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Simmaron Research Profile picture
Simmaron Research
@RedefiningMECFS
Official Twitter account for Simmaron Research, a non-profit scientifically redefining ME/CFS. Visit our site to learn more.
Sep 15 • 5 tweets • 2 min read
We published new science for an #ME subset! Our 2nd BH4 publication explains why BH4 is elevated in #ME patients with #OrthostaticIntolerance. Using original experiments, we identify 4 important findings: 1/5 #POTS #MECFS Image 1. Less utilization of oxygen in blood stimulates Non-oxidative Pentose Phosphate Pathway, which could produce high BH4. We studied the effect of hypoxia on the PPP pathway, BH4 and BH2. #ME 2/5 Image
Feb 8, 2023 • 5 tweets • 5 min read
A new publication by Simmaron!

“Potential molecular mechanisms of chronic fatigue in #LongCOVID and other viral diseases”
A hypothesis-driven review article demonstrates a diverse range of inflammatory & metabolic pathways responsible for fatigue of viral origin. 1/5 Image These 5 viruses (#HHV6, #Powassan, #EBV, #HIV, #SARS-CoV2) trigger unique immunological reactions, yet lead to similar inflammation + muscle fatigue. Examining these pathways can bring light to possible treatments for #mecfs #longcovid.

rdcu.be/c48cR 2/5