Thread by @FLAHAULT

1/9 - “#COVID19 significantly increases the risk of developing dementia, psychosis and brain fog two years after infection, according to the first extensive study of the disease’s persistent neurological and psychiatric effects.”
ft.com/content/d01510…

2/9 - “#LongCovid, often defined as symptoms experienced for 12 weeks or more after a #COVID19 diagnosis, encompasses a range of symptoms from fatigue and breathlessness to problems related to the brain, such as a lack of mental clarity. It could affect >100mn people worldwide.”

3/9 - “Researchers at Oxford analysed the electronic health records of 1.25mn pple diagnosed with Covid and a matched control group of an equal number of patients who had other respiratory infections. The data, covering 14 brain disorders, were provided by the US-based TriNetX.”

4/9 - “The impact of #COVID19 was most marked in people aged 65 and over, among whom 4.5% developed dementia over the subsequent two years, compared with 3.3% of the control group. For psychotic disorders, the figures were 0.85% in #COVID19 patients and 0.6% in controls.”

5/9 - “The most significant increased risk among younger adults aged 18 to 64 was cognitive deficit, sometimes called brain fog. It affected 6.4 per cent of people who had #COVID19 during the previous two years and 5.5 per cent of controls.”
thelancet.com/journals/lanps…

6/9 - “The results have important implications for patients and health services as they suggest that new cases of neurological conditions linked to #COVID19 infection are likely to occur for a considerable time after the pandemic has subsided.”

7/9 -“Children were 2x as likely to develop epilepsy or seizures - 2.6% developed the condition after #COVID19, against 1.3% after another respiratory infection. And at 3-fold increased risk of psychotic disorder, even though this is rare - 18 in 10,000 in the 2 yrs after Covid.”

8/9 - “The emergence of the #Delta variant was associated with an increase in risk for several conditions. With #Omicron, although we see much milder symptoms directly after infection, similar rates of neurological and psychiatric diagnoses are observed as with #Delta.”

9/9 - “The findings suggested that the burden on healthcare systems may continue even with variants that are less severe in other respects. We know much less than we think we know about #LongCovid. There are many more questions than answers.”