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18 Dec, 5 tweets, 4 min read
Given that early initiation of exercise after stroke is often advocated, the authors conducted this meta‐regression analysis with the primary objective of examining the association between time elapsed after stroke to initiation of exercise training and clinical outcomes.
- The number of adverse events in studies that were started within the first month after stroke was concerning, suggesting careful application of exercise training in the early phases.
- The time window for improved outcome in 6‐minute walk distance related to exercise training may span longer time periods than previously thought, and may fall within distinct post‐stroke phases, with no time association for other outcomes.
- Initiating exercise earlier (within 6 months) appears to be associated with a greater improvement in 6‐minute walk distance and to a lesser extent in fast‐speed 10 meter walk time (within 3 months), but not with CRF, balance, or comfortable 10 meter walk time.
Associations Between Time After Stroke and Exercise Training Outcomes: A Meta‐Regression Analysis (open access)

doi.org/10.1161/JAHA.1…

#exercise #Workout #TrainHard #GymLife #GymTime #muscle #strength #lift #cardio #hiit #stroke

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20 Dec
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20 Dec
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"Our study has three main findings...
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This one found that prolonged physiological and supraphysiological hyperinsulinemia can induce blunted acute insulin signaling, reduced insulin-stimulated glucose uptake, transcriptomic changes, and affect genes in insulin signaling pathways.
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