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Jul 29 • 4 tweets • 3 min read
Annie Luetkemeyer (@annieluet) reports doxycycline PEP reduces risk of STIs for gay/bi men & trans women on #PrEP (incidence 32% vs 11%) & #HIV+ (31% vs 12%) — even more so for those who used it consistently. @UCSF #AIDS2022
DoxyPEP led to reductions in #gonorrhea, #chlamydia & #syphilis. Analysis of antibiotic resistance & gut microbiome is underway. #AIDS2022

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More from @LizHighleyman

Liz Highleyman Profile picture
Jul 30
And now, the Future of #HIV Media Coverage -- plus COVID & I won't be surprised if they mention #monkeypox. With @picardonhealth, @sciencecohen, @sarahboseley, @boosulyn, @SipokaziF, @apoorva_nyc, @rkhamsi & @ProfSharonLewin #AIDS2022 Image
.@sciencecohen: There used to be AIDS journalists, that's rare now. With COVID, every reporter became a health reporter. Public more informed about science than ever before. But, adds @picardonhealth, they're more misinformed as well. #AIDS2022 Image
How to balance COVID -- & now monkeypox -- with ongoing issues like #HIV/#AIDS?
@apoorva_nyc: When people stop seeing a disease as a threat to themselves, they don’t pay attention anymore. How do we get people to care about something that affects a specific population? #AIDS2022
Read 10 tweets
Liz Highleyman Profile picture
Jul 29
Important🧵from @thrasherxy. We've all seen the excerpts posted here from historical descriptions of #monkeypox transmission & symptoms, but the current outbreak among gay/bi/trans/MSM looks very different. 1/
It's quite possible low-level MPX spread is happening via traditional transmission routes while *at the same* time an explosive outbreak is occurring, via different routes, in a specific population. 2/
We've seen something similar with sexually-associated outbreaks of hepatitis C among gay/bi/MSM. This suggests it's possible for a pathogen to be both an STI & not an STI simultaneously (Schrödinger's STI?) 3/
Read 4 tweets
Liz Highleyman Profile picture
Jul 29
.@CAPublicHealth has released new #monkeypox data with some eagerly awaited demographics. Still overwhelmingly gay/bi/MSM. Among 786 cases are 5 trans men, 3 cisgender women, 3 trans women & 2 non-binary. 45% white, 36% Latino, 9% Black & 6% Asian.
cdph.ca.gov/Programs/CID/D… ImageImage
According to census.gov, #monkeypox distribution for Latino & Black people isn't that far off from statewide population percentages (40% & 7%, respectively. But other sources put the Latino population share much lower, at around 19%.
But statewide numbers can mask local variation. One of the first thing I noticed in SF's demographics is that ~30% of monkeypox cases are among Latinos -- about twice their share of the city's population.
sf.gov/sites/default/… Image
Read 5 tweets
Liz Highleyman Profile picture
Jul 29
A Southern California man appears to be cured of #HIV after undergoing a stem cell transplant to treat leukemia, Dr. Jana Dikter of @cityofhope reported this week at #AIDS2022. @eBARnews
ebar.com/story.php?ch=N…
This risky procedure isn't suitable for most people with HIV, it offers clues for more feasible approaches. "These cures are no longer anecdotal - we now have a real case series," said Dr. Steven Deeks of @UCSF . #AIDS2022
.@iasociety put journalists in a bind by holding press conferences so early. Dikter gave a summary at Wed press briefing & @cityofhope issued a press release, but her actual presentation isn't until Monday. Of course, mainstream media reported it right away after the presser.
Read 5 tweets
Liz Highleyman Profile picture
Jul 28
SF declares #monkeypox a state of emergency. SF has a large & politically powerful LGBT community & one of the largest MPX outbreaks in the US on a per capita basis. 1/
SF was, I believe, 1st US city to issue an emergency & take steps like a shelter-in-place order for COVID. Not sure new emergency means in practice. What we need is more vaccines, but that’s up to the federal govt. 2/
I’m quite sure @SF_DPH (run by a gay man) won’t take steps the LGBT community opposes. I don’t see a raging debate within that community, or btwn that community & officials, like we did when the city shut down bathhouses to curb AIDS in the early ‘80s.
Read 8 tweets
Liz Highleyman Profile picture
Jul 27
City of Hope Patient is older than the few other people previously cured after stem cell transplants & he's been living with #HIV longer, suggesting this approach may be feasible for more people with both HIV & cancer. #AIDS2022 @cityofhope #AIDS 1/
bit.ly/3zDttb6
This follows the cures of @TimothyRayBrown, @londonpatient, the New York Patient -- & some count the Dusseldorf Patient -- making this the 4th or 5th such case. @pozmagazine 2/
poz.com/article/patient
Stem cell transplants are too risky to be an option for most people living with #HIV, but these findings provide clues that could help researchers develop more widely applicable approaches for long-term HIV remission. 3/
Read 4 tweets

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