It's #WorldMentalHealthDay. This thread 🧵 is about #depression and #nicotine. A higher % of people w/depression smoke than people w/o depression. Depression is serious. Seek help if you're silently suffering alone. This isn't easily "fixed" by a lifestyle change! #MIAW21
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#WorldMentalHealthDay
E-cigarette use was not associated with an escalation in depression symptoms.
E-cigarette use was not related to the development of depression symptoms over time.
sciencedirect.com/science/articl…
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E-cigarette use was not associated with an escalation in depression symptoms.
E-cigarette use was not related to the development of depression symptoms over time.
sciencedirect.com/science/articl…
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#WorldMentalHealthDay
"It is postulated that smokers are protected from the consequences of these changes, while they continue to smoke, by the antidepressant properties of nicotine."
sciencedirect.com/science/articl…
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"It is postulated that smokers are protected from the consequences of these changes, while they continue to smoke, by the antidepressant properties of nicotine."
sciencedirect.com/science/articl…
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#WorldMentalHealthDay
Nicotine improves cognitive performance in clinical and preclinical studies.
Nicotine may also benefit depressive symptoms and depressive behavior.
sciencedirect.com/science/articl…
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Nicotine improves cognitive performance in clinical and preclinical studies.
Nicotine may also benefit depressive symptoms and depressive behavior.
sciencedirect.com/science/articl…
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#WorldMentalHealthDay
Cognitive and mood benefits may be mediated by nicotinic effect on neural networks.
Nicotine’s effects on networks may reverse network changes seen in depression.
sciencedirect.com/science/articl…
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Cognitive and mood benefits may be mediated by nicotinic effect on neural networks.
Nicotine’s effects on networks may reverse network changes seen in depression.
sciencedirect.com/science/articl…
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#WorldMentalHealthDay
Improvement to mood and cognition may particularly benefit older depressed adults.
...studies support that nicotine and other nAChR agonists can improve depressive behavior, mood, and cognitive performance.
sciencedirect.com/science/articl…
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Improvement to mood and cognition may particularly benefit older depressed adults.
...studies support that nicotine and other nAChR agonists can improve depressive behavior, mood, and cognitive performance.
sciencedirect.com/science/articl…
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#WorldMentalHealthDay
Through modulation of intrinsic functional networks, nAChR agonists may reduce depressive symptoms, enhance emotional regulation ability, and improve cognitive deficits common in LLD.
sciencedirect.com/science/articl…
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Through modulation of intrinsic functional networks, nAChR agonists may reduce depressive symptoms, enhance emotional regulation ability, and improve cognitive deficits common in LLD.
sciencedirect.com/science/articl…
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#WorldMentalHealthDay
In MDD, acute nicotine administration normalized both pathways to the level of healthy controls... These results indicate that nicotine normalizes dysfunctional cortico-striatal communication in unmedicated non-smokers with MDD.
pubmed.ncbi.nlm.nih.gov/29795403
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In MDD, acute nicotine administration normalized both pathways to the level of healthy controls... These results indicate that nicotine normalizes dysfunctional cortico-striatal communication in unmedicated non-smokers with MDD.
pubmed.ncbi.nlm.nih.gov/29795403
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#WorldMentalHealthDay
There was a significant decrease in MADRS (Montgomery-Asberg Depression Rating scale) over the study, with improvement seen as early as three weeks.
ncbi.nlm.nih.gov/pmc/articles/P…
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There was a significant decrease in MADRS (Montgomery-Asberg Depression Rating scale) over the study, with improvement seen as early as three weeks.
ncbi.nlm.nih.gov/pmc/articles/P…
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#WorldMentalHealthDay
...did observe improvement in subjective cognitive performance and signals of potential drug effects on secondary cognitive measures of working memory, episodic memory, and self-referential emotional processing.
ncbi.nlm.nih.gov/pmc/articles/P…
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...did observe improvement in subjective cognitive performance and signals of potential drug effects on secondary cognitive measures of working memory, episodic memory, and self-referential emotional processing.
ncbi.nlm.nih.gov/pmc/articles/P…
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#WorldMentalHealthDay
These findings suggest a role for nicotinic receptor systems in the pathophysiology of depression and that nicotinic compounds should be evaluated for treating depression symptoms.
pubmed.ncbi.nlm.nih.gov/16977477/
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These findings suggest a role for nicotinic receptor systems in the pathophysiology of depression and that nicotinic compounds should be evaluated for treating depression symptoms.
pubmed.ncbi.nlm.nih.gov/16977477/
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#WorldMentalHealthDay
Acute administration of nicotine patches produced rapid eye movement sleep (REM) increases in non-smoking major depressed patients as well as clinical improvement in mood.
pubmed.ncbi.nlm.nih.gov/11995405
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Acute administration of nicotine patches produced rapid eye movement sleep (REM) increases in non-smoking major depressed patients as well as clinical improvement in mood.
pubmed.ncbi.nlm.nih.gov/11995405
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#WorldMentalHealthDay
Antidepressant effect was also observed after four continuous days of nicotine administration.
pubmed.ncbi.nlm.nih.gov/11995405
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Antidepressant effect was also observed after four continuous days of nicotine administration.
pubmed.ncbi.nlm.nih.gov/11995405
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#WorldMentalHealthDay
Individuals with a history of depression have a much harder time giving up smoking. It has been postulated that smoking may reflect an attempt at self-medication with nicotine by these individuals.
link.springer.com/article/10.100…
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Individuals with a history of depression have a much harder time giving up smoking. It has been postulated that smoking may reflect an attempt at self-medication with nicotine by these individuals.
link.springer.com/article/10.100…
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#WorldMentalHealthDay
The data strongly implicate the involvement of central nicotinic receptors in the depressive characteristics of the FSL rats, and suggest that nicotinic agonists may have therapeutic benefits in depressive disorders.
link.springer.com/article/10.100…
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The data strongly implicate the involvement of central nicotinic receptors in the depressive characteristics of the FSL rats, and suggest that nicotinic agonists may have therapeutic benefits in depressive disorders.
link.springer.com/article/10.100…
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#WorldMentalHealthDay
These findings suggest that nicotine receptor activation may be important in major depression and shows for the first time that nicotine patches may be useful in the treatment of depression.
pubmed.ncbi.nlm.nih.gov/9592048
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These findings suggest that nicotine receptor activation may be important in major depression and shows for the first time that nicotine patches may be useful in the treatment of depression.
pubmed.ncbi.nlm.nih.gov/9592048
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#WorldMentalHealthDay
A high frequency of cigarette smoking has been reported among individuals with major depression.
Results of the visual analog scale and HAM-D showed a significant improvement in depression after the 2nd day of nicotine patches.
pubmed.ncbi.nlm.nih.gov/9746444
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A high frequency of cigarette smoking has been reported among individuals with major depression.
Results of the visual analog scale and HAM-D showed a significant improvement in depression after the 2nd day of nicotine patches.
pubmed.ncbi.nlm.nih.gov/9746444
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#WorldMentalHealthDay
Depressed smokers using the nic gum reported fewer depressive symptoms 1wk after cessation than at the baseline assessment. Depressed smokers using placebo gum and nondepressed smokers reported no change in depressive symptoms
psycnet.apa.org/record/1996-00…
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Depressed smokers using the nic gum reported fewer depressive symptoms 1wk after cessation than at the baseline assessment. Depressed smokers using placebo gum and nondepressed smokers reported no change in depressive symptoms
psycnet.apa.org/record/1996-00…
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#WorldMentalHealthDay
The main finding of the present study was that nicotine patches induced an increase in REM sleep time in depressed patients without any other changes in sleep variables. They also showed a short term improvement of mood.
pubmed.ncbi.nlm.nih.gov/8619011/
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The main finding of the present study was that nicotine patches induced an increase in REM sleep time in depressed patients without any other changes in sleep variables. They also showed a short term improvement of mood.
pubmed.ncbi.nlm.nih.gov/8619011/
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#WorldMentalHealthDay
There is, then, no evidence in these data that the occurrence of MDD in persons with a prior history of nicotine dependence might have been caused directly by recent persistent smoking.
jamanetwork.com/journals/jamap…
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There is, then, no evidence in these data that the occurrence of MDD in persons with a prior history of nicotine dependence might have been caused directly by recent persistent smoking.
jamanetwork.com/journals/jamap…
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#WorldMentalHealthDay
When chronically taken, nicotine may result in... mood normalization...
pubmed.ncbi.nlm.nih.gov/1859921
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When chronically taken, nicotine may result in... mood normalization...
pubmed.ncbi.nlm.nih.gov/1859921
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