Physician-Scientist, 👶🏽 Neurologist, Assistant Prof- UCISOM & CHOC. Early life exercise, neural epigenetics & 🧠 plasticity. Tweets my own. #BlackinNeuro
Jan 9, 2023 • 8 tweets • 3 min read
Finally published! 🎉 reposting d/t broken link in first thread:
Early-life exercise primes the murine neural epigenome to facilitate gene expression and hippocampal memory consolidation | Communications Biology nature.com/articles/s4200…
Our study discovers both new and well-known #geneexpression programs involved in #hippocampal memory following #adolescent#exercise, and also investigates two #epigenetic modifications in these mechanisms (open access @CommsBio)
Jan 9, 2023 • 9 tweets • 4 min read
It’s here! 🎉 Our study reveals both new and known #geneexpression programs involved in hippocampal memory following #adolescent#exercise, and also investigates two #epigenetic regulatory mechanisms (open access @CommsBio) 1/
urldefense.com/v3/__https://r…$
We asked which genes are regulated after aerobic exercise (voluntary wheel running) in adolescent #hippocampus using a transgenic mouse & technique we developed for simultaneous sequencing of the #epigenome and translatome in excitatory #neurons. 2/
