Janiesaysyay Profile picture
May 26, 2023 β€’ 8 tweets β€’ 5 min read β€’ Read on X
πŸ’‰πŸ’‰ I'm A Believer πŸ’‰πŸ’‰

I thought love was only true in fairytales... Image
I believe this virus is scary. > Image
I believe the πŸ’‰s help prevent against serious illness & death. > ImageImage
I believe πŸ’‰πŸ’‰ adverse events are from the virus. > Image
I believed in this administration. > Image
I believe I have cancer. > Image

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More from @janiesaysyay

Sep 5
πŸ’Ž Another brilliant research paper from Pretorius et al.
#DiamondsOnTheSolesOfHerShoes

It's interesting to hypothesize what these findings might mean in light of the C0VID πŸ’‰'s mRNA/spike protein persistence in the body, and its accompanying dose of billions of lipid nanoparticles in systemic circulation. >Image
A theory > Image
> Image
Read 21 tweets
Aug 24
πŸ§¬πŸ’‰ So Into You ~ mRNA Integration πŸ’‰πŸ§¬

#DIM the lights, put on some slow music,

a new preprint from πŸ§‘β€πŸ”¬πŸ‘©β€πŸ”¬ at Jackson Lab is out looking at early transient innate immune responses in myeloid cells to the C0VID πŸ’‰

Their results inadvertently uncover another possible mechanism for integration of the C0VID πŸ’‰ RNA into the human genome.

🧡
tinyurl.com/y4nk5nhv
The scientists used single cell multi-omics programming, antibody and cytokine profiles to uncover:
"a distinct myeloid priming program induced by Type I interferons after the first mRNA dose, and a broader boosting response involving both Type I and Type II interferons after the second mRNA dose or Ad26.COV2.S." >Image
Image
They compared different expressions of genes in monocytes and dendritic cells and found that interferon stimulated genes (ISGs) were upregulated. > Image
Read 17 tweets
Jul 22
Creutzfeldt Jakob Disease

2 interesting papers on blood signatures for
Sporadic CJD.

Researchers found 38 different DNA methylation sites related to sCJD.

9 of these sites were replicated in a further study, with sites in or close to genes: FKBP5, AIM2, UHRF1, KCNAB2 successfully replicated, specific to sCJD.

These were specific to sCJD vs other prion disease, or AD and found only in the blood, not brains of sCJD patients, suggesting a possible blood biomarker.
>
tinyurl.com/bdnn7ysrImage
"Top 10 gene ontologies enriched in genes overlapping DMPs as identified using MetaCore (p value threshold = 0.1)." -Fig. 2
> Image
"Loss of DNA methylation at 2 sites on the AIM2 promoter correlates with disease severity.
AIM2 is a key component of the inflammasome pathway...drives IL-1Ξ²"
> Image
Read 10 tweets
Jun 24
Tendons are made of collagen.
SARS2 degrades collagen.
tinyurl.com/y37ryb6j x.com/SalvMattera/st…Image
Sorry, that should be dysregulates collagen in the muscles and bones. > https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2023.952278/full
> https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2023.952278/full
Read 8 tweets
Jun 5
⏳ Hanginaround 2 βŒ›οΈ

COVID-19 mRNA πŸ’‰ Component Persistence

🧡Image
⏳
> Image
βŒ›οΈ
> Image
Read 15 tweets
Jun 2
πŸ–‡οΈ Up Around the Bend πŸ–‡οΈ

Spike Amyloidogenesis Theory

🧡 Based on research by: Nystrom & Hammerstrom, Pretorius &  Kell, Kevin McCairn, Kevin McKernan, Walter Chesnut, Greg Harrison et al., me, and many others.
πŸ“Ž
> Image
πŸ“Ž
> Image
Read 21 tweets

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