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Christian Mosimann Profile picture
Christian Mosimann
@chrmosimann
Johnson Chair & Assoc. Prof @CUAnschutz, @CUDevBio, @molbcu, @CSD_CUAMC. #devbio, #evodevo, cell fate, #zebrafish, transgenes, #CHD, @ZDMSociety @InfoIzfs.
Jan 13, 2022 • 16 tweets • 5 min read
Remarks on faculty job searches (as 'tis the season):
Chances are, as a faculty candidate you apply to several job ads.

Dozens. More.

You wait. You hope.

(quick thread)
1/n
 #PILife #PDLife #AcademicJobs Some places will respond with a rejection pretty quickly. Form letter.

Sometimes hilariously addressed to Dear [Applicant Name3].

Are you just a number? At this stage, likely.

Others never get back to you. Or years (!) later.

2/n
Sep 22, 2020 • 18 tweets • 6 min read
As undergrad, I struggled immensely with this: reading and omg understanding papers.

Especially as non-native English speaker.

I did develop a system that helped me back then.

Bear with me it is pretty...mundane. 1/n

#reading #PhDLife #PDlife #undergradlife #papers #science I printed each paper. And while reading I used a yellow, a green, and a pink highlighter.

When reading, I labeled every first mention of an abbreviation in green.

This helped me to find their meaning quickly again when deep into the text.

2/n
Aug 19, 2020 • 4 tweets • 2 min read
This is every molecular biologist's nightmare - vector and PCR product contamination across samples.

We can sequence so deep now that all kinds of details come to light! I bet lots of us "reproduced" aspects of this in our own labs - i.e. a genotyping you do often starts to show up in every PCR you do, etc.

DNA always finds a way.

#mobio #devbio #benchwork
Jul 7, 2020 • 4 tweets • 6 min read
Honored & grateful to receive the @ZDMSociety award in these trying times.

The award also recognizes our amazing international trainees using #zebrafish #devbio as cardiovascular disease model, first @UZH_en & now @CUAnschutz - and our fantastic collaborators!

Thx all🍾🐟! Special shout-out to @FelkerAnastasia @karin_prummel @aburger2009, our collaborators @ClaudioCantu81 @d_zimmerli @KevinMMA13 @DanielaPanakova @PanakovaLab @George_Hausmann and all who were part of our BCL9 work cited in the award:
genesdev.cshlp.org/content/32/21-… Image
Jun 19, 2020 • 8 tweets • 6 min read
Happy our review on the lateral plate mesoderm is out @Dev_journal, with @karin_prummel & @Susan81643382 (open access).

Our first attempt at reviewing the fascinating, wacky, complex biology as Development at a Glance with poster!
#devbio #evodevo
dev.biologists.org/content/147/12… Image The LPM forms several central cell fates and organ systems, including the heart, endothelium, blood, limb connective tissue, and much more.

This seemingly weird combo of downstream fates seems unrelated the adult body - but they all share a common LPM origin!
Jun 19, 2020 • 6 tweets • 2 min read
Fun fact:
most PIs themselves never had (or sought) any actual formal training for any of this. Similar for teaching or mentoring.

Frequent attitude:
"winging it" is normal/badge of honor/funny.

Don't want to say it shows. But it totally does. Few quick additions:

"Budgeting" or lab budgets are often not that complex. Salaries are pre-defined. Reagents over time sum up to an average consumption and can be estimated. And often you get help.

I always dreaded the book keeping but it's useful and gives peace of mind.
Apr 22, 2020 • 7 tweets • 3 min read
Just co-chaired the first #ZFish20 concurrent session at #TAGC20 @GeneticsGSA.

Short thread after the fact:

1) WE CAN DO THIS!

1/7 2) Great technical support with setting up, etc. from the assigned technicians.

No need to sweat, and it was great to see enthusiastic smiles and humor in the 10min before the session start!

2/7
Apr 22, 2020 • 12 tweets • 7 min read
Kicking off concurrent sessions #TAGC20, "Genetic Control of Development and Regeneration (#Zebrafish)!
@zoom_us tested for all speakers, @snillum1 & I will guide Q&A, 400+ attendees logged in, and go! First talk by Daniel Zuppo (Tsang lab, UPittsburg) on foxm1 in proliferating cardiomyocytes upon heart injury.

Trx factors & beautiful stainings, what's not to ❤️!
#ZFish20
Apr 20, 2020 • 7 tweets • 4 min read
#Zebrafish folks and beyond, join us - free from your living room, home office, bed, etc.! Wed April 22 at 1:30pm-3:30pm (EDT), @snillum1 & I are looking forward to chair "Genetic Control of Development and Regeneration" (#Zebrafish):
app.genetics-gsa.org/tagc/abstracts…