In immunocompetent hosts, when chronic disseminated histoplasmosis occurs from pulmonary infection, oral ulcers, nodules, and vegetative plaques are common and dissemination to liver, spleen, bone marrow, and other organs is frequent. 3/4
The disseminated histoplasmosis seen in this case had no clinical evidence of immune suppression
The patient presented a deteriorated clinical condition, hypotension, electrolyte imbalance, and altered sensory that ended fatally perhaps due to adrenal insufficiency 4/4
Diagnosis is usually suspected on visualization of characteristic intracellular yeast (blastoconidias), the pathogenic or tisular form, with a clear rim and garnulomatous cellular infiltrate in tissue specimen or lymph node aspirate 3/7
@olaya_sm Con 🔍: Hiperqueratosis subungueal (&), borde distal irregular, zonas parduzcas de aspecto hemorrágico (&) y patrón multicolor de lámina ungueal con áreas verdes ($) y azul-negruzcas (*), y otras longitudinales amarillentas (→)
A 31-YO ♂️, sex with men, HIV treatment, HCV: in 2022, fever, cervical lymph nodes & erythemato-squamous papules, with umbilications & ulcerations, vesicles & pustules, & honey-colored crusts on the face, trunk & limbs including his palms & soles 1/7
Supportive care of Mpox was provided, namely,
✔️beta-lactams due to bacterial superinfection of the lesions,
✔️in addition to analgesia, which was initially administered with NSAIDs and then escalated to opioids. 3/7
A 32-YO ♂️ sex worker, sex with men unprotected, HIV under treatment: 20 lesions scattered throughout the body of umbilicated, erythematous, violaceous papules with central ulcerations & pustules, fevers, cervical & axillary lymph nodes 1/5
Mpox had been a neglected disease until May, 2022, and since then, there has been a notorious increase in the number of human monkeypox cases in non-endemic areas 3/5
An 86-YO ♂️, injury on his L leg 47 years prior, several debridements, skin grafts, & vein stripping procedures: chronic bilateral leg progressive ulcers.
Superficial🧫: multiple organisms including E. coli & coagulase➖Staphylococcus. 1/6
@Mercede49161978@ContinuumAEP@aepediatria El panadizo herpético empieza con sensación de hormigueo, y puede causar dolor intenso, eritema y edema del dedo; en ocasiones, fiebre y adenopatía.
Aparecen vesículas coalescentes en la falange, generalmente después de 2 o 3 días de comenzado el dolor. 3/8