44 year old male, HIV (+), non adherent to antiretroviral therapy (CD4 120) presents for evaluation of this lesion:
๐ค The most likely microorganism responsible for this finding is:
๐ชก1/5 B) Treponema Pallidum
This patient presents with a syphilitic gumma in the setting of tertiary syphilis
Although gummatous disease is uncommon, HIV patients have an increased risk of developing gummas most frequently in the oral cavity, skin or a viscera.
2/5 HHV-8 presents as Kaposiโs Sarcoma, the lesions are purplish, reddish blue, or dark brown/black macules, plaques, and nodules.
3/5 CMV can present as a painful tongue ulceration
4/5 MAC has no tongue involvement, and if so, other infectious causes should be ruled out.
37 y/o F PMHx of lupus nephritis complicated by ESRD s/p living-donor kidney transplant 5 months ago, who presents with 3 days Hx of dysuria, hematuria, pelvic pain and subjective fever
2/5 She denies recent lupus flares. Patient is taking tacrolimus, mycophenolate, prednisone and TMP-SMX. Vaccinated against COVID-19x3. No sexually active for the past year. PreTransplant HIV,CMV,HepBC, adenovirus, Toxo and trypanosoma serologies (-) for both patient and donor.
3/5 On presentation BP 140/90 HR 78 RR 16 T 101 O2Sat98% RA. Hydrated mucous membranes. Clear chest to auscultation, normal heart sounds. Abdominal scar healed no signs of infection. Tenderness to palpation of hypogastrium. No CVA tendernesses.