"The article is, frankly speaking, utter bullshit. It’s a review of available data & the very first referenced work states the opposite of what he claims"
2. Quote from Worobey
“Despite assertions to the contrary (1), it is now clear that live mammals susceptible to coronaviruses, including raccoon dogs (Nyctereutes procyonoides), were sold at Huanan Market & three other live-animal markets in Wuhan before the pandemic (2, 3).”
3. Incorrect Citations
Plainly, reference 1 should assert that no live mammals susceptible to coronaviruses were sold at the live animal markets in Wuhan.
In fact, reference 1 states the exact opposite on Pages 8 and 108 (conclusions)
This article is not off to a good start…
4. Main Finding
The main "finding" of this paper is that the earliest case confirmed by RT-PCR* actually had a later symptom onset
* Note that the paper lacks the nuance to distinguish between retrospectively diagnosed cases from Nov 2019 & 1st PCR confirmed cases in Dec 2019"
5. The paper says:
"This is corroborated by hospital records and a scientific paper that reports his COVID-19 onset date as 16 December and date of hospitalization as 22 December (13)."
None of the patients it describes have a symptom onset date of 16 Dec, nor a hospitalization date as 22 Dec.
There is one patient with the identifier "Sample WH19002" which has an symptom onset date of 22 Dec, but the hospitalization date in 29 Dec.
7. How did this get published?
There is no relevant data in the supplementary data about the 16-22 Dec patients.
Their first reference says the opposite of what they claim it says.
Their most crucial reference does not say what they claim it says.
How did this get published?
8. Ignoring Phylogenetic Data
The article goes on to ignore all the phylogenetic data in which all the Huanan market cases were lineage B, and that lineage A and lineage B split in November or earlier.
9. Worobey's Map
It goes on to use a similar map to the terrible propaganda map used by Holmes et al:
Similar to the false and misleading statements made in the propaganda by Holmes et al, they claim
“Unfortunately, no live mammal collected at Huanan Market or any other live-animal market in Wuhan has been screened for SARS-CoV-2–related viruses (1)”
12. Reference 1 actually says the opposite:
“A total of 457 animal-related samples from 188 individuals of 18 species were collected and tested between 1st January and 2nd March"
13. Splitting Hairs
It also tries to split hairs & misdirect by focusing on “live mammals” when frozen samples were available
To (falsely) mention a lack of screening of “live mammals collected at Huanan Market”, without mentioning the screening that was done, reeks of bias.
14. Failed!
If an undergrad student submitted a paper with such poor references, (s)he would be failed. Frankly, I find it abhorrent that this paper was published in Science with such blatant errors.
15. Hedging his Bets?
Sadly, it is written by one of the authors of the previous paper:
It seems Michael Worobey is no longer in the academic company of Relman and Bloom, but of Holmes and Rambaut.
(Listed in the Acknowledgements)
16. Fake Research and Propaganda
Someone needs to call attention to the infiltration of “fake news” into our scientific journals, and the utter failure of editorial discretion and peer review to stop it.
17. Conclusión
The very core of science is under attack, and if nothing is done, the public will rightly lose faith in the scientific community.
"the approach. will be targeted to a specific pathogen, but It Is applicable to several different pathogens. For example, an approach may be used to develop therapeutics against 20 different pathogens"
3. Professor Ron Taylor
This project started in May 1996 at the University of Virginia. Taylor and his colleagues developed a heteropolymer that functions on the one end to connect to the CR 1 site of the red blood cells, while the other end is tailored to the specific pathogen.
Let’s take a look at the co-authors of the March 17th Nature letter:
I realised, to my surprise, that I had already encountered 3 of the 5 co-authors & they were not people whose work had impressed me on identifying the origins of diseases
3. Eddie Holmes
"It is therefore possible that he is unconsciously sympathetic to Chinese colleagues, and sensitised to avoiding the causing of embarrassment to his hosts"
New documents back theory that Covid outbreak started in Wuhan lab
The emails uncovered by White Coat Waste Project suggest that viral DNA from “bats and other high-risk species” were sent to Wuhan between 2017 and 2019.
Just stating the obvious that THE FIRST CASE WAS NOT IN DECEMBER exposes the mendicant analysis of that recent piece, which feeds of the scraps of data left by China and then props itself up on odd logical shortcuts.
Useful Point by @baobaoxiaoliao
Dr.Worobey, here are some information you might interest in. In the early stage of the outbreak, China Gov only allows patients with Market contact history to receive tests. Is that a bias that can cause misinterpretation?