Thread by @sailorrooscout

Yes, the vaccines ARE effective against the Delta variant. Yes, you will want both doses for maximum protection. Yes, they’re effective against preventing symptomatic infection, severe disease, AND hospitalization. Several studies have proven this now. Stop the misinformation.🧵

Also, yes, this does include Johnson & Johnson. Why are variants unlikely to FULLY evade vaccine-induced immunity?
•Vaccines are polyclonal (Abs)
•CD8+ T-cells covering 52 epitopes across the spike protein
•CD4+ T-cells covering 23 epitopes across the spike protein

Real-world data out of Ontario, Canada regarding vaccine effectiveness (reduction associated with full vaccination) shows:

•Against Infection: 85.3%
•Against Hospitalization: 95.1%
•Against ICU Admission: 96.3%

Delta is currently the most prevalent variant in Ontario.

Data as of October 20th below. The COVID-19 vaccines are very effective at protecting you from severe illness and hospitalization even in the face of Delta. You can find this information and more here: covid19-sciencetable.ca/ontario-dashbo…

COVID-19 data between July and October out of the Peel region of Ontario shows out of 5,593 cases:
•80% of COVID-19 cases, 85% of hospitalizations, and 62% of deaths were NOT fully vaccinated
•16 cases were admitted to ICU, ALL were unvaccinated and 63% were less than 50

•11 cases under the age of 20 were hospitalized, ALL were unvaccinated
•16% of hospitalizations and deaths were among fully vaccinated individuals. Of these fully vaccinated cases, 83% were age 60+ years
You can find all this information and more here: peelregion.ca/health-profess…

The CDC is NOW posting national data on vaccination status for hospitalization and death due to COVID-19 and it IS stratified by age. In August unvaccinated individuals were:
•6X more likely to test positive for COVID-19
•11X more likely to die of COVID-19 related illness

You can find this information here: covid.cdc.gov/covid-data-tra… (you will need to switch views to see cases vs. deaths). Even in the face of Delta, these vaccines are indeed effective against preventing symptomatic infection, severe disease, hospitalization AND death due to COVID-19.

Published in NEJM. Peer-reviewed. Sounds methodology. Delta outbreak in a California detention center (close quartera). Moderna’s vaccine was found to be 84% effective against symptomatic infection. NO hospitalizations among fully vaccinated individuals. nejm.org/doi/full/10.10…

“Results indicate that Moderna’s vaccine was quite effective against SARS-CoV-2 infection during a Delta variant–driven outbreak in this high-risk, congregate setting. Although the effectiveness against infection was substantially lower than that estimated in studies conducted

before the emergence of the Delta variant, protection against symptomatic illness remained robust-an outcome consistent with other recent reports. Full vaccination also conferred additional substantial protection against infection in men with previous confirmed infections.”

Another study published in NEJM. Peer-reviewed. Large sample size (5.4 MILLION). Sound methodology. Pfizer’s and AstraZeneca’s vaccines are highly effective against the Delta variant. Pfizer was found to be 90% effective against COVID-19 related death caused by infection

with Delta, and AstraZeneca’s vaccine was found to be 91% effective against against COVID-19 related death caused by infection with Delta. No deaths had been recorded in those who have been double vaccinated with Moderna’s vaccine in Scotland, according to the data.

You can read more here: nejm.org/doi/full/10.10… and here: thejournal.ie/vaccines-effec…. Conclusion? Even in the face of Delta, these vaccines are indeed effective against preventing symptomatic infection, severe disease, hospitalization AND death due to COVID-19.