just having a look at the raw data output and this stands out. most participants report no health problem that affected their day-to-day living prior to the offending vaccine
after the offending vax general health was reduced to being very poor
even those who had no indication something could go wrong, who led completely unrestricted lives, had their world turned upside down after vaccination
many already chronically ill folk seem to have on their mind that they might react badly (and there was a distinct lack of chronic illness patients in trials), and indeed it seems ME and long COVID patients have a high prevalence of severe reactions (maybe around 20 %).
but for many who the vaccine ruined, such side effects were completely unexpected. in other words, just like #LongCovid and post-infection syndromes (e.g. #MECFS, #LymeDisease), a severe reaction could hit any of us
Had an appointment with my best dr today. The only dr i fully 100 % trust. Some points for #medtwitter:
1. I trust him because he believes me, first and foremost
2. He knows i struggle being upright and with light so he turns the lights down & preps a couch for me to lie on
3. He knows i am clinically vulnerable so wears a respirator, and if med students/whoever are observing, he gets them to mask up too. Also has the window cracked for ventilation
4. Even though i see him for very specific things, he provides space for me to talk through how EVERYTHING has been since we last spoke. He writes up any symptom changes in my notes so its an accurate record. This is important as it clearly shows i am still highly symptomatic
Update to the @NHSScotland #POTS pathway disaster:
In EDIT 7, I went through a bunch of emails & one showed Dr Claire Taylor was invited to help on the pathway. I wanted to know Dr Taylor's involvement so I FOI'd any emails between her & NSS/POTS groups👇🏻 dontbelievehype.co.uk/covid-%26-vacc…x.com/angryhacademic…
As you will see in the blog, Dr Taylor had no substantive involvement. Having seen the pathway, this is no surprise. She was clearly unable to attend meetings due to her clinic. But what is maybe a surprise is that Dr Taylor absolutely hammered NHS Lothian's approach to POTS
Her critique was sent at a similar time to my complaint, so maybe our collective efforts were the trigger towards the pathway being retracted.
Brief recap on methods:
This was a blinded randomised placebo controlled n-of-1 trial. What does that mean?
Blinded: this means I did not know if I was truly getting blood taken, or if it was sham (placebo) phlebotomy
To do this, a suitably qualified friend would take my blood as normal using either proper tubes (real), or dudded tubes (sham). I was blindfolded & wore noise cancelling headphones so didnt know what I was having done, & tubes were disposed of before I took the blindfold off
💊 Examples: Sodium cromolyn, ketotifen, vit C, quercetin, luteolin
🧪 Main mechanism: Unlike antihistamines, which block the histamine receptor as their primary mechanism of action, mast cell stabilisers help prevent mast cells from spewing out their contents ("degranulation")
In MCAS, this degranulation is inappropriate, with mast cells reacting to benign triggers such as foods, air pressure, or scents (among many other things). Therefore, stabilising mast cells can help with some histamine issues...
Mast cell activation syndrome (#MCAS) & histamine intolerance are common features for many #longcovid & #PostVac patients. 🧵on antihistamines which are commonly used in MCAS & histamine intolerance. (I will do another post on mast cell stabilisers) lc-sc.co.uk/bodily-systems…
There are different types of antihistamines with different actions, but they all block a histamine receptor so histamine can no longer attach to the receptor & cause chaos. I.e. antihistamines do not stop histamine production, they just stop histamine from working properly
🧪 Main mechanism: These work by blocking the H1 receptor, which has roles in hypersensitive reactions (e.g. wheezing, itching, coughing, blood pressure dropping)...