Mia Malan Profile picture
Mar 4, 2022 7 tweets 5 min read Read on X
[Thread] 1. What's happening with #COVID19 hospital admissions in SA?

Waasila Jassat, @nicd_sa:
- Over the past 14 days, admissions have decreased between 18% and 59% in all provinces
2. Your risk of hospitalisation due to an #Omicron infection is about 50% lower than in Wave 1,2,3 in SA (the risk for each wave = slightly different)

Most admissions in Wave 4 (#Omicron) = people between 20 and 39 years. In Wave 1,2,3 = admissions of people between 40 and 70.
3. Even though there were more admissions among younger people during our #Omicron wave, people's risk of admission still increased with age. So the older you were, the more likely you were to get very sick with #COVID.
4. Jassat:

Once you're admitted to hospital for #COVID19 in SA, your risk of dying of it is much higher if you were admitted to a public sector hospital than a private sector hospital.
5. Jassat:

In SA, the most common comorbidity associated with a #COVID19 patient who gets hospitalised, is hypertension (high blood pressure). The second most common comorbidity is diabetes and patients almost always have more than one comorbidity.
6. Jassat:

Comorbidities associated with #COVID19 hospital admission = change with age.

For people between 20-39 years (sexually reproductive years) HIV = most common comorbidity. For people of 40+ hypertension/diabetes = most common (lifestyle diseases = more common in 40+)
7. Jassat:

Ultimately, age is the strongest indicator of how sick you will get with #COVID19 - more so than any other comorbidity.

In SA, non-white people's risk of death of COVID = higher than white people's

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More from @miamalan

Jul 24
🧵1. BREAKING: The peer-reviewed results of the study of a 6-monthly jab, #lenacapavir, in which not a single of the 2134 women between 16-25 years who received the jab contracted #HIV, were released at #Aids2024.

Find the full study here:

bhekisisa.org/wp-content/upl…
Image
2. Women often find it hard to adhere to daily #oralPrEP. In the Purpose 1 trial, 91.5% of women returned on time for their next #lenacapavir jab at 26 weeks and 92.8% at week 52. Image
3. Only 4 women out of 2134 (0.2%) who received #lenacapavir dropped out of the trial because of injection-site reactions. Image
Read 15 tweets
Jan 17
[Thread] 12 things to know about the the proportion of pregnant women infected with #HIV from SA’s latest antenatal HIV survey. The survey is conducted by the @nicd_sa.

(Analysis of our 95-95-95 goals in my next thread later in Jan).

1/12 Image
2. What is the antenatal #HIV survey?

1. It measures the % of HIV+ pregnant women between the ages of 15 + 49.
2. Only women using state pregnancy clinics take part.
3. The survey has been conducted each year between 1990-2015, then in 2017, 2019 +2022. Image
3. How many pregnant women between 15-49’s blood was tested for #HIV? 37 828 out of 40 542 collected samples.
- 37 7171 = Black African women
- 37 541 didn’t live with the dad of their child
- 35,635 of dads were 5 years+ older than moms (this makes them more likely to get HIV) Image
Read 12 tweets
Jan 10, 2023
JUST IN [Thread]:
1.@healthza's Lesley Broomberg:
An extra #COVID19 booster jab for people of 18+ in SA will become available towards the end of JANUARY
- People of 50+ qualify for a 5th dose
- People of 18+ qualify for a 4th dose
2. Lesley Broomberg: Can you mix and match with additional boosters? Yes. You can choose whether you want a #JnJ or #Pfizer booster.
3. Lesley Broomberg:
Will teens of 12-17 qualify for boosters? Not at this stage. Why not? The #VMAC = not recommended booster doses for 12-17, based on an understanding that the protection provided by 2 #Pfizer doses = adequate, as 12-17 = @ low risk of severe #COVID19 illness
Read 5 tweets
Jan 10, 2023
[Thread] #JoePhaahla:
- Genomic surveillance Network reported the detection of the new subvariant XBB.1.5 in SA of a sample of a patient tested on 22 Dec
- Details of the patient = not known, it was a random sample taken for testing
- XBB.1.5 = also common in US
2. XBB.1.5 = common in US
#JoePhaahla:
- 97%+ of #COVID19 cases worldwide = still #Omicron
- XBB.1.5 cases = no major change in hospitalisations or deaths
- Immunity of SAs (vax and natural immunity) = still strong, so that is why we haven't seen much change in terms of hospital admissions/deaths
Read 5 tweets
Dec 13, 2022
🧵1. SA's @aspenpharma will be making 4 jabs (fill + finish) — pneumococcal, rotavirus, meningococcal, hexavalent — from 2023.

How will they finance this?
With a $30 million grant from @CEPIvaccines + @gatesfoundation.

Which APIs will Aspen use?
India's Serum Institute's
2. Why is it NB that an African company makes these jabs?

#Africa imports almost all its jabs. #COVID19 showed us this results in Africa being last in line to get vaccines during pandemics. The grant to Aspen is 1 of the 1st steps to change that.
3. What's the goal?

By 2040, the African Union wants #Africa to make 60% of the jabs the continent uses.

Why?
So that Africa is better equipped 2 respond 2 outbreaks (by developing the ability to make jabs + have technology in place to also make new jabs during pandemics).
Read 6 tweets
Dec 2, 2022
🧵1. BREAKING: @SAHPRA1 has confirmed the registration of the #HIV prevention jab, #CABLA in South Africa. On Thursday, #ViiVHealthcare issued their statement. ImageImage
2. Who can use the jab? @SAHPRA1 didn't specify restrictions for use in their statement, only that it is "a highly effective option for people at substantial risk of #HIV infection." Image
3. How does the jab work? It uses an #ARV called cabotegravir that prevents #HIV from replicating and entering someone’s cells. It’s taken every two months. Read my latest story for more. bit.ly/3ER7ejq
Read 5 tweets

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