Those Nerdy Girls Profile picture
Jan 27, 2022 17 tweets 8 min read Read on X
1/ Q: Are cases peaking? That means it’s all downhill from here, right?

A: Sort of…. Remember that even if cases come down as quickly as they rise, there will be as many cases *after* the peak as before (think area under the curve).

dearpandemic.org/are-cases-peak…
2/ ➡️ And if the downward slope is *slower* than the rise, we will see *more* cases during the decline from a surge.
3/ Burning fast could be a silver lining of super transmissible #Omicron. Cases rose & fell quickly in S. Africa (w/ hospitalizations & deaths still lagging). The UK appears to have turned the Omicron corner. Many US states appear past their peak in cases, w/ regional variation:
4/ When cases peak, it can feel like we are in the clear. It would be welcome news if Omicron falls as fast as it has risen. The Nerdy Girls are cheering on that “exponential decay”. But we do need to temper this feel-good moment with a bit of caution.
5/ Even on the ⬇️side of a steep peak 📉, there are A LOT of cases.

That feeling of everyone having COVID will likely stick around a bit longer. This means your chances of being exposed are still high, even if those chances are getting smaller rather than larger each day.
6/ We also need to be aware that the fall may *not* be as fast as the rise in cases. What starts as a decline can easily turn into a high plateau. The UK is a bit ahead of most of the US in its Omicron wave, but recent big declines are now leveling off at still high levels:
7/ This is reminiscent of the Delta wave in the UK which never really came down from its high plateau over the summer after some initial fall from the peak. Denmark is showing that a seeming decline in cases can swiftly turn around into an even higher peak.
8/ Where is it all going?

Like most public health scientists, we are completely done making predictions. This pandemic has humbled everyone.
9/ But the shape of the curve is not determined purely by nature- human behavior still plays an important role. w/o formal restrictions, UK mobility data showed that people voluntarily changed their behavior a lot & went out less as Omicron surged in Dec. ft.com/content/dea539…
10/ When cases go ⬆️ people step up their precautions such as masking or testing before gatherings. These small adaptations can add up big at the population level & slow the spread, contributing to getting past that ever-important peak. BUT—the opposite is also true.
11/ While getting past the peak is psychologically soothing, don’t use it as an excuse to kiss strangers and throw all caution to the wind.
12/ It’s natural to have an optimism bias—if cases are moving in the right direction, we feel comfortable relaxing some of our precautions. But relaxing too much can put us individually at risk while cases are still super high & put the brakes on that downhill momentum.
13/ As mentioned above, if the downward slope is slower than the rise, we will see *more* cases during the decline from a surge. More cases still mean more hospitalizations and deaths—and the U.S. is currently seeing more than 2000 COVID-19 deaths A DAY.
14/ In weighing up your own risk budget, keep an eye on absolute levels in your local area, not just whether cases are declining or not (spoiler alert-they are still high EVERYWHERE).
15/ We recognize that for many who are boosted or not high risk themselves, your daily decisions may not change much at all. On the other hand, the immunocompromised & those with kids in school may feel very vulnerable. scientificamerican.com/article/latest…
16/ If you are high risk, it’s worth holding steady a bit longer until that downhill slide of the curve gets even more momentum. As a bonus, the more people–high risk or not–who make those “tiny wise decisions” the faster & steeper that “exponential decay” will be.
17/ So that means that on the downhill is when we want to ….STEEPEN THE CURVE! 📉

Despite all the rhetoric, we still are in this together.

Love,
Those Nerdy Girls

#SteepenTheCurve #ExponentialDecay #AreaUndertheCurve #Omicron #TinyWiseDecisions

dearpandemic.org/are-cases-peak…

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More from @DearPandemic

Dec 22, 2022
How can I stay safe during the holidays?

➡️Think in terms of harm reduction. Don’t let the perfect be the enemy of the good.

dearpandemic.org/safe-holidays/

#covid #rsv #flu #HolidaysAreComing

1/
2/ Just in time for Christmas, #COVID is again on the rise.

#Flu and #RSV may be peaking—but remember that there are often as many cases *after* a peak as before it.

dearpandemic.org/are-cases-peak…
3/ How can we enjoy moments w/ family & friends & lower the risk of illness?

💥 Small steps you take to reduce risk are worthwhile. A little bit better…is a little bit better.

Prevention steps that work for COVID will reduce the risk of RSV, flu, & many other nasty viruses.
Read 14 tweets
May 4, 2022
1/ Q: Has almost everyone been infected with COVID by now?
A: Recent estimates suggest around 58% of the population in the US and over 70% in England have been previously infected, with BIG increases during the Omicron wave.

dearpandemic.org/numbers-infect…
2/ A recent @CDCgov MMWR report estimated seroprevalence from a convenience sample of blood collected for medical tests.

➡️Roughly 58% of Americans showed evidence of previous SARS-CoV-2 infection in their blood by Feb '22.

cdc.gov/mmwr/volumes/7…? Image
3/ ➡️ During the Omicron wave from December 2021-February 2022, this estimate increased from 33% to 58%.
➡️ Rates vary a lot by age, ranging from 33.2% for those over age 65 to 75% for those under age 18.

cdc.gov/mmwr/volumes/7… Image
Read 15 tweets
Apr 29, 2022
1/Q: Did getting exposed to fewer germs for the last 2 years weaken our immune systems?

We've been hearing this question a lot.
dearpandemic.org/fewer-germ-exp…
2/ Not likely. If your kids are suddenly getting sick a lot, this is likely due to “catching up” on exposures rather than a weakened immune system.
3/ Many families w/ young kids have been hunkered down for the better part of 2 years– a good % of a young child’s entire life. While isolation had *many* downsides, we can agree that not having to suction snot out of infant noses or clean up norovirus puke was a happy upside.
Read 18 tweets
Dec 30, 2021
1/ Q: Case numbers are jumping QUICK! What should I be doing?

A: Share your gifts without sharing COVID. Helpful gestures come in many shapes.

dearpandemic.org/what-should-i-…

#Omicron #ThoseNerdyGirls
2/ One HUGE help: Cancel non-essential plans.

Unfortunately, this includes New Year’s Eve plans. The perfect storm of a new variant & holiday get-togethers is hitting communities & health care w/ FORCE! Testing is in short supply.
3/ Health care is under extreme pressure with surging cases. If you can avoid even one additional contact, you are helping. This is a temporary and urgent request (from a health care provider).

#MedTwitter #HCWs @IMPACT4HC
Read 10 tweets
Dec 21, 2021
1/ Q: Is it true that #Omicron is less severe than previous variants?

A: We HOPE so, but we don’t know yet. The evidence so far is mixed.

dearpandemic.org/is-omicron-les…
2/ We are WAY past due for some good variant news. But pinning our #Omicron hopes on a less virulent variant is not wise for 2 reasons:

1) It might not be less severe in those who are “immune naïve” (neither vaccinated nor with a previous infection—still millions of people).
3/ 2) Many more infections *even* if less severe can still lead to an avalanche of hospitalizations and deaths, and the risk of long Covid.

@AdamJKucharski raised this last December w/ the rise of Alpha:
Read 25 tweets

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