This picture paints about 3000 words.
🔴 Vaccinated

🔵 Unvaccinated

⚫️ Vaccine effectiveness versus hospitalization continues to remain strong now that Omicron is dominant in New York State
While I cannot sit and write 3000, here’s a few: Vaccines work. The COVID-19 vaccines are extremely effective at preventing serious illness, hospitalization, AND death.
Comparing the rates of COVID-19 hospitalization between fully-vaccinated and unvaccinated people using age-adjusted vaccine effectiveness, fully-vaccinated New Yorkers remain strongly protected against COVID-19 hospitalization.
Across the time period of analysis, fully-vaccinated New Yorkers had between an 90.2% and 95.7% lower chance of being hospitalized with COVID-19, compared to unvaccinated New Yorkers.
In this analysis, fully-vaccinated is defined as an individual who:
•Has received one of the three vaccines currently authorized by the FDA: Pfizer-BioNTech, Moderna, and Janssen/Johnson & Johnson.
•Is 14 days or more past the final dose of their original 2-dose
(Pfizer-BioNTech, Moderna) or 1-dose (Janssen/Johnson & Johnson) series.
•Fully-vaccinated people may have received additional or booster doses, which are NOT specifically accounted for in this analysis.
•For the purposes of this analysis, cases are defined at the person-level (1 case per person) and hospital admissions are defined at the event-level (multiple admissions with COVID-19 possible per person).
This directly comes from New York State COVID-19 Breakthrough Data for current estimates of cases and hospitalizations by vaccine status, and vaccine effectiveness. THIS IS PER 100,000. coronavirus.health.ny.gov/covid-19-break…
Again, that black line above is vaccine effectiveness versus hospitalization, which CONTINUES to remain strong even now that Omicron is dominant in New York State.

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More from @sailorrooscout

10 Jan
This picture paints about 3000 words.
While I cannot sit and write 3000, here’s a few: Vaccines work. The COVID-19 vaccines are extremely effective at preventing serious illness, hospitalization, AND death.
Sources
Image: @PaulMainwood- please do be sure to read his analysis as it is EXTREMELY informative (Yes, I asked for permission to use this!)
Report and Data: icnarc.org/Our-Audit/Audi… & icnarc.org/DataServices/A…
Read 6 tweets
8 Jan
Just a heads up. Regarding “Deltacron” or the “new variant” out of Cyprus. Please be aware those sequences being reported by media outlets right now appear to be due to contamination. It is NOT a new variant.
Per @PeacockFlu “they do not cluster on a phylogenetic tree and have a whole artic primer sequencing amplicon of Omicron in an otherwise Delta backbone.”
When processing several COVID samples at the same time, procedural failures can occur, and contaminations between samples with different variants occur. As @wanderer_jasnah says, it is PCR recombination due to contamination. Usually computational analysis can detect these flaws.
Read 11 tweets
7 Jan
A new analysis out of the CDC shows just how extremely effective COVID-19 vaccines are against COVID-19 associated hospitalization and death. Among 1,228,664 fully vaccinated individuals across the United States, 185 (0.015%) had severe illness and 36 (0.0033%) died. 🧵
Using data from 465 facilities in a large U.S. health care database, this study assessed the frequency of and risk factors for developing a severe COVID-19 outcome after completing a primary COVID-19 vaccination series, defined as receipt of 2 doses of an mRNA vaccine (BNT162b2
[Pfizer-BioNTech] or mRNA-1273 [Moderna]) or a single dose of JNJ-78436735 [Janssen (Johnson & Johnson)] ≥14 days before illness onset. Severe COVID-19 outcomes were defined as hospitalization with a diagnosis of acute respiratory failure, need for noninvasive ventilation (NIV),
Read 8 tweets
5 Jan
“In the United States, mortality trends typically trail case trends by about three weeks- which means the Omicron surge, which began more than a month ago, should be visible in the death counts. It isn’t yet.”

Let’s talk about that. 🧵
NOTE: Source for ALL the information above AND in this thread can be found here. I highly recommend David Leonhardt’s “The Morning” Newsletter.
nytimes.com/2022/01/05/bri…
“The details of the Omicron variant are becoming clearer, and they are encouraging. They’re not entirely encouraging, and I will get into some detail about one of the biggest problems- the stress on hospitals, which are facing huge numbers of moderately ill COVID-19 patients.”
Read 14 tweets
3 Jan
Guys, B.1.640.2 isn’t new. It actually PREDATES Omicron. It's a sub-lineage of B.1.640- which caused some concern back in mid-November but couldn’t even compete with Delta. B.1.640.2 was first sequenced OVER a month ago and was officially recognized as a lineage in December.
As Tom points out, there haven’t been any new sequences uploaded since before Christmas and this variant has had a decent chance to cause issues but never really materialized. It’s been classified as a Variant Under Monitoring by WHO since November. Let’s focus on Omicron.
If you need background on this I went over it all here. Approximately THREE days ago.
Read 14 tweets
3 Jan
A CWRU School of Medicine study of 577,938 pediatric and adult patients shows first time SARS-CoV-2 infections occurring at a time when Omicron was rapidly spreading were associated with significantly less severe outcomes than first time infections when Delta predominated. 🧵
It is IMPORTANT to note severity of disease in humans is NOT determined only by virus replication but also by the host immune response to the infection. Make sure you are PROTECTED. Source for the information above can be found here: medrxiv.org/content/10.110… PLEASE NOTE. Image
Currently, data on the severity of the disease caused by the Omicron variant compared with the Delta variant has been limited. Here, researchers compared 3-day risks of emergency department (ED) visit, hospitalization, intensive care unit (ICU) admission, & mechanical ventilation
Read 15 tweets

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