7. Question: "what is a bat transcriptome"
Answer vía @pathogenetics
"That portion of a bat DNA genome that is transcribed into RNA. (The rest is not), so basically the important part of a genome, which means that having these translated bits from a bat's transcriptome...
8. Answer continued
....showing up in the sequence data of the virus genomes, says this viral sequence was propagated in live bat cells, as only live bat cells can transcribe bat DNA into transcribed Bat RNA"
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"The article is, frankly speaking, utter bullshit. It’s a review of available data & the very first referenced work states the opposite of what he claims"
2. Quote from Worobey
“Despite assertions to the contrary (1), it is now clear that live mammals susceptible to coronaviruses, including raccoon dogs (Nyctereutes procyonoides), were sold at Huanan Market & three other live-animal markets in Wuhan before the pandemic (2, 3).”
3. Incorrect Citations
Plainly, reference 1 should assert that no live mammals susceptible to coronaviruses were sold at the live animal markets in Wuhan.
In fact, reference 1 states the exact opposite on Pages 8 and 108 (conclusions)
"the approach. will be targeted to a specific pathogen, but It Is applicable to several different pathogens. For example, an approach may be used to develop therapeutics against 20 different pathogens"
3. Professor Ron Taylor
This project started in May 1996 at the University of Virginia. Taylor and his colleagues developed a heteropolymer that functions on the one end to connect to the CR 1 site of the red blood cells, while the other end is tailored to the specific pathogen.
Let’s take a look at the co-authors of the March 17th Nature letter:
I realised, to my surprise, that I had already encountered 3 of the 5 co-authors & they were not people whose work had impressed me on identifying the origins of diseases
3. Eddie Holmes
"It is therefore possible that he is unconsciously sympathetic to Chinese colleagues, and sensitised to avoiding the causing of embarrassment to his hosts"
New documents back theory that Covid outbreak started in Wuhan lab
The emails uncovered by White Coat Waste Project suggest that viral DNA from “bats and other high-risk species” were sent to Wuhan between 2017 and 2019.
Just stating the obvious that THE FIRST CASE WAS NOT IN DECEMBER exposes the mendicant analysis of that recent piece, which feeds of the scraps of data left by China and then props itself up on odd logical shortcuts.
Useful Point by @baobaoxiaoliao
Dr.Worobey, here are some information you might interest in. In the early stage of the outbreak, China Gov only allows patients with Market contact history to receive tests. Is that a bias that can cause misinterpretation?