sa.

(Analysis of our 95-95-95 goals in my next thread later in Jan).

1/12 Image
2. What is the antenatal #HIV survey?

1. It measures the % of HIV+ pregnant women between the ages of 15 + 49.
2. Only women using state pregnancy clinics take part.
3. The survey has been conducted each year between 1990-2015, then in 2017, 2019 +2022. Image
3. How many pregnant women between 15-49’s blood was tested for #HIV? 37 828 out of 40 542 collected samples.
- 37 7171 = Black African women
- 37 541 didn’t live with the dad of their child
- 35,635 of dads were 5 years+ older than moms (this makes them more likely to get HIV) Image
Read 12 tweets
Jan 10, 2023
JUST IN [Thread]:
1.@healthza's Lesley Broomberg:
An extra #COVID19 booster jab for people of 18+ in SA will become available towards the end of JANUARY
- People of 50+ qualify for a 5th dose
- People of 18+ qualify for a 4th dose
2. Lesley Broomberg: Can you mix and match with additional boosters? Yes. You can choose whether you want a #JnJ or #Pfizer booster.
3. Lesley Broomberg:
Will teens of 12-17 qualify for boosters? Not at this stage. Why not? The #VMAC = not recommended booster doses for 12-17, based on an understanding that the protection provided by 2 #Pfizer doses = adequate, as 12-17 = @ low risk of severe #COVID19 illness
Read 5 tweets
Jan 10, 2023
[Thread] #JoePhaahla:
- Genomic surveillance Network reported the detection of the new subvariant XBB.1.5 in SA of a sample of a patient tested on 22 Dec
- Details of the patient = not known, it was a random sample taken for testing
- XBB.1.5 = also common in US
2. XBB.1.5 = common in US
#JoePhaahla:
- 97%+ of #COVID19 cases worldwide = still #Omicron
- XBB.1.5 cases = no major change in hospitalisations or deaths
- Immunity of SAs (vax and natural immunity) = still strong, so that is why we haven't seen much change in terms of hospital admissions/deaths
Read 5 tweets
Dec 13, 2022
🧵1. SA's @aspenpharma will be making 4 jabs (fill + finish) — pneumococcal, rotavirus, meningococcal, hexavalent — from 2023.

How will they finance this?
With a $30 million grant from @CEPIvaccines + @gatesfoundation.

Which APIs will Aspen use?
India's Serum Institute's
2. Why is it NB that an African company makes these jabs?

#Africa imports almost all its jabs. #COVID19 showed us this results in Africa being last in line to get vaccines during pandemics. The grant to Aspen is 1 of the 1st steps to change that.
3. What's the goal?

By 2040, the African Union wants #Africa to make 60% of the jabs the continent uses.

Why?
So that Africa is better equipped 2 respond 2 outbreaks (by developing the ability to make jabs + have technology in place to also make new jabs during pandemics).
Read 6 tweets
Dec 2, 2022
🧵1. BREAKING: @SAHPRA1 has confirmed the registration of the #HIV prevention jab, #CABLA in South Africa. On Thursday, #ViiVHealthcare issued their statement. ImageImage
2. Who can use the jab? @SAHPRA1 didn't specify restrictions for use in their statement, only that it is "a highly effective option for people at substantial risk of #HIV infection." Image
3. How does the jab work? It uses an #ARV called cabotegravir that prevents #HIV from replicating and entering someone’s cells. It’s taken every two months. Read my latest story for more. bit.ly/3ER7ejq
Read 5 tweets

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