Nath's back, finding a chronically activated immune response causing neuronal injury in the brains of #pwLC. It explains why it's taken him forever to publish his big #MECFS study, but the good/bad news is he thinks the same thing's happening in #pwME. 1/4 healthrising.org/blog/2022/07/1…
This looks very similar to what Komaroff et al suggested was happening in #MECFS 30 years ago: "patients may have been experiencing a chronic, immunologically mediated inflammatory process of the central nervous system." 2/4
pubmed.ncbi.nlm.nih.gov/1309285/
pubmed.ncbi.nlm.nih.gov/1309285/
Nath also found the same widespread punctate hyperintensities in the microvasculature of brains which first started showing up in MRI scans of #pwME in the 80s (see J. Goldstein) and were routinely dismissed by neurologists as insignificant. 3/4 healthrising.org/blog/2021/01/2…
Nath says these vascular injuries are usually seen in strokes and other inflammatory diseases and could well be evidence of a neuro-inflammatory process in LC. It'll be interesting to see if his long-awaited intramural study finds the same thing in #MECFS. 4/4
• • •
Missing some Tweet in this thread? You can try to
force a refresh
