This one suggests that just one single meal lower in protein content may lead to increases in daily total caloric consumption in order to experience the same level of fullness and hunger suppression.
- "Indeed, we found that the average macronutrient composition of the SSMD (Self-Selected Meal Day) meals was lower in both protein and carbohydrate, and higher in fat, than the study diet...
"...In addition, the daily caloric intake on the SSMD was 14% higher (or an average of an extra 262 total daily calories, P<0.001) than baseline daily intake...
"...This additional calorie intake occurred, however, without perceived change in fullness or hunger...
"...In other words, for participants to experience the same level of fullness and hunger suppression on the SSMD as during the preceding baseline feeding study days, they needed to consume an additional 262 cal...
"...These data support the concept of a central appetite set point in which the number of calories needed to achieve a level of expectant fullness and hunger, or meal satisfaction, is infuenced by diet composition, and is sensitive enough to respond to changes in a single meal."
- "We found that neither the change in the daily fat nor carbohydrate intake was associated with the increase in SSMD daily calorie consumption, but the reduction in protein intake was"
- "Upon resumption of the study diet that was, on average, higher in protein and lower in fat content than the SSM (Self-Selected Meal), daily calorie intake dropped significantly below baseline the day following the SSMD...
"...and remained non-signifcantly lower for the next 2 days...
"...These decreases in calorie intake in the days after the SSMD also occurred without changes in reported fullness and hunger scores and are consistent with a simultaneous restoration of enhanced satiety (and hunger suppression) at lower calorie intake."
TL;DR:
- Just one single meal with a lower protein content is associated with an increased daily total caloric consumption, and that seems to be happen in order to experience the same level of fullness and hunger suppression.
- The excess food intake that is assumably caused by a single meal lower in protein content seems to be only partially, and very slightly, compensated upon re-establishment of a diet that consists of invariably higher protein meals.
Self-selected meal composition alters the relationship between same-day caloric intake and appetite scores in humans during a long-term ad-libitum feeding study
Here, leisure-time sedentary behavior was associated with the risk of dementia incidence and mortality, but replacing it with a short duration of physical activity was associated with a decreased risk of dementia, with the effect being stronger in APOE ε4 carriers.
- The apolipoprotein E (APOE) gene is the strongest genetic factor modulating risk for Alzheimer's Disease and dementia.
This gene has three common alleles, the protective allele APOE ε2, the neutral allele APOE ε3, and the risk allele APOE ε4.
This systematic review and meta-analysis suggests that nut consumption is likely to reduce serum triglycerides in healthy adults with overweight/obesity, and LDL-c when incorporated in one's habitual diet.
- "Subgroup analyses for serum lipids revealed that the favorable effect of nuts on serum TG was more pronounced in population with a mean BMI <30 kg/m2 and in a follow-up duration <12 weeks...
"...Moreover, in the subgroup analysis based on the type of diet, nut consumption led to a significant decrease in LDL-C in those following a normocaloric diet."
This one in Iranian adults found higher dietary oxalate intakes to be associated with an increased risk of developing hypertension and chronic kidney disease, especially when consuming lower calcium intakes.
- Compared to high-calcium consumers, subjects with lower calcium intake (< 1180 mg/d) had a higher risk of both CKD and hypertension.
- Interestingly enough, no statistically significant association was observed between dietary oxalate and the outcomes in subjects who consumed dietary calcium above the median.
This systematic review and meta-analysis finds the triglyceride glucose (TyG) Index to be a reliable, effective tool that can be used for the screening of metabolic syndrome.
- "A significant association of the TyG index with MetS was reported in all included studies, indicating the potential reliability of the TyG index as a new index for screening MetS...
This one found an inverse association between folate intake and colorectal cancer risk, while identifying 3 genes with suggestive interactive effects between total folate consumption and colerectal cancer risk: GSTA1, TONSL, and AGA.
- An inverse association between folate intake and colorectal cancer risk was observed.
- The study also identified 3 genes with suggestive interactive effects between total folate consumption and colorectal cancer risk: GSTA1, TONSL, and AGA.
This study in Finnish twins finds that an unhealthy lifestyle during pubertal years (obesity, smoking, binge drinking, low levels of physical activity) is associated with accelerated biological aging in young adulthood.
- Both the class with the overall unhealthiest lifestyle and that with a high BMI were biologically 1.7–3.3 years older than the classes with healthier lifestyle patterns when DNAm GrimAge was used...
... and had 2–5 weeks/calendar year faster pace of biological aging when using DunedinPoAm.