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Chise 🧬🧫🦠💉🔜 BWS GOH

@sailorrooscout

15 Oct

Just HOW effective are the COVID-19 vaccines at protecting you from severe illness and hospitalization even in the face of Delta?

BEFORE Delta variant increase: 95% effective

DURING Delta variant increase: 92% effective

Answer: VERY EFFECTIVE

Let’s discuss. 🧵

Real-world data out of King County, WA (which includes Seattle) confirms vaccinated individuals are significantly better protected from illness, hospitalization, AND death due to COVID-19 compared to unvaccinated individuals, even as the Delta variant surges through the state.

Over the PAST 30 days, unvaccinated individuals were:
•9X more likely to test positive for COVID-19 (65% of cases)
•48X more likely to be hospitalized for COVID-19 (77% of hospitalizations)
•69X more likely to die of COVID-19 related illness (74% of deaths)

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Chise 🧬🧫🦠💉🔜 BWS GOH

@sailorrooscout

14 Oct

This is what we have been waiting for! A study out of NIH shows heterologous COVID-19 booster vaccinations of Moderna, Pfizer, and Johnson & Johnson induce strong humoral immune responses (up to a 76X increase in nAbs) with acceptable reactogenicity profiles. Let’s discuss. 🧵

This particular study involved 458 participants. They were divided into nine groups with roughly around 50 participants in each group. Those who initially got Moderna’s vaccine got either another dose of Moderna, a dose of Pfizer, or a dose of Johnson & Johnson as a booster four

to six months after their primary immunization. Those who got Pfizer’s vaccine got either another dose of Pfizer or a dose of Moderna or a J&J booster. And those who received one dose of J&J initially either got another dose of J&J or a Moderna or Pfizer booster dose.

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Chise 🧬🧫🦠💉🔜 BWS GOH

@sailorrooscout

13 Oct

After 548 days of restrictions to limit the spread of COVID-19, Denmark's high vaccination rate has enabled the country to become one of the first European Union nations to lift ALL domestic health measures. More than 85% of the eligible Danish population is fully vaccinated. 🧵

The return to normality has been gradual, but as of October 8th, the digital pass- proof of having been vaccinated- is no longer required when entering nightclubs, making it the LAST virus safeguard to fall. The Danish government NO LONGER considers COVID-19

a socially critical disease. “Denmark is lifting the restrictions because the vaccine rollout has been very successful," said Jens Lundgren, Professor of Viral Diseases, Copenhagen University Hospital. “As a consequence, we have the pandemic under control in this country and can

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Chise 🧬🧫🦠💉🔜 BWS GOH

@sailorrooscout

12 Oct

An analysis of ~250,000 in Canada found two doses of any of the three COVID-19 vaccines (Moderna, Pfizer, AstraZeneca) led to strong protection from infection, hospitalization, AND death -even against Delta- REGARDLESS of the vaccination combination and showed NO signs of waning.

Preliminary data from researchers at the British Columbia Centre for Disease Control (BCCDC) and the Quebec National Institute of Public Health (INSPQ) shows the decision to vaccinate more Canadians sooner by delaying second shots by up to four months saved lives.

The researchers excluded long-term care residents from the data, who are generally at increased risk of hospitalization and death from COVID-19, in order to get a better sense of vaccine effectiveness in the general population. Needless to say the results were exceptional.

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Chise 🧬🧫🦠💉🔜 BWS GOH

@sailorrooscout

10 Oct

Yes, the vaccines ARE effective against the Delta variant. Yes, you will want both doses for maximum protection. Yes, they’re effective against preventing symptomatic infection, severe disease, AND hospitalization. Several studies have proven this now. Stop the misinformation.

Also, yes, this does include Johnson & Johnson. Why are variants unlikely to FULLY evade vaccine-induced immunity?
•Vaccines are polyclonal (Abs)
•CD8+ T-cells covering 52 epitopes across the spike protein
•CD4+ T-cells covering 23 epitopes across the spike protein

If you have time this week, I recommend:
•sciencedirect.com/science/articl…
•theatlantic.com/ideas/archive/…
•theatlantic.com/science/archiv…
•theatlantic.com/science/archiv…
•npr.org/sections/goats…
•theatlantic.com/science/archiv…
•theatlantic.com/science/archiv…
•theatlantic.com/science/archiv…
•medium.com/geekculture/no…

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Chise 🧬🧫🦠💉🔜 BWS GOH

@sailorrooscout

8 Oct

“Breakthrough” infections DO NOT mean vaccines don’t work. Remember, they are preventives, NOT cures. One can still contract COVID once vaccinated. As long as that vaccine is preventing you from facing severe disease and worse, it IS working and doing what it was designed to do.

Regarding the concerns about waning immunity. Please remember, this is likely referring to infection. NOT effectiveness against symptomatic infection, NOT effectiveness against severe illness. While neutralizing antibodies decrease over time (as they ARE supposed to) protective

immunity provided by memory B-cells and T-cells is STILL present. Remember: Immunological memory consists of antibodies, memory B-cells, memory CD8+ T-cells, and memory CD4+ T-cells. These responses give us enduring protection even against newly emerging SARS-CoV-2 variants.

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Chise 🧬🧫🦠💉🔜 BWS GOH

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