Thread by @herbaronowMD

1/8 It was not unexpected that pts w/ #STEMI would fare worse w/ than w/o #COVID19

https://twitter.com/JAMA_current/status/1454115833580507140

2/8 However, our study was unique in design compared w/ prior studies, allowing for more accurate estimates of mortality risk: 1) larger, more representative cohort; 2) more contemporary control groups

3/8 We characterized mortality risk separately for pts with pre-hospital and in-hospital #STEMI

4/8 We included 2 control groups: 1) Pts w/o #COVID19 admitted w/ #STEMI during the pandemic; 2: pts w/o #COVID19 admitted w/ #STEMI before the pandemic

5/8 Key finding #1: Pts w/ #COVID19 who were admitted with #STEMI or developed #STEMI while hospitalized fared much worse than their COVID-negative counterparts wrt mortality (15% vs 11% pre-hospital; 78% vs 46% in-hospital)

6/8 Key finding #2: Pts w/o #COVID19 who were hospitalized w/ #STEMI during the pandemic fared just as well as similar pts hospitalized before the pandemic, suggesting that pandemic-related factors were not to blame for increased mortality with #COVID19 in pts w/ #STEMI

7/8 Take home message #1: Pts at risk for #STEMI should do everything possible to address modifiable #cardiovascular risk factors (#diet, #exercise, #smoking-cessation, #HTN, #HLD, #DM)

8/8 Take home message #2: Everyone must do their part to mitigate risk of developing/spreading #COVID19 (#masks, #SocialDistancing, #Covidvaccination); true for those at risk for #STEMI and true for those who might spread the disease to those at risk

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