10 days ago it was conceivable that NSW could control delta and reach low covid (by int'l standards) well before 80% vax, safely open and reduce covid simultaneously.

Now appears that NSW will barely control covid, at high caseloads (~500/Mpop/day) when reaching 80% vax.
1/ Image
Lines on the graph are extrapolations from 9, 14, and 20 August. In 11 days the extrapolated date of effective* 80% vax of 16+ has moved forward 15 days, and the date of achieving R=1 through vax has moved backwards by 22 days. Separation has gone from 6 weeks to 4 days.
2/
This is a result of the higher observed R, which seems robust.

Likely scenario: NSW will achieve 80% vax of 16+ in October after 3.5 months lockdown, with cases in several 1,000s/day. Pressure to remove lockdown will be intense.
3/
I don't meant to paint this as a doom scenario. NSW population will be highly vaxxed, IFR will be low. Lockdown will have saved lives by buying time for vax.

But, comparisons to UK, Israel which seemed hyperbolic 11 days ago are realistic now. Need to adjust expectations.
4/
11 days ago it seemed hyperbolic to consider an NSW open to international travel while other states kept borders closed to NSW. Now it seems plausible - NSW will be a hotspot even by world standards, and other states lagging in vax.
5/
*effective 80% vax of 16+ means 160 doses per 100 16+ pop.

I assume very simple linear extrapolation of vax, each dose 40% effective against transmission immediately. Ignore reduction in S due to infection. More complex model from @Chrisbilbo comes to same conclusions.
6/6

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More from @MichaelSFuhrer

15 Sep
The UK is often held up as a cautionary tale regarding covid and re-opening.

Let's have a look at what happened in the UK and see if there are parallels to what is happening in Australia.

Thread.
1/🧵 Image
At the beginning of 2021 the UK was fighting a crushing wave of alpha with months of lockdown. As that wave receded, the UK began to release restrictions.

2/🧵
Restrictions were released at a very early stage of the vaccination program:

The UK "picnic day" and end of local-area restrictions to movement occurred on 29 March at 5.6% of total population vaxxed.

Outdoor dining/pubs opened 12 April at 11.5% vax.

3/ 🧵
Read 12 tweets
13 Sep
Some first impressions from the OzSAGE model (ozsage.org/icu-modelling/):

1)Not enough info is given to understand how the model works. They don’t explain how R_eff is calculated, for example, from the restriction settings.

@RichardfromSyd1 @OrinCordus @RageSheen @Globalbiosec
2)They don’t explain their assumptions about ongoing vaccination beyond 80%. This is key to understanding the model and it’s left unstated.
3)They say they adapt a peer-reviewed model, but that model was not used to model time-varying restrictions, and in fact did not include masks or lockdowns at all.
Read 12 tweets
1 Sep
Here is a long/technical thread on my attempt to reverse-engineer the assumptions from the Doherty Institute report to the National Cabinet (linked) regarding delta severity, PHSM effectiveness, and vaccine effectiveness to match observations.
1/🧵
doherty.edu.au/uploads/conten…
Here are the figures from the Doherty Institute report. Note that there are a couple versions of these figures in the report; these assume the “all adults” strategy for vaccination.
2/🧵
The figures attempt to show graphically the effect of various interventions on the transmission potential (TP). TP is in essence R_eff, but calculated on the population level, as I understand it. When TP>1, cases grow, and TP<1, cases decline.
3/🧵
Read 34 tweets
28 Aug
This blog post has received a lot of attention.

A thread.
🧵
In short, the blog post takes public misconceptions about the technical report from Doherty, makes a cursory read of the report, repeats misconceptions, accuses Doherty of intentional scientific misconduct to lead Australia to disaster.

Crackpot stuff.
2/🧵
Not really worth taking apart. But it’s been retweeted by a number of figures who should really know better. So let’s take a look.

Doherty Institute report is here if you want to read along.

3/🧵
doherty.edu.au/uploads/conten…
Read 24 tweets
23 Aug
It is mind-boggling how fast one’s worldview needs to adapt to changing reality during this pandemic.

Taking stock of some new realities:
🧵
1) Delta is tougher than we thought. It is now safe to say that, even at current vax, delta is marginal to escape optimal TTI + lockdown. Some outbreaks fizzle out. But when they don’t, short/sharp lockdowns have become long at best, uncontrolled outbreaks at worst...
...This is ultimately inevitable, and your risk analysis for vax should account for the fact that everywhere is either in outbreak now or only months/weeks from outbreak. Get whatever vax is available to you, as soon as possible, and encourage everyone you know to do the same.
Read 11 tweets

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