RIVM preprint 👇
The estimated disease burden of acute COVID-19 in the Netherlands in 2020, in disability-adjusted life-years.
(under peer-review, below are some highlights)
#epitwitter #covid19nl #rivm
assets.researchsquare.com/files/rs-10267…
Study objectives were to quantify the total disease burden of acute COVID-19 in the Netherlands in 2020 using the disability-adjusted life-years (DALY) measure, and to investigate how disease burden varies between age-groups and occupation categories.
Authors estimated:
- total years of life lost (YLL),
- years lived with disability (YLD),
- disability adjusted life years (DALY) due to COVID-19.
One DALY represents the loss of the equivalent of one year of full health.

(It combines years of life lost due to premature mortality, YLLs and years of life lost due to time lived in states of less than full health, or years of healthy life lost due to disability,YLDs.)
Results:
Total burden of acute COVID-19 in 2020 were estimated at 273,000
This means 273K years of full health lost!
43% of the disease burden among those under 30 years, was due to Years of healthy Life lost due to Disability.
43% of disease burden in youth!
The total disease burden due to acute COVID-19 in the Netherlands was overwhelmingly determined by premature mortality.
>99% of years of life lost due to Disability were due to premature deaths.
Let that sink in.
Conclusions:
SARS-CoV-2 infection and associated premature mortality was responsible for a considerable direct health burden in the Netherlands, despite extensive public health measures.
Total DALY were much higher than for other high-burden infectious diseases.
Another thing to bear in mind is that this study only looked at year 2020 and did not measure the effects of longcovid/long term health consequences of covid19 infection.
Factor those in and the already devastating numbers would be higher.

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More from @phenomstruck

29 Apr
thelancet.com/journals/lance…
SARS-CoV-2 elimination, not mitigation, creates best outcomes for health, the economy, and civil liberties.
Public health, economic growth, democratic solidarity, and civil liberties are important factors when evaluating pandemic responses. There is mounting evidence that these objectives do not need to be in conflict in the COVID-19 response.
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15 Oct 20
Scientific consensus on the #COVID19 pandemic: we need to act now.
One look at the authors list, and you'll see thought leaders in their fields; working diligently and with scientific evidence to make a difference.
"Just facts" in here, nothing else.
thelancet.com/lancet/article…
The #herdimmunity approach is a dangerous fallacy unsupported by the scientific evidence
The Barrington Declaration for focussed protection towards herd immunity has no basis in science and evidence. Full stop. It is a misguided self-aggrandising document, similar to the one circulating with patient zero at the White House.
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12 Oct 20
Het had niet zo ver hoeven komen – en het kan zo niet verder.
A point which a lot of us have been hammering (pun intended) in for months now.

nrc.nl/nieuws/2020/10…
We have technical resources, we have scientific expertise, we have diversity in our experiences- @rivm and #OMT should consider using all the help they can.
@C19RedTeam has offered their cross-functional expertise. A pandemic isn't just a medical issue, it is a societal issue.
Rather than rejecting any/all collaboration, @rivm and #OMT (for all their excellence) need to be inclusive, swallow their pride and open up.
All the evidence that they have made their recommendations on, needs to be in public domain.
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23 Sep 20
Have we misjudged the role of children in spreading #COVID19?
COVID19 research in to kid, especially younger ones, is not perfect. It has gaps, it is evolving and we are learning more by the day.
A short summary of evolving role of children 👇
cmaj.ca/content/192/38…
Statement from Ontario’s science advisory table:

- Kids may play a bigger role in the spread of #SARSCoV2 than initially suspected.

- Early suggestions that children are considerably less important drivers of transmission are not confirmed by more recent research.
Children less susceptible?
1. Contact tracing studies reported that children<10 years old are less likely to test positive.

Limitations: Studies underestimate infection rate in children if infected children are more likely to be asymptomatic than infected adults.
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16 Sep 20
@IHME_UW (Institute for Health Metrics and Evaluation) and @UWMedicine (University of Washington’s School of Medicine), no lightweights, have come out with
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Short summary 👇

healthdata.org/news-release/f…
They modelled 3 scenarios:
1. Worse case:
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This leads to 4.0 million total deaths by the end of the year.
Best case:
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27 Aug 20
Huge respect for Aura but some of her responses are contentious. I thank her for the work that she and her team are doing in this ever developing #covid19 pandemic. But one didn't need to understand #coronavirus to implement certain rules.
volkskrant.nl/ts-b73f5cef
Question: Maar anderzijds had u ook best kunnen adviseren: bescherm jezelf nou maar, voor de zekerheid.

Aura: Zeker. Maar dat is met de kennis van nu. Wat we in maart, april dachten te weten over het virus is achterhaald door de snelheid waarmee het zich bleek te verspreiden.
Has any of the field epidemiologists been involved in the decision making, they would have insisted on PPE/masks in healthcare/nursing homes.

Crisis management experts would have insisted it is better safe than sorry.
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