The waning of Pfizer and Moderna vaccine protection vs *symptomatic infections* over time in all age groups, slide presented at ACIP @CDCgov meeting by Sara Oliver MD cdc.gov/vaccines/acip/…
(this was the primary endpoint for the pivotal trials to approve these vaccines)
(this was the primary endpoint for the pivotal trials to approve these vaccines)
Red=Delta (Green=pre-Delta)
It's still early into the period of waning, w/ frequency of exposures increasing over time.
Recall the UK (and other countries) decision to provide 3rd shots irrespective of vaccine to all age 50+ is at odds with FDA/CDC (Pfizer only, age 65+)
It's still early into the period of waning, w/ frequency of exposures increasing over time.
Recall the UK (and other countries) decision to provide 3rd shots irrespective of vaccine to all age 50+ is at odds with FDA/CDC (Pfizer only, age 65+)
Meanwhile we have left the people who got a J&J vaccine stranded with comparatively very low antibody levels 2-6 weeks after dosing, while we've learned such levels are tied to protection
cdc.gov/mmwr/volumes/7…
I think that's now ill-considered.
cdc.gov/mmwr/volumes/7…
I think that's now ill-considered.
It's as if the denialists of waning vs symptomatic infections think this issue will just go away over time, despite this endpoint being an accepted surrogate for hospitalizations. Meanwhile this is putting those not covered by current criteria, but at risk, for #LongCovid, too.
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