Daniel Gewolb, MD Profile picture
May 21 9 tweets 5 min read Twitter logo Read on Twitter
Learning case in this 40 y/o F with history of whole brain radiation as a child for brain tumor treatment
#NeuroRad #neurosurgery #Neurology @TheASNR #NeuroTwitter #meded #radres ImageImageImageImage
Brain radiation is a risk factor for the development of meningiomas …this patient subsequently developed multiple meningiomas including this large frontal meningioma Image
The mass was treated and immediate post op CT shows expected post op change with the resection cavity, some hemorrhage, and pneumocephalus Image
1 month later the patient presents with worsening headaches so an MRI was ordered to eval for post op infection

It can be tricky teasing out organizing hematoma from purulent material on MR. CT may not be as helpful as hematoma will reduce in density overtime
we see here there are areas of restricted and intermediate diffusivity within the resection cavity which can be from purulence or blood product Image
Given the patchy intrinsic T1 hyperintensity, we know at least some of this is related to subacute blood Image
Patchy hypointensity on SWI is also out of proportion to what one would expect from free radical formation along the periphery in abscess, so this is mostly from blood and perhaps foci of pneumocephalus Image
However, there is too much vasogenic edema and mass effect for a 1 month post op. Post op edema and blood should progressively decrease while an infected cavity would increase ImageImage
OR confirmed both blood and pus

Learning points:


💡 PROGRESSIVE or OUT of proportion vasogenic edema suggests infection (though do NOT forget about possibility of tumor recurrence!)

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More from @daniel_gewolb

May 19
Interesting case of complicated acute bacterial rhinosinusitis in this child with no PMH presenting w/ HA, fever & L sided weakness

#NeuroTwitter #ent #radres #neurosurgery @TheASNR @ASHNRSociety @PhilipRChapman1 #radres #futureradres ImageImageImageImage
CT shows opacification of the frontal and anterior ethmoid sinuses without evidence of cortical dehiscence

💡 In peds, infection can spread through vascular channels w/o destroying the bone ImageImage
MR shows abnormal signal filling the sinuses with associated restricted diffusion 2/2 purulent material

Post contrast we see areas of relative hypoenhancement in comparison to the normal mucosa on the contralateral side ImageImageImage
Read 9 tweets
Mar 27
What is the most likely diagnosis in this adolescent with seizure? 🧠

(Sorry I have no CT without)

#neurotwitter #peds #Neurosurgery #Neurology @The_ASPNR @TheASNR #MedTwitter
What is the most likely diagnosis?
Answer: Confirmed supratentorial ependymoma

Predicting tumors is incredibly challenging in the absence of specific features …some learning points on the case in 🧵
Read 8 tweets
Mar 27
Case of a radiation induced pseudoaneurysm in this patient with headache and AMS 🧠

Imaging in thread #Neurosurgery #Neurology #neurotwitter #radres #MedEd #MedTwitter @TheASNR ImageImageImageImage
▶️Initial head CT shows subarachnoid hemorrhage centered in the right cerebellopontine angle cistern

▶️CTA confirms an aneurysm of the right anterior inferior cerebellar artery (AICA) ImageImage
▶️MR displays and ice cream shaped enhancing mass extending through the right internal auditory canal into the cerebellopontine angle cistern, consistent with a vestibular schwannoma #icecream

▶️Careful search into the history confirms the schwannoma was treated with radiation ImageImage
Read 4 tweets
Mar 21
What is the most likely diagnosis in this 25 y/o M with headache? 🧠

Answer later tonight #radres #Neurology #Neurosurgery #MedEd #MedTwitter #NeuroTwitter @RSNA ImageImageImageImage
Most likely diagnosis?
Answer: confirmed germinoma, all these masses are on the differential for a pineal region mass …perhaps the most helpful clue is the age and gender rather than the imaging 🧠
Read 7 tweets
Mar 20
Glioblastoma is the most common variety of astrocytoma

The presence of necrosis is the characteristic feature of glioblastoma

Imaging details in thread #Neurosurgery #neurotwitter #radres #MedTwitter #Neurology @TheASNR
Some correlates for high grade astrocytoma include necrosis, marked mass effect, restricted diffusion (often patchy, eccentric or nodular in glioblastoma), elevated CBV, enhancement, and older age

The presence of ependymal spread is another poor prognostic sign (shown below)
Important learning point: when dealing with glioblastoma, the neoplasm extent is not defined by the area of enhancement but rather by the entire area of T2/FLAIR abnormality. Microscopic infiltrating tumor clearly extends beyond the areas of enhancement. 🧠
Read 5 tweets
Mar 16
Preoperative approach to sellar region masses, what the surgeon needs to know (at least what I think they need to know)

Additional reporting tips from surgeons are welcomed and encouraged! #Neurosurgery @TheASNR #radres #MedEd #MedTwitter #futureradres #endocrine #Neurology
1️⃣Where is the mass located?

Is it sellar based? suprasellar (S)? clival? Planum sphenoidale (PS)? Tuberculum sellae (arrow)?

▶️Location can change operative approach including but not limited to subfrontal vs transsphenoidal
2️⃣Where is the normal pituitary gland?

▶️this can be tough when the mass is large but the normal tissue often enhances more avidly than tumor so look for a strip of relatively avid enhancement along the periphery of the mass. Surgeons do not want to remove normal pit tissue
Read 10 tweets

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