Discover and read the best of Twitter Threads about #exercise

Most recents (24)

This one found that the consumption of skimmed milk after exercise may reduce subsequent energy intake, such that total energy intake is not different from a low-energy placebo beverage and reduced relative to a sucrose beverage.
"The main finding was that ad-libitum energy intake 60 min after beverage ingestion was reduced following skimmed milk compared to a sucrose beverage and tended to be reduced for skimmed milk compared to the placebo beverage...
"...This meant that total energy intake (ad-libitum energy intake plus the energy provided in the post-exercise beverage) was lower following skimmed milk and placebo compared to after ingestion of the sucrose beverage...
Read 6 tweets
In this one, both 3mg/kg and 6mg/kg doses of caffeine ingestion increased plasma catecholamine concentration and improved the average peak power output during a repeated sprint test in trained female team-sport players.
- Both doses of coffee ingestion improved the average peak power output attained by participants during the repeated sprint test compared to placebo, with no differences between doses.
- Peak and mean power output and the fatigue index did not improve during the individual sprints.
Read 4 tweets
In this one in mice, resistance exercise was found to counteract the effects of an obesogenic diet on body composition, while also being associated with improved glucose tolerance, even after exercise cessation. Image
- The study wanted to investigate the preventive effects of resistance exercise on body weight, gonadal fat mass, and glucose tolerance and determine whether the beneficial effects of exercise are associated with skeletal muscle strength and endurance in mice.
- Skeletal muscle strength (as measured by grip strength) and skeletal muscle endurance (as assessed by hanging time) were increased, even after exposure to an obesogenic diet for 1 week (~280 human days) after exercise discontinuation. Image
Read 10 tweets
This one found that a higher-intensity aerobic exercise is more likely to elicit greater increases in circulating exercines that are known for their neuroprotective effects.
- Findings showed that Cathepsin B was enriched in the circulation in an intensity dependent manner during aerobic exercise.
- Interestingly, skeletal muscle tissue was found expresses both message and protein of Cathepsin B (CTSB) and brain derived neurotrophic factor (BDNF), with the latter being highly expressed in glycolytic skeletal muscle fibers.
Read 4 tweets
This one found bodily pain to increase in severity with ageing, with increasing TV time at any given time point to also increase the risk of severity of bodily pain in Australian adults with and without type 2 diabetes.
- Bodily pain severity increased with age, and increasing TV time at a given time point was associated with increased severity of the bodily pain which persisted after adjustment for relevant confounders, including leisure-time physical activity and waist circumference.
- The relationships of increasing TV time with bodily pain severity at a given time point on the bodily pain trajectories were more pronounced in those with type 2 diabetes than in those without.
Read 5 tweets
In this study in children aged 10-12 years, only the energy expenditure spent through vigorous intensity physical activity was found to be inversely related to measures of fat mass. Image
- For a given energy expenditure dose measured with objective accelerometer data, the energy expenditure spent through vigorous intensity physical activity was inversely related to fat mass and abdominal fat mass index.
- Energy expenditure spent through moderate intensity physical activity was not related to fat mass and abdominal fat mass index when accounting for the energy expenditure spent through vigorous intensity physical activity.
Read 7 tweets
In this one, the addition of protein in a resistance training program was more effective than the program alone in increasing skeletal muscle mass and strength in older adults, and was also associated with less declines in skeletal muscle mass and strength after cessation. Image
- The PRO supplement beverage contained 160 kcal of energy, 11.0 g of protein, 2.2 g of fat, 24.0 g of carbohydrate, and 2,300 mg of leucine per serving.
Participants in the RT+PRO group ingested the protein supplement within 5 min after completion of the RT program.
Read 7 tweets
This narrative review explores the mechanisms of action and efficacy of caffeine and the potential for combinations of caffeine and other dietary compounds to exert psychological effects in excess of those expected following caffeine alone.
Key Points:
- Caffeine, when taken alone, is associated with reasonably consistent ergogenic and psychological benefits. However, its effects on mental performance are limited, and do not encompass benefits to several sport-relevant cognitive domains.
Read 8 tweets
1. You can get all the #exercise you need in just 8 minutes a day if you work out a bit harder, according to a new study.

Just 54 minutes of vigorous exercise per week can lower the risk of early #death from any cause by 36%, and chances of getting #heart disease by 35%. Image
2. Current guidelines recommend 150–300 min of moderate-to-vigorous physical activity, 75–150 min of vigorous physical activity, or a combination of both/week. However, 50-75% of population can not fulfil this due to various reasons.
8 min/day should be manageable for majority.
Take home message
Short bouts of vigorous exercises (8-10 min/day) may be a good option for busy people.
#fitness #running #MedTwitter
Reference
doi.org/10.1093/eurhea…
Read 3 tweets
Regular #exercise effectively reduces #headache days in patients with #migraine

1. Migraine is a disabling disease that causes repeated episodes of headaches.
Exercise is very effective, however, it is uncommonly prescribed in migraine.
#MedTwitter #neurotwitter
2. In a recent research, strength/resistance training reduced monthly migraine days (MMD) by 3.5 days, followed by high-intensity aerobic exercise (3.1 days) and moderate intensity aerobic exercise (2.2 days).
3. All exercise modalities showed higher efficacy compared to placebo.
The reason for strength/resistance training to rank top could be because of targeted muscular strengthening and reconditioning, particularly involving major muscles in the neck, shoulders and upper limbs.
Read 12 tweets
Can #drinking excess amount of #water lead to death?

1. Water is life-saving and is essential for survival. However, ingestion of excess amounts of water, especially over a short period of time can lead to serious health hazards, including #death.
#MedTwitter #internalmedicine
2. How much water is needed on daily basis?

The normal daily requirement of water is 2.5 to 3 liters.
The requirement may be higher in summer months. Requirement also increases during #exercise (due to sweating), during fever, diarrhea or vomiting.
3. Why do some people drink excess amounts of water?

There is a misconception that drinking more water is good for #health.
Some people can drink more water due to #psychiatric illnesses.
#athletes can overestimate fluid loss and drink an excess amount of water.
Read 9 tweets
This one found that individuals without obesity who follow a healthy diet and are physically active are likely to have the lowest risk of all-cause and cardiovascular mortality, but adhering to either one of the aforementioned healthy behaviors may still confer risk reduction.
- A 21, 16, and 9 percentage risk reduction in all-cause mortality in individuals who engaged in both healthy behaviors, only physical activity, and only a healthy diet was observed, respectively.
- Individuals who both followed a healthy diet, and were active and females who were active only showed a 26 and 17% decrease in cardiovascular disease mortality respectively, whereas no statistically significant associations were observed for those following a healthy diet only.
Read 4 tweets
This one suggests that age acceleration is associated with lower strength and/or loss of strength over time in US adults aged 51 years and older, followed over an 8-10 year period.
- "A growth in research evidence documents that epigenetic phenomena, such as DNA methylation (DNAm), are highly implicated in the development of disease and rate of biological ageing...

Ref:
doi.org/10.1186/s13059…
"...Given that methylation profiles are thought to be modifiable by lifestyle and other environmental factors, it has been proposed that DNAm age is a robust biological ageing clock providing a superior estimate of true biological age over chronological age...
Read 13 tweets
Here, leisure-time sedentary behavior was associated with the risk of dementia incidence and mortality, but replacing it with a short duration of physical activity was associated with a decreased risk of dementia, with the effect being stronger in APOE ε4 carriers. Image
- The apolipoprotein E (APOE) gene is the strongest genetic factor modulating risk for Alzheimer's Disease and dementia.
This gene has three common alleles, the protective allele APOE ε2, the neutral allele APOE ε3, and the risk allele APOE ε4.
Read 11 tweets
#diabetes and #Neurology
1. Peripheral #neuropathy can be the first manifestation of diabetes. 50-70% of diabetics suffer from neuropathy. Pain and burning sensation of feet are common symptoms. Numbness of feet can predispose to ulcer formation.
#WorldDiabetesDay #Medtwitter
2. Diabetes is a common risk factor of #stroke, seen in 30% of stroke cases. Diabetes leads to poorer outcome in stroke patients- longer length of hospital stay, higher risk of complications, higher risk of death due to stroke and greater disability in stroke survivors.
3. Diabetes is associated with higher risk of dementia including Alzheimer's disease. The risk of mild cognitive impairment (MCI) and conversion of MCI to dementia is higher in diabetics. Longer duration of diabetes and uncontrolled diabetes further increase the risk of dementia.
Read 8 tweets
This study in Finnish twins finds that an unhealthy lifestyle during pubertal years (obesity, smoking, binge drinking, low levels of physical activity) is associated with accelerated biological aging in young adulthood.
- Both the class with the overall unhealthiest lifestyle and that with a high BMI were biologically 1.7–3.3 years older than the classes with healthier lifestyle patterns when DNAm GrimAge was used...
... and had 2–5 weeks/calendar year faster pace of biological aging when using DunedinPoAm.
Read 6 tweets
Using Mendelian randomization analysis and conventional analysis, this one finds fat mass to be causally and linearly associated with all-cause mortality, while showing that the obesity paradox found in observational analyses can be explained by high-risk lifestyle choices.
- The phenomenon where a higher BMI correlates with lower mortality risk has been called the obesity paradox.
- In order to investigate the association between fat mass and mortality and mortality not only among the whole population, but to be able to stratify in subgroups as well, the authors used six well-known lifestyle risk factors to assess high/low risk lifestyles.
Read 12 tweets
This one found Spanish university students with a higher meat consumption to be more likely to have a higher muscle strength index, but with total protein intake and lean mass completely mediating this effect.
- University students with high meat (total, red, processed, and white and fish) consumption were more likely to have a higher muscle strength index than their peers with lower meat consumption.
- When total protein intake and lean mass percent were added to the statistical model, these associations lost statistical significance.
Read 8 tweets
1) The commonest factor that puts people off a healthier lifestyle is the 'all or none' principle.

This is what I have learnt after dealing with lifestyle diseases for over 5 years and having faced certain issues of my own.

I will explain this in my tweet.
2) What is the 'all or none' aka AON principle?

It is the presumption that you have to follow the diet/gym/morning walk schedule EXACTLY as it is.

If you don't complete it, there is no benefit.
3) This AON principle, in my humble opinion, pertains to medication only.

Why?

If you are taking meds for lifestyle diseases (LD) --> you are in the 2ndary prevention phase where you aim to prevent COMPLICATIONS! Image
Read 13 tweets
This one found serum klotho levels, a protein primarily produced by the kidney which is considered to be anti aging and its levels appear to increase with exercise, to be negatively associated with heart failure in middle-aged and older adults.
- Each 2.72 pg/ml increase in Klotho concentration decreased the risk of heart failure by 45% after controlling for potential covariates, and such a negative and significant association was also found in half of the subgroups.
"Our findings indicated that a higher serum Klotho concentration was significantly associated with a lower risk of HF in half of the subgroups...
Read 12 tweets
This umbrella review of meta-analyses found strong evidence to suggest that physically active individuals have a lower risk of developing Alzheimer's Disease and that exercise interventions exert numerous benefits on patients who already have Alzheimer's Disease. Image
- The present umbrella review found that there is strong evidence of a protective effect of regular physical activity against Alzheimer's Disease risk, with active individuals having a~ 30–40% lower risk compared with inactive individuals.
- "Although a dose–response association between physical activity volume and risk of dementia has been previously reported...

Ref:
doi.org/10.1136/bmjope…
Read 12 tweets
Relationship of #distance #run per week to coronary #Heart disease risk factors

1. Guidelines recommend 30 minutes of vigorous #exercise on most days, if not all days. What is the effect if one exceeds these limits? Is it beneficial or harmful?
#running #fitness #marathon
2. Compared with runners who ran less than 16 km (10 miles) per week, long-distance runners (≥80 km/wk) showed:
#2.5 times higher prevalence of HDL>60 (protective against heart disease)
#50% reduction in hypertension
#>50% reduction in need to BP or cholesterol lowering drugs
3. Estimated age-adjusted 10-year coronary heart disease (CHD) risk was 30% lower in runners who averaged more than 64 km/week than in those who averaged less than 16 km/week (42 vs 61 events per 1000 men).
Read 5 tweets
Why do some #doctors do not include advice on #diet and #exercise in their #treatment plan for #patients?
1. It is clear that with modifications in diet & #lifestyle and exercise; we can prevent, control, reduce the severity or cure diseases and improve patient's quality of life.
2. Still we see that patients are given options of medicines and surgery but very little advice about diet and exercise, even though these don't cost much (in comparison to other medical interventions). Patients almost always ask for these advices though.
3. What could be the reasons?
a. There are fewer research papers on role of diet and exercise in disease prevention and treatment. This is not a surprise, as most of the research is pharma-funded, and #Pharmaceuticals have little to gain if diet/exercise prove to be beneficial.
Read 8 tweets
Here, physically inactive primary care patients aged between 19 and 80 years living in Spain, were more likely to have a reduced risk of mortality by increasing their physical activity, even in doses below the recommended levels.
- Physical activity levels in this inactive population of primary care patients translated into risk reductions in mortality.
- These benefits followed a clear dose–response relationship, in which mortality started to fall even with only small increases in physical activity.
Read 5 tweets

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