While the other four boroughs take a welcome slight rightward turn, the #Bronx continues its trajectory of increased deaths in #NYC from #Covid19.

Now one person in 1,262 in the Bronx has lost their life to the pandemic

Data from www1.nyc.gov/site/doh/covid… Deaths are a lagging indicator, colleagues at @MontefioreNYC are seeing fewer new cases presenting, so hopefully the curve will decelerate in the #Bronx.

Now one in 1,154 in the borough has died from #COVID19.

Andy Feinberg has written a review about #epigenetics in @NEJM.

Unfortunately, it’s damaging to the field of human epigenetics research.

The Key Role of Epigenetics in Human Disease Prevention and Mitigation
nejm.org/doi/full/10.10… A couple of historical inaccuracies to start. Waddington was saying the opposite – cell fate (the cellular event in epigenesis) is probabilistic, not deterministic. The major point he was making was that genes have a role in influencing epigenesis, a major argument at the time

I wasn’t really expecting this tweet to get such a response. It clearly hit a communal nerve. Probably in part because I was deliberately provocative 1/

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2/ Did @ryanlisterlab really show that DNA methylation has no role in transcriptional repression? Of course not. But they do show that it does not seem to be enough by itself to change the expression of genes