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Nick Krontiris Profile picture
@nick_krontiris
Apr 24 • 8 tweets • 3 min read Twitter logo Read on Twitter
This systematic review and meta-analysis suggests that adherence to a healthy lifestyle is likely to reduce the risk of breast cancer.
- The main components included in the healthy lifestyle indices were: diet, physical activity, alcohol consumption and body mass index (BMI); followed by tobacco consumption, supplements use, and breastfeeding.
- Most of the prospective studies included five variables in the index : diet, physical activity, alcohol and tobacco consumption and BMI...
...while most of the retrospective studies included between five and six variables in the index: diet, physical activity, alcohol consumption, BMI, breastfeeding and/or supplement use.
- A total of 31 studies were included in the systematic review, while in the meta-analysis 29 articles evaluating the association between a healthy lifestyle index and breast cancer risk were assessed.
- High versus low adherence to a healthy lifestyle index was associated with a 20% decrease in breast cancer risk.
- Consistent reductions were also shown for postmenopausal and for molecular subtypes for those females most adherent to the WCRF/AICR and ACS lifestyle recommendations, while for premenopausal breast cancer the evidence was inconclusive.
Lifestyle quality indices and female breast cancer risk: A systematic review and meta-analysis (open access)

doi.org/10.1016/j.advn…

#nutrition #diet #Obesity #smoking #alcohol #exercise #Women #cancer

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More from @nick_krontiris

Nick Krontiris Profile picture
Apr 26
The findings of this one suggest that even though exercise may be beneficial for some aspects of children's cognition (information processing speed), those with higher levels of habitual physical activity may also benefit in other aspects too (executive control efficiency).
- A 15 min bout of physical exercise benefited children's overall information processing speed the most, whereas the efficiency of executive control and other attention networks (alerting and orienting) was unaffected by the duration of the bout.
- However, exercise duration affected the interactive functioning of executive control and orienting networks in more active children, suggesting that the dose–response relation of interest may be moderated by children's habitual physical activity level.
Read 9 tweets
Nick Krontiris Profile picture
Apr 26
This review tries to address the ideal duration and intensity of physical activity, and the types of exercise for optimizing lifelong cardiovascular health, longevity, and healthspan. Image
Summary:
- Physical fitness is the single best predictor of life expectancy and healthspan. Try to achieve and maintain a high level of physical fitness throughout life.
Read 10 tweets
Nick Krontiris Profile picture
Apr 26
In this one, obesity, but not overweight, was associated with a higher risk of death from middle to older age, irrespective of the adiposity index used, suggesting that obesity should be prevented across the lifespan, including in individuals up to 85 years of age. Image
- Lower risk of mortality in older participants with overweight compared with normal weight when adiposity was assessed by the fat mass index was observed.
- However, the magnitude of this association was small and probably not clinically meaningful.
Read 10 tweets
Nick Krontiris Profile picture
Apr 25
In this one, a high dose (2.5mg) of phenylcapsaicin was associated with a plausible ergogenic effect on strength performance, muscle damage and peripheral perceived exertion in comparison to a placebo and a lower dose of 0.625mg during resistance training. Image
- The aim of this study was to explore the effects of low dose (0.625 mg) and high dose (2.5mg) of phenylcapsaicin on full squat performance, active muscle and overall body ratings of perceived exertion, muscle damage, protein breakdown, metabolic response, and 24-h recovery.
These assessments were approached under a randomized, triple-blinded, placebo-controlled, crossover design.
Read 9 tweets
Nick Krontiris Profile picture
Apr 25
This one in hyperinsulinemia- and hyperglycemia- prone mice suggests that both endurance and strength training can be effective ways to mitigate the impacts of hyperglycemia and hyperinsulinemia. Image
- In this study, both short-term endurance and strength training protocols controlled the elevated fasting glucose and insulin, leading to improved whole-body insulin sensitivity and glucose tolerance.
- While endurance exercise appeared to play a vital role in transcriptome and mitochondrial activity, strength exercise mainly affected post-translational mechanisms and protein synthesis.
Read 10 tweets
Nick Krontiris Profile picture
Apr 25
In this one, females with high levels of physical activity showed a more pronounced flexion-relaxation phenomenon compared to those with moderate and low levels of physical activity, suggesting that high levels of physical activity may lower risk for low back pain. Image
- The flexion relaxation phenomenon is characterized by the reduction of paraspinal muscle activity at maximum trunk flexion.
- This phenomenon is often absent or disrupted in individuals reporting lower back pain.
Read 7 tweets

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