📺🧵Key takeaways from @IndependentSage @DrGrahamLJ on the long term risks of #SARSCoV2:
🔹Covid is a blood vessel disease
🔹1/2 billion virus in 1tsp of saliva
🔹Importance of mouth hygiene
🔹Viral load in mouth predictor of acute illness
Clear explanation by @Sunny_Rae1 of #SARSCoV2 as:
🔹a blood vessel disease
🔹 pathophysiology of microclots & endothelial damage
🔹present in #LongCovid & a lesser degree in 'recovered' patients
@DrGrahamLJ do you think this is another reason why people with #EDS#hEDS (Hypermobility) are more susceptible to Covid/LongCovid? Bleeding gums is common in these patients and it's another line of immune defence gone?
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UPDATE: Complaint about CISCO21 Long Covid Exercise Study
🚩Serious risk of patient harm
RESPONSE: PEM is primarily assoc. with other forms of exercise
Resistance bands do not rely on mitochondria
🤦♀️PEM can occur after any exertion
Axcella used resistance bands=mito dysfunction
🚩No screening for PEM
🚩 Inadequate consultation of scientific literature in #ME#PEM
RESPONSE: we've done PPI & PROMS 😬 (this literally doesn't make sense)
🚩Lack of consideration to personal testimony that exercise does not help conditions with PEM
RESPONSE: we've done PROMS, open hypothesis - we're open to it not being helpful, there's no evidence that exercise can cause permanent damage to C19 patients
The psychologisation of a disease occurs when it is believed that psychological states cause or drive or sustain symptoms of that disease.
🚪Front door psychologisation: it's in your head, causes the disease
🚪Back door psychologisation: influences, sustains, drives the disease
Gez & Danny's book looks fantastic and a real resource for those with & without #LongCovid.
Sincerely hoping that this view that: "there is a huge degree that our emotional state can drive symptoms by sending us into a state of sympathetic overdrive"
is not referenced...
Gez is more than welcome to have this as a personal view. Yet it is the reasoning that those who psychologise the disease can take
It is why we have 'integrated' care & research that focus on CBT as stress and anxiety are seen are sustainers of the illness.
There is no evidence
🧵Serious Red Flags for the #CISCO21#LongCovid Study
Researchers please listen to patients concerns & expand your knowledge to the history of #MECFS
You have a chance to stop patient harm
1. No mention of #PEM#PESE in the literature
After repeatedly asking if they screen for #PEM or take this into account - they have not responded in the affirmative.
This is the nub of the issue
75% of #Longhaulers have #PEM
46% are eligible for an #MECFS diagnosis
This means that our bodies cannot process exercise - think sugar diabetes
There is no magic where by giving us exercise because we can't do it means we will magically be able too
Super @BBCNews coverage of possible breakthrough treatment that dissolves the microclots, HELP Apheresis. Superb interview by @doctorasadkhan who tells it like it is!!! ✊ Let's hope this works, fast track funding is given & it's rolled out to all 🤞🙏
Vid 1: 🧵