Discover and read the best of Twitter Threads about #microbiology

Most recents (24)

1/ Happy Friday!
Today I am celebrating #scicomm! As of this week, I have contributed 21 articles to the @ASMicrobiology Bugs & Drugs blog! Here's a recap of some of these articles for those who love clinical #microbiology
#IDTwitter @ASCLS @CUAnschutz #MedEd @JClinMicro
2/ First, just a quick note on writing for @ASMicrobiology. Volunteering my time to write has been one of the highlights of the last 2 yrs for me! So grateful for the amazing Bugs & Drugs team, especially @JulieMarieWolf @JClinMicro @ScienceInTheDMV who took a chance on me.
#Publichealth piece discussing the yellow fever outbreak of 2015/16 in Africa & highlighting the amazing work of researchers working on fractional #vaccine dosing. It's an amazing story, full of impressive characters.…
Read 19 tweets
Today's talk now posted for my FAVOURITE topic:
How to study & learn clinical/medical #microbiology.
🧠What to know
🧠How we learn
🧠Free resources

🧵below & slides available free:

#IDTwitter #MicroMedEd #ASMCPEP #clinmicro #ASMClinMicro Title slide: Studying & learning microbiology Contact inform
This talk expands on content from my ASM post from June.…
... which outlined traits of experts & how we can use them to learn (eg. with visual tools):

👉These slides (summarized next) put this in the context of preparing for clin/med micro/ID exams.
2/14 Table: Traits of experts (vs. novices) and how visuals aid t

Your exam will have a syllabus & information about the exam format itself. These are key resources. But remember that you're preparing for both the exam and your career beyond that.

3/ Venn diagram: What you need to know for your JOB  vs. for yo
Read 14 tweets
1/ Proud to be a part of this hot-off-the-press #stewardship study examining time to blood culture positivity by pathogen and primary service. A joint effort by scientists at @ChildrensColo @CUMedicalSchool @CUAnschutz. Check it out #IDTwitter ! Summary 🧵…
2/ Some background:
* Historically, infants and children are given antibiotics until blood cultures are negative at 48-72 hours.
*Empirically treating is essential for children with bacteremia, but waiting for this negative BC period may be unnecessary.
3/ Why we did this study:
* Understanding the time it takes for blood cultures to become positive (with respect to certain organisms and subspecialties) can help shorten overall antimicrobial duration.

*Shortening duration= fewer adverse events, less resistance, shorter stays
Read 23 tweets
1/ These new interesting insights could provide answers for #MEcfs and #LongCovid.

"Researchers tracked antigens and other substances crossing the arachnoid barrier (known for his impermeability) but they found leaks in this particular area" #LeakyBrain…
2/ "Immune cells are waiting there. When these cells find a worrisome antigen, like one that suggests disease, they initiate a chain reaction that creates an immune response" #NeuroImmunology
3/ “Immune surveillance of the brain takes place. It’s absolutely normal, like in any other tissue,” said Jonathan Kipnis. “The only exception is that instead of this happening within the tissue, the brain pushed all its immune activity to its borders.”
Read 5 tweets
1/I want to take some time to share findings from our semi-recent PETACS study. This was a wonderful collaboration between @COpedsID faculty, survey designers, and #microbiologists across the US.
@JClinMicro @ASMicrobiology #ASMClinMicro…
2/ First, I want to emphasize that this project highlights many of the reasons I chose to pursue a #PhD in clinical & translational science. As a long-time microbiologist, I can say that the clinical lab doesn't often have a seat at the clinical effectiveness / research table.
3/ This project focuses on the tracheal aspirate culture- a diagnostic process that is greatly limited by contamination with normal respiratory flora, and which lacks consensus or standardization across labs and hospitals. @ASCLS @ASMicrobiology @ASCP_Chicago
Read 26 tweets
And so Day 3 of my story of God at work in my life as part of #OfGodAndMe #ThisNunsStory series. Yesterday mention of the book, The Silver Sword seems to have struck a chord with many so perhaps its not out of place to mention that today 7th April is #Worldhealthday 1/20
Ian Serraillier ended his talks by showing this photo with the words, ‘No child should ever again have that expression on his face’. My hope this the UK as host of the upcoming #G7 summit will prioritise Universal health care for all. #UCH 2/20
So back to my story. Living at home again and my dream of religious life gone out the window I applied and got a place for September at Brighton College of Education to do a cert ed in biological science & primary education 3/20
Read 21 tweets
After an amazing response last week, I’m super excited to LAUNCH TODAY my FREE #SciComm #YouTube tutorial series for #Scientists & #researchers across disciplines on how to create your own #animated #videos for #Science #Communication. Pls SUBSCRIBE & RT! 5 videos to start! 1/7 Image
Video 1 - SciComm: #Animation training for Scientists - A brief introduction to this #tutorial series 2/7

Video 2 - SciComm: Animation basics in #aftereffects – Part 1 - setting up, basic shapes, strokes and colours 3/7

Read 9 tweets
My name is Fancy and I'm taking part in the #GlobalScienceShow
Today I'm going to show you some of my #SciArt works combining industrial design to communicate science!

Check @GlobalSciShow and follow for the whole show ✨🔬✏️👋🏽

#scicomm #comunicacienciachile #industrialdesign
I’ve always been passionate about #science but I also loved #art and wanted to create products, so I studied #industrialdesign, art and #architecure and now I use different techniques & disciplines I’ve learned to express ideas and to explore new ways to communicate science
#IndustrialDesign is a PROCESS OF DESIGN applied to products where design precedes manufacture. Is the #creative act of determining & defining a product's form and features and as an applied art focuses on a combination of aesthetics, user, form, function & physical ergonomics
Read 11 tweets
Hola! my name is Ale (they/she) and I'm taking part in the #GlobalScienceShow
Today I'll be showing you some of my works about my exploration of the microbial world with drawings! 🦠
Check @GlobalSciShow to follow the whole show🤩

#scicomm #divulgarciencia #comunicacienciachile
I did my PhD in marine #microbiology and now I draw #scicomm comics/zines and cartoons (and a tiny bit of animations) in Spanish&English, to highlight the diversity of the microbial world 🦠and people in STEM✨,
including #queerinstem #bipocinstem
Here a bio-reel👇🏾
The big majority of planet is microscopic and they have a key role in the ecosystem, biogeochemical cycles and evolution of living organisms! 🦠
Our microbial world is huge and amazing!🤩
Read 13 tweets
Check out this special feature of #ProcB edited by @bkoskella @gut_health and me. Thanks to the authors for their excellent article contributions - and all articles are #freetoread. Hopefully there is something of interest for all #microbiome researchers here @RSocPublishing
Application of ecological and evolutionary theory to microbiome community dynamics across systems | Proceedings of the Royal Society B: Biological Sciences… @jamesemcdonald
Transmission efficiency drives host–microbe associations | Proceedings of the Royal Society B: Biological Sciences…
Matthew P. Edgington
and Tracey Chapman
Read 15 tweets
Vaccine received! I almost cried. As I was receiving the vaccine, I felt profound hope, joy and relief.
#shot #vaccine #covidvacccine #pfizer #mrna #spikeprotein #frontlineworkers #healthcareworkers #doctor #navajo #immunology #microbiology #virology #publichealth
I have been working on the front lines of COVID-19 on the Navajo Nation since March. Once, we were #1 in the WORLD per capita.
#vaccine #covidvacccine #pfizer #spikeprotein #frontlineworkers #healthcareworkers #doctor #navajo #immunology #microbiology #virology #publichealth
Today marks a new path towards having a world without COVID. Bless the tireless researchers and brave vaccine trail participates who made this possible.
#vaccine #covidvacccine #pfizer #frontlineworkers #healthcareworkers #doctor #navajo #immunology #microbiology #virology
Read 3 tweets
I have a few things to say this morning. A small but mighty 🧵.
First , I can't say thank you enough to @KatherineJWu for writing this amazing piece highlighting the crucial work of clinical laboratory scientists/medical technologists. Please read it:…
The article captures a piece of the talent, expertise, and dedication of these healthcare workers. This is especially true of my dear friend @darcyavelasquez, who works relentlessly day in and day out at @ChildrensColo to provide the best care possible to Colorado's children.
Sometimes it feels like the @KatherineJWu's, @kmess44's, and @jesscataldi's of the world are one-in-a-million. The failure to recognize the clinical laboratory (and people within it) for its importance in how healthcare works is not just a #COVIDー19 issue.
Read 22 tweets
I told my family from age 7 that I wanted to be a zoologist.

I am so proud of myself for all I have achieved so far and am grateful for life's opportunities everyday.

Our STEM journeys are important and I am excited to share mine with you.
I graduated in BSc (hons) Zoology from @AngliaRuskin in 2015.

I struggled, mostly with exams.

After three years, I convinced myself I would never be smart enough to pursue any post-graduate studies so I got a job at @sangerinstitute as an animal tech 🐭
I immediately fell back in love with science.

I realised that commitment and enthusiasm were just as valuable as being able to take an exam.

I learnt so much from so many and before I knew it, I was looking up papers in the evening just to better contribute to the conversations
Read 11 tweets
Here it is!

#Inktober2020 day 1 in my #PathogenPortraits series. After years of studying this in cow bums, it had to be #EcoliO157

It causes bloody diarrhoea & if that wasn't bad enough, sometimes kidney failure & death. More info @…
#sciart #microbiology Inktober2020 E. coli O157 c...
#Inktober2020 day 2 in my #PathogenPortraits series. 'The Clap' (Neisseria gonorrhoeae) b/c who doesn't 💚 green purulent discharge?

It's sexually transmitted but also from mother->newborn during birth to cause blindness.
More info:…

#sciart #microbiology Image
#Inktober2020 day 3 in my #PathogenPortraits series. The very 💛golden💛 #MRSA.

Minds it's own business on your skin, but if it gets inside, methicillin won't do a thing to stop it.

More info at #sciart #microbiology Methicillin resistant staph...
Read 34 tweets
Story time! (1/11) time to tell you all how I fell in love with #Microbiology #MyMicroStory #BlackInMicro
I grew up on a small farm in the rural South, and the first time that I became truly fascinated with microbes was when mad cow disease (a.k.a. bovine spongiform encephalopathy, or BSE) began to spread to humans (in the late 90s, I believe. (2/11)
We had about 30 head of cattle and my parents began to freak out and sold them all. They weren't sure how to describe the cause, but they knww it was some sort of infectious agent. I was both terrified and fascinated! (3/11)
Read 11 tweets
#Haemolysis data indicates that #disruption of host cell #membranes by rotating #flagella is physically possible, despite what previously published measurements with firing gold nanobeads at tissue cultures tells us.

[Pls read the paper for the more complex story with E.coli]
But what if #flagella did penetrate host cell #membranes? What might that mean?
Well, in vitro at least, #Ecoli and #Salmonella #flagella can enhance #actin #polymerization rates. Interactions with #Cofilin-1 (CFL) had an additive effect... Actin polymerisation rates with flagella from E. coli (H6, H
Read 8 tweets
8 years since the first manuscript draft but it's finally here!

The interaction of #Ecoli O157 :H7 and #Salmonella Typhimurium #flagella with host cell #membranes and cytoskeletal components | #Microbiology #Pathogenesis #Thread…
@strain9000 @ArielBlocker @MicrobioSoc This all started many 🌑🌒🌓🌔🌕🌖🌗🌘🌑 ago...

Jo Elvidge and I were looking at the role of #flagella in early infection of #Salmonella and #Ecoli in relevant animal tissue models (🐖🐄)

We spotted what looked like very intimate adherence... E.coli O157:H7 on Bovine terminal rectal cellsSalmonella Typhimurium on porcine epithelial cells
It was a toughie to quantify back then with the tools we had, but every time we looked, we saw it 🤓
Read 9 tweets
African S. Typhimurium ST313 has 23 Lineage 2-specific pseudogenes, discovered by @DrRobKingsley in 2009, inc ybjZ.

But what is function?

In collab with Jared Honeycutt @monack_lab, we've discovered that MacB (YbjZ) influences pathogenesis of ST313…
Genomes of 285 S. Typhimurium isolates revealed lineage-specific SNPs = macA & macB are pseudogenes

Suggesting that MacAB-TolC efflux pump is functional in S. Typhimurium ST19, but defective in ST313 Lineages 1 & 2
Beautiful expts designed by Jared Honeycutt & @monack_lab show MacA variant & truncated MacB protein made ST19 sensitive to C18G antimicrobial peptide

& the ST313 macAB SNPs reduced intra-macrophage replication & fitness in murine GI tract

See @monack_lab tweet for details
Read 6 tweets
Ok, sort of weird to say...but today I'm dedicating some time to SPIT (formally known as #Saliva). It's the super hot topic this week in the ever-changing #COVID19 diagnostic landscape we are living in, so let's take a quick peek at some of the evidence out there (thread)
I completely understand the importance of testing saliva, particularly as it relates to lack of supplies and resources. It can be a feasible option that basically eliminates HCW risk of infxn during collection. It can also save supplies: no swabs, media, possibly fewer reagents.
First paper is here: DOI: 10.1128/JCM.01659-20
-53 paired samples from OP and/or NP swabs, and saliva were collected
-Standard RNA extraction methods were used for the swab samples, a quick extraction method was used for saliva. Handling high-viscosity samples is discussed.
Read 20 tweets
Daily Bookmarks to GAVNet 07/30/2020…
Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic | Nature Microbiology…

#pandemic #evolutionary #origins #microbiology
Strike 1: Gold; Strike 2: Dollar; Strike 3: Inflation Expectations – Alhambra Investments…

#inflation #gold #expectations #investments
Read 6 tweets
I just want to be clear: while I understand and have similar frustrations with turnaround times for #COVIDー19 testing, I'm afraid the angst is falling on the laboratories...and I do not feel that is fair or appropriate. (Small thread)
The clinical laboratory is full of living, breathing, intelligent human beings. The work takes skill and time. Often, labs are understaffed and there has been a shortage of trained clinical lab scientists FOR A WHILE. There are only so many tests a person can crank out in a day.
Even if a lab has all the staff they need, there's only so much testing that can be done when a) your instruments are full b) you cannot get the supplies you need to run these tests. Seems like many people think labs have unlimited access to very expensive instruments...nope.
Read 8 tweets
Hey, friends. Here's what's up in the world of #COVID19 literature from the last 24 hours (7/23). Simple summaries provided, as always, follow the link for original manuscripts. BE WELL! #IDtwitter #MedED #MedTwitter #Microbiology #InfectiousDiseases
1. Title: Addendum to: Children are not COVID-19 super spreaders: time to go back to school
Brief Study Design: This is a letter (addendum) to the author’s original research paper (cited in the letter and can be accessed from it).
Simple Summary: Contact-tracing studies have demonstrated that children have a significantly lower attack rate of COVID-19 compared to adults.
Read 43 tweets
Looking for ways to bring discussions of #racism in your #science classes? Some ideas I use in class & in talks e.g. genome-wide sequencing studies, databases are skewed. Must be accounted for when extrapolating these data (e.g. personalized medicine)… 1/n
Especially when those findings are used to develop decision #algorithms otherwise #racism gets "baked in" #ArtificialIntelligence is not neutral. Healthcare outcomes reflect societal racism…
Which means that structural #racism can kill #cancer patients "Black patients with breast cancer and other malignancies face historical inequities that are ingrained but not inevitable"…
Read 16 tweets
Recently we got a research paper accepted by @jhieditor about how hand soap influences the growth of CPE in sinks. Here’s a few illustrations I drew explaining the background and some results. #microbiology #science #antibioticresistance ImageImageImageImage
Here is the paper, it might get lost in a world of COVID but we’re proud of it, also it’s open access.…
Read 5 tweets

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